W4122: Beneficial and Adverse Effects of Natural Chemicals on Human Health and Food Safety

(Multistate Research Project)

Status: Active

SAES-422 Reports

01/05/2018

  1. Aleksic B, Bailly S, Draghi M, Pestka JJ, Oswald IP, Robine E, Bailly JD, Lacroix MZ. Production of four macrocyclic trichothecenes by stachybotrys chartarum during its development on different building materials as measured by uplc-ms/ms. Building and Environment 2016, 106, 265-273.
  2. Bates MA, Brandenberger C, Langohr II, Kumagai K, Lock AL, Harkema JR, Holian A, Pestka JJ. Silica triggered autoimmunity in lupus-prone mice blocked by docosahexaenoic acid consumption. Plos One 2016, 11: e0160622.
  3. Bates MA, Gilley KN, Jackson-Humbles DN, Harkema JR, Holian A, Pestka JJ. Silica-triggered multi-organ autoimmune gene expression in lupus-prone mice is ablated by docosahexaenoic acid consumption. FASEB Journal 2017, 31.
  4. Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang J, Löhr CV, Williams DE, Dashwood RH, Hendrix DA, Ho E. Long Non-Coding RNAs and Sulforaphane: A Target for Chemoprevention and Suppression of Prostate Cancer. Journal of Nutrition Biochemistry 2017, 42:72-83.
  5. Bibi S, de Sousa Moraes LF, Lebow N, Zhu MJ. Dietary green pea protects against DSS-induced colitis in mice challenged with high-fat diet. Nutrients 2017, 9: 509
  6. Bibi S, Kowalski RJ, Zhang S, Ganjyal GM, Zhu MJ. Stability and functionality of grape pomace Used a nutritive additive during extrusion process. Journal of Food Processing & Technology 2017, 8:680.
  7. Bibi S, Kang Y, Du M, Zhu MJ. Maternal high-fat diet consumption enhances offspring susceptibility to DSS-induced colitis in mice. Obesity 2017, 25: 901-908
  8. Borresen E, Brown DG, Harbison G, Taylor L, Fairbanks A, O’Malia J, Bazan M, Rao S, Baily S, Wdowik M, Weir TL, Brown RJ, Ryan EP. A randomized-controlled trial to increase navy bean or rice bran consumption in colorectal cancer survivors. Nutrition & Cancer 2016, 68:1269-1280
  9. Brown DG, Rao S, Weir TL, O’Malia J, Bazan M, Brown RJ, Ryan EP. Metabolomics investigation of tumors, adjacent colonic mucosa and stool from colorectal cancer patients. Cancer & Metabolism 2016, 4:11.
  10. Chen YS, Wang R, Dashwood WM, Löhr C, Williams DE, Ho E, Mertens-Talcott S, Dashwood R. A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat. Archives of Toxicology 2017, 91:3415-3425.
  11. Doerge DR, Woodling KA, Churchwell MI, Fleck SC, and Helferich WG. Pharmacokinetics of isoflavones from soy infant formula in neonatal and adult rhesus monkeys. Food Chemical Toxicology 2016: S0278-6915.
  12. Foster MT, Gentile CL, Cox-York K, Wei Y, Wang D, Estrada A, Reese L, Miller T, Pagliassotti MJ, Weir TL. Fuzhuan tea consumption imparts hepatoprotective effects and alters intestinal microbiota in high saturated fat diet-fed rats. Molecular Nutrition and Food Research 2016, 60:1213-12
  13. Gotthardt JD, Bello NT. Meal pattern alterations associated with intermittent fasting for weight loss are normalized after high-fat diet re-feeding. Physiology & Behavior 2017,174: 49-56.
  14. Housley L, Hsu A, Beaver LM, Wong CP, Stevens JF, Choi J, Jiang Y, Bella D. Williams DE, Shannon J, Dashwood RH, Ho E. Untargeted metabolic screen reveals changes in human plasma metabolite profiles following consumption of fresh broccoli sprouts. Molecular Nutrition and Food Research. In press.
  15. Johnson NB, Deck KM, Nizzi CP, Eisenstein RS. A synergistic role of IRP1 and FBXL5 in coordinating iron metabolism during cell proliferation. Journal of Biology Chemistry 2017, 292: 15976-15989
  16. Kang Y, Xue Y, Du M, Zhu MJ. Preventative effects of Goji berry in dextran sulfate sodium-induced colitis. Journal of Nutritional Biochemistry 2017, 40: 70-76.
  17. Kunde DA, Chong WC, Nerurkar PV, Ahuja KD, Just J, Smith, JA, Guven, N and Eri, RD Bitter melon extract protects against ER stress in LS174T colonic epithelial cells. BMC Complement Alternative Medicine. 2017, 17: 2.
  18. Lee DM, Battson ML, Jarrell, Cox-York K, Foster MT, Weir TL, Gentile CL. Fuzhuan tea reverses arterial stiffening following modest weight gain in mice. Nutrition 2017, 33:266-270.
  19. Lemas DJ, Young BE, Baker PR, Tomczik A, Soderborg TK, Hernandez TL, de la Houssaye BA, Robertson CE, Rudolph MC, Ir D, Patinkin ZW, Krebs NF, Santorico SA, Weir TL, Barbour LA, Frank DN, Friedman JE. Alterations in human milk leptin and insulin impact early changes in the infant gut microbiome. American Journal Clinical Nutrition 2016, 103:1291.
  20. Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L, Waters KM and Williams DE. Dibenzo[def,p]chrysene Transplacental Exposure in Wild-Type, Cyp1b1 Knockout, and CYP1B1 Humanized Mice. Molec. Carcinogenesis 2017, 56:163-171.
  21. Monson MS, Cardona CJ, Coulombe RA, Reed KM. Hepatic transcriptome responses of domesticated wild turkey embryos to aflatoxin B1. Toxins 2016, 8: 16.
  22. Monson M S, Coulombe RA, Reed KM. Sensitivity and response of poultry to aflatoxin B1 exposure. Agriculture 5 (3) 742-777. 2016, doi:10.3390/agriculture50x000x.
  23. Oni EN, Halikere A, Li G, Toro-Ramos AJ, Swerdel MR, Verpeut JL, Moore JC, Bello NT, Bierut LJ, Goate A, Tischfield JA, Pang ZP, Hart RP. Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele. Scientific reports 2016, 6: 34341.
  24. Palmoera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E. The Phytochemical 3, 3’-Diindolylmethane Decreases Expression of AR-Controlled DNA Damage Repair Genes Through Repressive Chromatin Modifications and is Associated with DNA Damage in Prostate Cancer Cells. Journal of Nutritional Biochemistry 2017, 47:113-119.
  25. Pestka JJ, Clark ES, Schwartz-Zimmermann HE, Berthiller F. Sex is a determinant for deoxynivalenol metabolism and elimination in the mouse. Toxins 2017, 9.
  26. Reed KM, Mendoza KM Abrahante J, Coulombe RA. Response of the Hepatic Transcriptomes of Domesticated and Wild Turkey to Aflatoxin B1. Presented at International Society of Animal Genetics, Dublin, IR. July 2017.
  27. Rendeiro C, Sheriff A, Bhattacharya TK, Gogola JV, Baxter JH, Chen H, Helferich WG, Roy EJ, Rhodes JS. Long-lasting impairments in adult neurogenesis, spatial learning and memory from a standard chemotherapy regimen used to treat breast cancer. Behavioral Brain Research 2016, 315:10-22.
  28. Riggs PK, Tedeschi LO, Turner ND, Braga-Neto U, Jayaraman A. The role of “omics” technologies for livestock sustainability. Archive Latinioam Production Animal 2017 25:147-153.
  29. Ritchie LE, Taddeo SS, Weeks BR, Carroll RJ, Dykes L, Rooney LW, Turner ND. Impact of novel sorghum bran diets on DSS-induced colitis. Nutrients 2017, 9: E330.
  30. Schwartz-Zimmermann HE, Hametner C, Nagl V, Fiby I, Macheiner L, Winkler J, Danicke S, Clark E, Pestka JJ, Berthiller F. Glucuronidation of deoxynivalenol (don) by different animal species: Identification of iso-don glucuronides and iso-deepoxy-don glucuronides as novel don metabolites in pigs, rats, mice, and cows. Archives of Toxicology 2017. In press.
  31. Seidel DV, Azcarate-Peril MA, Chapkin RS, Turner ND. Shaping functional microbiota using dietary bioactives to reduce colon cancer risk. Seminars in Cancer Biology 2017, 46:191-204.
  32. Sheflin AM, Borresen EC, Kirkwood J, Boot C, Whitney AK, Lu S, Brown RJ, Broeckling CD, Ryan EP, Weir TL. Dietary Supplementation with Rice Bran or Navy Bean Alters Gut Bacterial Metabolism in Colorectal Cancer Survivors. Molecular Nutrition and Food Research 2017, 61:1500905.
  33. Sheflin AM, Melby C, Carbonero F, Weir TL. Linking dietary patterns with gut microbial composition and function, Gut Microbes, 2017. 8:113-129
  34. Sun X and Zhu MJ. AMP-activated protein kinase: a therapeutic target in intestinal diseases. Open Biology 2017, 7: 170104.
  35. Sun X, Yang QY, Rogers CJ, Du M, Zhu MJ. AMPK regulate intestinal differentiation via histone modification of CDX2. Cell Death and Differentiation 2017, 24: 819-831.
  36. Tinder AC, Puckett RT, Turner ND, Cammack JA, Tomberlin JK. Bioconversion of sorghum and cowpea by black soldier fly (Hermetia illucens (L.)) larvae for alternative protein production. Journal of Insects as Food and Feed 2017, 3:121-130.
  37. Turner ND and Lloyd SK. Association between red meat consumption and colon cancer: A systematic review of experimental results. Experimental Biology & Medicine 2017, 242:813-839.
  38. Wang B, Fu X, Zhu MJ, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A mediated Zfp423 DNA demethylation. Journal of Molecular Cell Biology 2017, 9:338-349.
  39. Wang B, Fu X, Liang X, Deavila JM, Wang Z, Zhao L, Tian Q, Zhao J, Gomez NA, Trombetta SC, Zhu MJ, Du M. Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRa+ adipose progenitors. Cell Discovery 2017, 3:17036.
  40. Wang S, Liang X, Yang Q, Fu X, Zhu MJ, Rodgers BD, Jiang Q, Dodson MV, Du M. Resveratrol enhances brown adipocyte formation and function by activating AMP-activated protein kinase (AMPK) a1 in mice fed high-fat diet. Molecular Nutrition and Food Research 2017, 61: 1600746.
  41. Whitney AK and Weir TL. Inhibitory activity of Fuzhuan tea fractions against Salmonella enterica and enteric pathogens. Current Topics in Phytochemistry 2016, 13:17-27.
  42. Wu W, Zhou H-R, Bursian SJ, Link JE, Pestka JJ. Calcium-sensing receptor and transient receptor ankyrin-1 mediate emesis induction by deoxynivalenol (vomitoxin). Toxicological Sciences 2017, 155:32-42.
  43. Wu W, Zhou H-R, Pestka JJ. Potential roles for calcium-sensing receptor (casr) and transient receptor potential ankyrin-1 (trpa1) in murine anorectic response to deoxynivalenol (vomitoxin). Archives of Toxicology 2017, 91:495-507.
  44. Xue Y, Du M, Zhu MJ. Quercetin suppresses NLRP3 inflammasome activation in epithelial cells triggered by Escherichia coli O157:H7. Free Radical Biology and Medicine 2017, 108:760-769
  45. Xue Y, Zhang D, Du M, Zhu MJ. Dandelion extract suppresses reactive oxidative species and inflammasome in intestinal epithelial cells. Journal of Functional Food 2017 29: 10-18.
  46. Xue Y, Du M, Sheng H, Hovde CJ, Zhu MJ. Escherichia coli O157:H7 suppress host autophagy and promote bacterial adhesion via Tir-mediated and cAMP-independent activation of protein kinase A. Cell Death and Discovery 2017, 3, 17055.
  47. Xue Y, Zhang H, Sun X, Zhu MJ. Metformin improves ileal epithelial barrier function in interleukin-10 deficient mice. PloS ONE 2016, 11: e0168670
  48. Yang G, Bibi S, Du M, Suzuki T, Zhu MJ. Regulation of the intestinal tight junction by natural polyphenols: a mechanistic perspective. Critical Reviews in Food Science and Nutrition 2017, 595: 3830-3839.
  49. Yin Q, Tang L, Cai K, Tong R, Sternberg R, Yang X, Dobrucki LW, Borst LB, Kamstock D, Song Z, Helferich WG, Cheng J, Fan TM. Pamidronate Functionalized Nanoconjugates for Targeted Therapy of Focal Skeletal Malignant Osteolysis. Proc Natl Acad Sci U S A. 2016, 113:E4601-9.
  50. Zhang X, Cook KL, Warri A, Cruz IM, Rosim M, Riskin J, Helferich W, Doerge D, Clarke R, Hilakivi-Clarke L. Lifetime genistein intake increases the response of mammary tumors to tamoxifen in rats. Clinical Cancer Research 2017. 23: 814-824.
  51. Zhao J, Yang Q, Zhang L, Liang X, Sun X, Wang B, Chen Y, Zhu MJ, Du M. AMPKa1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development. Biochemical and Biophysical Research Communications 2017 491: 508-514.
  52. Zou T, Yang Q, Wang B, Zhu MJ, Nathanielsz PW, Du m. Resveratrol supplementation to high fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring. Journal of Physiology 2017, 595:1547-1562.

12/04/2018

Publications:

45 new publication by W4122 members (bolded) in 2017-2018 addressing effects of bioactive nutrients on health and chronic disease risk, as well as basic insights into metabolism, development of new methodology and technologies.

Molero, L., Campos, L., Sosa, L., Mao, Y., Flores, N., Delgado, E., Lozano, K. 2018. Development and Characterization of Glandless Cottonseed Meal/Pullulan Fine Fiber Mats. Archives of Nanomedicine, Accepted for publication July 2018.

Cuj-Laines, R., Hernández-Santos, B., Reyes-Jaquez, D., Delgado, E., Juarez-Barrientos, J.M., Rodriguez-Miranda, J. 2018. Physicochemical properties of ready-to-eat extruded nixtamalized maize based snacks enriched with grasshopper. International Journal of Food Science & Technology. Accepted for publication. DOI:10.1111/ijfs.13774.

Kim, E., G.A. Wright, R.S. Zoh, B.S. Patil, G.K. Jayaprakasha, E.S. Callaway, I. Ivanov, N.D. Turner, R.S. Chapkin. 2018. Establishment of a multi-component dietary bioactive human equivalent dose to delete damaged Lgr5+ stem cells using a mouse colon tumor initiation model. European Journal of Cancer Prevention (In press).

Seidel, D.V., S.S. Taddeo, M.A. Azcarate-Peril, R.J. Carroll, and N.D. Turner. Dried plums protect against chemically-induced colon carcinogenesis in Sprague Dawley rats. Journal of Nutrition (Accepted with revision).

Nerurkar, P.V.*, Orias, D., Soares, N., Kumar, M. and Nerurkar, V.R. Momordica charantia (Bitter melon) modulates adipose inflammasome gene expression and adipose-gut inflammatory crosstalk in high-fat diet (HFD)-fed mice. J Nutritional Biochem, Submitted revisions Oct 2018

Housley, L, Magaana, A.A., Hsu, A., Beaver, L.M., Wong, C.P., Stevens, J.F., Choi, J., Jiang, Y., Bella, D., Williams, D.E., Maier, C.S., Shannon, J., Dashwood, R.H. and Ho, E. (2018). Untargeted Metabolic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts. Molec. Nutr. Fd. Res., Jan 28, 2018 [Epub ahead of print], PMID: 29377494.

Hummel, J.M., Madeen, E.P., Siddens, L.K., Uesugi, S.L., McQuistan, T., Anderson, K.A., Turteltaub, K.W., Ognibene, T.J., Bench, G., Krueger, S.K., Harris, S., Smith, J., Tilton, S.C., Baird, W.M. and Williams, D.E. (2018) Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in Humans: Impact of Co-Administration of Smoked Salmon and BaP Dietary Restriction. Fd. Chem. Toxicol. 115:136-147, PMID: 29518434.

Williams, D.E. (2018) Association is not Causation (letter). Toxicol. Sci. 164:3.,DOI: 10.1093/toxsci/kfy095.

Bibi, S., M. Du, and M. J. Zhu. 2018. Dietary red raspberries reduces colorectal inflammation and carcinogenic risk in DSS-induced colitis in mice. Journal of Nutrition, 148, 667-674.

Bibi, S., Y. Kang, M. Du, and M. J. Zhu. 2018. Dietary red raspberries attenuate dextran sulfate sodium-induced acute colitis. Journal of Nutritional Biochemistry, 51:40-46.

Sun, X., and M. J. Zhu. 2018. Butyrate inhibits indices of colorectal carcinogenesis via enhancing α-ketoglutarate-dependent DNA demethylation of mismatch repair genes. Molecular Nutrition Food Research, 62: 1700932.

Sun, X., M. Du, D. A. Navarre and M. J. Zhu. 2017. Purple potato extract promotes intestinal epithelial differentiation and barrier function by activating AMP-activated protein kinase. Molecular Nutrition and Food Research, 62(4):1700536.

Sun, X., Q. Y. Yang, C. J. Rogers, M. Du, and M. J. Zhu. 2017. AMPK regulate intestinal differentiation via histone modification of CDX2. Cell Death and Differentiation, 24: 819-831.

Sun, X., X. Fu, M. Du, and M. J. Zhu. 2018. Ex vivo gut culture for tracing gut epithelial development. Open Biology, 8: 170256.

Wang, B., F. Zhang, H. Zhang, Z. Wang, Y. Ma, M. J. Zhu, and M. Du. 2017. Alcohol intake aggravates adipose browning and muscle atrophy in cancer associated cachexia. Oncotarget, 8: 100411-100420.

Wang, B., Z. Wang, J. M. de Avila, M. J. Zhu, F. Zhang, N. A. Gomez, L. Zhao, Q. Tian, J. Zhao, J. Maricelli, H. Zhang, B. D. Rodgers, and M. Du. 2017. Moderate alcohol intake induces thermogenic brown/beige adipocyte formation via elevating retinoic acid signaling. FASEB Journal, 31:4612-4622.

Xing, T., Y. Kang, X. Xu, B. Wang, M. Du, and M. J. Zhu. 2018. Raspberry supplementation improves insulin signaling and promotes brown-like adipocyte development in white adipose tissue of obese mice. Molecular Nutrition and Food Research, 2018, 62:1701035.

Zhao, J., Q. Yang, L. Zhang, X. Liang, X. Sun, B. Wang, Y. Chen, M. J. Zhu, and M. Du. 2017. AMPKa1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development. Biochemical and Biophysical Research Communications, 491: 508-514.

Zhao, L., T. Zou, N. A. Gomez, B. Wang, M. J. Zhu, and M. Du. (2018). Raspberry alleviates obesity-induced inflammation and insulin resistance in skeletal muscle through activation of AMP-activated protein kinase (AMPK) α1. Nutrition & Diabetes, 8: 39.

Zhu, M. J., Kang, Y., Y. Xue, X. Liang, M. P. Gonzalez Carcia, D. Rodgers, D. K. Kagel, M. Du. 2018. Red raspberries suppress NLRP3 inflammasome and attenuate metabolic abnormalities in diet-induced obese mice. Journal of Nutritional Biochemistry, 53:96-103

Zou, T., B. Wang, Q. Yang, J. M. de Avila, M. J. Zhu, J. You, D. Chen, and M. Du. 2018. Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) 1. Journal of Nutritional Biochemistry, 55:157-164.

Gentile CL and Weir TL. The gut microbiota at the intersection of diet and health. Science (in press)

Shah MS, DeSantis TZ, Yamal JM, Weir TL, Ryan EP, Cope JL, Hollister EB. Re-purposing 16S rRNA gene sequence data for within-case paired tumor, tumor-adjacent biopsy, and fecal samples to identify reproducible microbial markers for colorectal cancer. PLoS One (in press)

Soderborg TK, Mulligan CE, Clark SE. Babcock L, Janssen RC, Lemas DL, Johnson LK, Frank DN, Weir TL, Barbour LA, Hernandez TL, Kuhn KA, D’Alessandro A, El Kasim KC, Friedman JE (2018) The Gut Microbiota in Infants of Obese Mothers Increases Hepatic Inflammation and Susceptibility to Obesity and NAFLD in Germ-free Mice. Nature Communications (in press).

Stull VJ, Finer E, Bergmans RS, Febvre HP, Longhurst C, Manter DK, Patz J, Weir TL. (2018) Impact of Edible Cricket Consumption and Gut Microbiota in Healthy Adults, a Double-blind Crossover Trial. Scientific Reports. 8, 10762

Lee DM, Battson ML, Jarrell DK, Hou S, Ecton KE, Weir TL, Gentile CG. (2018) SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the intestinal microbiota in type II diabetic mice. Cardiovascular Diabetology, 17:62.

Gindin M, Febvre HP, Rao S, Wallace TC, Weir TL. (2018) Bacteriophage for Gastrointestinal Health (PHAGE) Study: Evaluating the Safety and Tolerability of Supplemental Bacteriophage Consumption. Journal of the American College of Nutrition. Doi: 10.1080/07315724.2018.1483783.

Battson ML, Lee DM, Weir TL, Gentile CG (2018) The gut microbiota as a novel regulator of cardiovascular function and disease. Journal of Nutritional Biochemistry 56: 1-15.

Salem G, Al-Feki W, Manter DK, Byrne P, Stromberger ME, Weir TL. (2018) Water stress tolerance of winter wheat (Triticum aestivum L.) genotypes are improved by ACC deaminase bacteria. Rhizosphere 8: 1-7.

Cox-York KC, Stoecker E, Hamm AK, Weir TL (2018) Microbial Metabolites in Cancer Promotion or Prevention. In: Microbiome and Cancer (ed. Robertson ES). Springer International Publishing, Cham, Switzerland.

Battson ML, Lee DM, Jarrell D, Hou S, Ecton K, Weir TL, Gentile CG (2017) Suppression of Gut Dysbiosis Reverses Western Diet-Induced Vascular Dysfunction. Am J Physiol- Endocrinol & Metabol doi: 10.1152/ajpendo.00187.2017.

Guha, S., Majumder, K. (2018). Structural-features of food-derived bioactive peptides with anti-inflammatory activity: A brief review. Journal of Food Biochemistry, DOI: 10.1111/jfbc.12531.

Li, Q., Kang, X., Shi, C., Li, Y., Majumder, K., Ninga, Z., Ren, Y. (2018). Moderation of hyperuricemia in rats via consuming walnut protein hydrolysate diet and identification of new antihyperuricemic peptides. Food & Function, 1: 107-116.

Chee, M., Majumder, K., Mine, Y. (2017). Intervention of dietary dipeptide gamma-L-glutamyl-L-valine (γ-EV) ameliorates inflammatory response in a mouse model of LPS-induced sepsis. Journal of Agricultural and Food Chemistry, 65: 5953–5960.

Majumder, K., Fukuda, T., Zhang, H., Sakurai, T., Taniguchi, Y., Watanabe, H., Mitsuzumi, H., Matsui, T., Mine, Y. (2017). Intervention of isomaltodextrin mitigates intestinal inflammation in a dextran sodium sulfate-induced mouse model of colitis via inhibition of toll-like receptor-4. Journal of Agricultural and Food Chemistry, 65: 810-817.

Fukuda, T., Majumder, K., Zhang, H., Matsui, T., Mine, Y. (2017). Adenine has an anti-inflammatory effect through the activation of adenine receptor signaling in mouse macrophage. Journal of Functional Foods, 28: 235-239.

Obeidat Y, Catandi GD, Carnevale EC, Chicco AJ, DeMann A, Field S, Chen T. A Multi-Sensor System for Measuring Bovine Embryo Metabolism Biosensors and Bioelectronics in press

Pennington ER, Sullivana EM, Fix A, Dadooc S, Zeczycki T, DeSantis A, Schlattner U, Chicco AJ, Brown DA, Shaik SR. Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. J Biol Chem in press, 2018.

Chicco AJ, Le CH, Gnaiger E, Dreyer HC, D’Alessandro A, Nemkov TG, Hocker AD, Prenni JE, Sindt N, Lovering AT, Subudhi AW, Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lesson from AltitudeOmics. J Biol Chem 293(18): 6659-6671, 2018. PMID: 29540485

Sloan DB, Warren JM, Williams AM, Wu Z, Abdel-Ghany SE, Chicco AJ, Havird JC. Cytonuclear integration and co-evolution. Nat Rev Genet., In press. PMID: 30018367

Chung DJ, Sparanga, GC, Chicco AJ, Schulte PM. Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol, 221:jeb174458, 2018. PMID:29643174

Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM. Mitochondria, temperature, and the pace of life. Integr Comp Biol. 2018 Apr 30. doi: 10.1093/icb/icy013. In press. PMID: 29718252

Obeidat Y, Evans AJ, Tedjo W, Chicco AJ, Carnevale EM , and Chen T Monitoring of Oocyte/Embryo Respiration Using Electrochemical-Based Oxygen Sensors. Sensors and Actuators B: Chemical, 276 (10):72-81, 2018.

Reed, K.M., Mendoza, K.M. Abrahante, J., and Coulombe, R.A. (2017). Response of the Hepatic Transcriptomes of Domesticated and Wild Turkey to Aflatoxin B1. Presented at the Annual Conference of the International Society of Animal Genetics, Dublin, IR. July 2017.

Reed, K.M., Mendoza, K.M., Abrahnte, Juan and Coulombe, R.A. (2018) Comparative Response of the Hepatic transcriptomes of Domesticated and Wild Turkey to Aflatoxin B1. Toxins 10 (1) 1-24. doi:10.3390/toxins10010042

 

 

12/08/2019

Bates, M.A, Akbari, P., Gilley, K.N, Jackson-Humbles, D.N, Wagner, J.G, Li, N., Kopec, A.K, Wierenga, K.M, Brandenberger, C., Holian, A., Benninghoff, A., Harkema, J.R, Pestka, J.J, (2018). Dietary Docosahexaenoic Acid Prevents Silica-Induced Development of Pulmonary Ectopic Germinal Centers and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse. Frontiers in Immunology, 9, article 2002.

Bates, M.A, Benninghoff, A., Gilley, K.N, Holian, A., Harkema, J.R, Pestka, J.J, (2019). Mapping of Dynamic Transcriptome Changes Associated with Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse. Frontiers in Immunology, doi: 10.3389/fimmu.2019.00632.

Battson ML, Lee DM, Li Puma LC, Ecton KE, Thomas KN, Febvre HP, Chicco AJ, Weir TL, Gentile CL. Gut microbiota regulates cardiac ischemic tolerance and aortic stiffness in obesity. American Journal of Physiology – Heart and Circulatory Physiology – in press.

Battson ML, Lee DM, Weir TL, Gentile CG (2018) The gut microbiota as a novel regulator of cardiovascular function and disease. Journal of Nutritional Biochemistry 56:1-15.

Brunt VE, Gioscia-Ryan RA, Richey JJ, Zigler MC, Cuevas LM, Gonzalez A, Vazquez-Baeza Y, Battson ML, Smithson AT, Gilley AD, Ackermann G, Neilson AP, Weir TL, Davy KP, Knight RL, Seals DR. (2019) Suppression of the gut microbiome ameliorates ate-related arterial dysfunction and oxidative stress in mice. J Physiol 597:2361-2378

Buckley, M.R., Terry, P.D., Kirkpatrick, S.S., Arnold, J.D., McNally, M.M., Grandas, O.H., Freeman, M.B., Goldman, M.H., Whelan, J., Mountain, D.J.H. (2019) Dietary Supplementation with Zyflamend Poly-Herbal Extracts and Fish Oil Inhibit Intimal Hyperplasia Development Following Vascular Intervention. Nutr. Res. 68:34-44.

Cam A., Oyirifi, A.B., Liu, Y., Haschek, W.M., Iwaniec, U.T., Turner, R.T., Engeseth, N.J. and Helferich, W.G. (2019) Thermally abused frying oil potentiates metastasis to lung in murine model of late-stage breast cancer. Cancer Prev. Res. 12:201-210.

Chen D, Cheng Y, Peng P, Liu J, Wang Y, Ma Y, Anderson E, Chen C, Chen P, Ruan R. (2019) Effects of intense pulsed light on Cronobacter sakazakii and Salmonella surrogate Enterococcus faecium inoculated in different powdered foods. Food Chem. 296:23-28.

Chen H, Peng L, Pérez de Nanclares M, Trudeau MP, Yao D, Cheng Z, Urriola PE, Mydland LT, Shurson GC, Overland M, Chen C. (2019) Identification of Sinapine-Derived Choline from a Rapeseed Diet as a Source of Serum Trimethylamine N-Oxide in Pigs. J Agric Food Chem. 67:7748.

 Chen D, Peng P, Zhou N, Cheng Y, Min M, Ma Y, Mao Q, Chen P, Chen C, Ruan R. (2019) Evaluation of Cronobacter sakazakii inactivation and physicochemical property changes of non-fat dry milk powder by cold atmospheric plasma. Food Chem. 290:270-276.

Chimimba, J., Pratt, R., Cuellar, M, Delgado, E. (2019) Quality parameters of Masa and Tortillas Produced from Blue Maize (Zea mays sp. mays) Landraces. Journal of Food Science, 84: 213-223.

Cox-York KC, Stoecker E, Hamm AK, Weir TL (2019) Chapter 15: Microbial Metabolites in Cancer Promotion or Prevention. pp. 317-346. In: Microbiome and Cancer (ed. Robertson ES). Springer International Publishing, Cham, Switzerland.

Cuj-Laines, R., Hernández-Santos, B., Reyes-Jaquez, D., Delgado, E., Juarez-Barrientos, J.M., Rodriguez-Miranda, J. (2018) Physicochemical properties of ready-to-eat extruded nixtamalized maize based snacks enriched with grasshopper. International Journal of Food Science & Technology. 53:1889-1895.  

Delgado, E., Valverde-Quiroz, L., Lopez D., Cooke P., Valles-Rosales D., Flores, N. (2019) Characterization of Soluble Glandless Cottonseed Meal Proteins Based on Electrophoresis, Functional Properties and Microscopic Structure. Journal of Food Science. Accepted for publication on July, 2019.

Erika del Castillo, Richard Meier, Mei Chung, Devin C. Koestler, Tsute Chen, Bruce J. Paster, Kevin P. Charpentier, Karl T. Kelsey, Jacques Izard, and Dominique S. Michaud.  (2019) The Microbiomes of Pancreatic and Duodenum Tissue Overlap and are Highly Subject Specific but Differ between Pancreatic Cancer and Non-Cancer Subjects Cancer Epidemiology, Biomarkers & Prevention 28(2):370-383.

Febvre HP, Rao S, Gindin M, Goodwin NM, Vivanco JS, Manter DK, Wallace TC, Weir TL. (2019) PHAGE: Effects of bacteriophage consumption on gut microbiota, inflammation, and lipid metabolism. Nutrients 11:666.

Fiecke C, Kurzer M, Chen C, Csallany A. (2019) The in Vivo Antioxidant Effects of Epigallocatechin-3-Gallate Consumption in Healthy Postmenopausal Women Measured by Urinary Excretion of Secondary Lipid Peroxidation Products. Food and Nutrition Sciences. 10:15-27.

Gentile CG and Weir TL (2018) The gut microbiota at the intersection of diet and health. Science 362:776-780.

Gindin M, Febvre HP, Rao S, Wallace TC, Weir TL. (2018) Bacteriophage for Gastrointestinal Health (PHAGE) Study: Evaluating the Safety and Tolerability of Supplemental Bacteriophage Consumption. Journal of the American College of Nutrition.  Doi: 10.1080/07315724.2018.1483783.

Guha, S., Majumder, K. (2019). Structural-features of Food-derived Bioactive Peptides with Anti-inflammatory Activity: A Brief Review. Journal of Food Biochemistry. 43:e12531.

Hamm AK and Weir TL (2019) Spent hops as a source of novel prenylflavonoids for human health. Acta Horticulturae 1236:75-84.

Havird JC, Noe GR, Link L, Torres A, Sloan DB, Chicco AJ.  (2019) Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function? Mitochondrion 49:1-11.

Hintze, K.J, Benninghoff, A., Cho, C.E, Ward, R.E, (2018). Modeling the Western diet for pre-clinical investigations. Advances in Nutrition, 9:263-271.

Jeon AB, Ackart DF, Li W, Jackson M, Melander RJ, Melander C, Abramovitch RB, Chicco AJ, Basaraba RJ, Obregón-Henao A. (2019) 2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain. Sci. Rep. 9(1):1513.

Kerry L Ivey, Andrew T Chan, Jacques Izard, Aedin Cassidy, Geraint B Rogers and Eric B Rimm. (2019) Role of dietary flavonoid compounds in driving patterns of microbial community assembly mBio. 10(5): e01205-19.

Kim, E., G.A. Wright, R.S. Zoh, B.S. Patil, G.K. Jayaprakasha, E.S. Callaway, I. Ivanov, N.D. Turner, R.S. Chapkin.  (2019)  Establishment of a multi-component dietary bioactive human equivalent dose to delete damaged Lgr5+ stem cells using a mouse colon tumor initiation model.  European Journal of Cancer Prevention 28:383-389.

Kundu, P., Korol, D.L., Bandara, S., Monaikul, S., Ondera, C.E., Helferich, W.G., Khan, I.A., Doerge, D.R. and Schantz, S.L. (2018) Licorice root components mimic estrogens in an object location task but not an object recognition task. Hormones and Behavior 103:97-106.

Kundu, P., Patel, S., Meling, D.D., Deal, K., Gao, L., Helferich, W.G. and Flaws, J.A. (2018) The effects of dietary levels of genistein on ovarian follicle number and gene expression. Reprod. Toxicol. 81:132-139.

Lee DM, Battson ML, Jarrell DK, Hou S, Ecton KE, Weir TL, Gentile CG (2018) SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the intestinal microbiota in type II diabetic mice. Cardiovascular Diabetology, 17:62.

Ma Y, Zhou W, Chen P, Urriola PE, Shurson GC, Ruan R, Chen C. (2019) Metabolomic Evaluation of Scenedesmus sp. as a Feed Ingredient Revealed Dose-Dependent Effects on Redox Balance, Intermediary and Microbial Metabolism in a Mouse Model. Nutrients 11:E1971.

 Madeen, E., Siddens, L.K., Uesugi, S., McQuistan, T., Corley, R.C., Smith, J., Waters, K.M., Tilton, S.C., Anderson, K.A., Ognibene, T., Turteltaub, K. and Williams, D.E. (2019) Toxicokinetics of Benzo[a]pyrene in Humans: Extensive Metabolism as Determined by UPLC-Accelerator Mass Spectrometry Following Oral Micro-Dosing. Toxicol. Appl. Pharmacology, 364:97-105.

Mine, Y., Jin., Y., Zhang, H., Majumder, K., Zeng, Y., Sakurai, T., Taniguchi, Y., Takagaki, R., Watanabe, H., Mitsuzumi, H. (2019). Therapeutic Effects of Isomaltodextrin in a BALB/c Mouse Model of Egg Allergy. Journal of Functional Foods. 55:305-311.

L.F. de Sousa Moraes, X. Sun, M. C. G. Peluzio, and M. J. Zhu. (2019). Anthocyanins /anthocyanidins and colorectal cancer: what is behind the scenes? Critical Reviews in Food Science and Nutrition. 59: 59-71.

Neil ES, McGinley JN, Fitzgerald VK, Lauck CA, Tabke JA, Streeter-McDonald MR, Broeckling CD, Weir TL, Foster MT, Thompson HJ. Common bean (Phaseolus vulgaris L.) consumption reduces fat accumulation in a polygenic mouse model of obesity. Nutrients (in press).

Nerurkar PV, Orias D, Soares N, Kumar M, Nerurkar VR. (2019) Momordica charantia (bitter melon) modulates adipose tissue inflammasome gene expression and adipose-gut inflammatory crosstalk in high-fat diet (HFD)-fed mice. J Nutr Biochem. 68:16-32.

Obeidat Y, Cheng M-H, Catandi G, Carnevale E, Chicco AJ, Chen T. (2019) Design of A Multi-Sensor Platform for Integrating Extracellular Acidification Rate with Multi-Metabolite Flux Measurement for Small Biological Samples. Biosensors and Bioelectronics 15;133:39-47

Obeidat Y, Catandi GD, Carnevale EC, Chicco AJ, DeMann A, Field S, Chen T. (2018) A Multi-Sensor System for Measuring Bovine Embryo Metabolism. Biosensors and Bioelectronics, 126:615-623.

Pennington ER, Sullivan EM, Fix A, Dadooc S, Zeczycki T, DeSantis A, Schlattner U, Chicco AJ, Brown DA, Shaik SR. (2018) Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. J Biol Chem 293(41):15933-15946.

Popova, M., Soboleva, T., Ayad, S., Benninghoff, A., Berreau, L., (2018). A Visible Light-activated Quinolone Carbon Monoxide-releasing Molecule: Prodrug and Albumin-assisted Delivery Enable Anti-cancer and Potent Anti-inflammatory Effects. Journal of the American Chemical Society, 140:9721–9729.

Reed, K.M., Mendoza, K.M., and Coulombe, R.A. (2019) Altered Gene Response to Aflatoxin B1 in the Spleens of Susceptible and Resistant Turkeys. Toxins Apr 28;11(5). doi: 10.3390/toxins11050242.

Reed, K.M., Mendoza, K.M., and Coulombe, R.A. (2019) Differential Transcriptome Responses to Aflatoxin B1 in the Cecal Tonsil of Susceptible and Resistant Turkeys. Toxins 11:1-19.

Reed, K.M., Mendoza, K.M., Abrahnte, Juan and Coulombe, R.A. (2018) Comparative Response of the Hepatic Transcriptomes of Domesticated and Wild Turkey to Aflatoxin B1. Toxins 10:1-24.

Rodriguez, D., Benninghoff, A., Aardema, N., Phatak, S., Hintze, K.J, (2019). Basal Diet Determined Long-Term Composition of the Gut Microbiome and Mouse Phenotype to a Greater Extent than Fecal Microbiome Transfer from Lean or Obese Human Donors. Nutrients. 11:1630.

Shah MS​, DeSantis TZ, Yamal JM, Weir TL,  Ryan EP,  Cope JL, Hollister EB. (2018) Re-purposing 16S rRNA gene sequence data for within-case paired tumor, tumor-adjacent biopsy, and fecal samples to identify reproducible microbial markers for colorectal cancer. PLoS One https://doi.org/10.1371/journal.pone.0207002.

Soboleva, T., Esquer, H.J, Anderson, S.N, Berreau, L., Benninghoff, A., (2018). Mitochondrial-Localized Versus Cytosolic Intracellular CO-Releasing Organic PhotoCORMs: Evaluation of CO Effects Using Bioenergetics. ACS Chemical Biology, doi: 10.1021/acschembio.8b00387.

Soderborg TK, Mulligan CE, Clark SE. Babcock L, Janssen RC, Lemas DL, Johnson LK, Frank DN, Weir TL, Barbour LA, Hernandez TL, Kuhn KA, D’Alessandro A, El Kasim KC, Friedman JE (2018) The Gut Microbiota in Infants of Obese Mothers Increases Hepatic Inflammation and Susceptibility to Obesity and NAFLD in Germ-free Mice. Nature Communications 9:4462.

Song, H., Hughes, J.R., Turner, R.T., Iwaniec, U.T., Doerge, D.R. and Helferich, W.G. (2019) (±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth. Food Chem. Toxicol. 28:110970.

Stull VJ, Finer E, Bergmans RS, Febvre HP, Longhurst C, Manter DK, Patz J, Weir TL. (2018) Impact of Edible Cricket Consumption and Gut Microbiota in Healthy Adults, a Double-blind Crossover Trial. Scientific Reports 8, 10762

Wang, H., S. Zhang, Q. Shen, and M. J. Zhu. (2019) A metabolome explanation on beneficial effects of dietary Goji on intestine inflammation. Journal of Functional Food, 53:109-114.

Xing, T., Y. Kang, X. Xu, B. Wang, M. Du, and M. J. Zhu. (2018). Raspberry supplementation improves insulin signaling and promotes brown-like adipocyte development in white adipose tissue of obese mice. Molecular Nutrition and Food Research. 62:1701035.

Xing, L., Zhang, H., Majumder, K., Zhang, W., Mine, Y. (2019). γ‑Glutamylvaline Prevents Low-Grade Chronic Inflammation via Activation of a Calcium-Sensing Receptor Pathway in 3T3-L1 Mouse Adipocytes. Journal of Agricultural and Food Chemistry. 67 (30):8361-8369.

 Xue, Y., M. Du, and M. J. Zhu. (2019). Raspberry extract prevents Escherichia coli O157:H7-induced NLRP3 inflammasome activation. Journal of Functional Food. 56: 224-231.

Xue, Y., M. Du, and M. J. Zhu. (2019). Quercetin prevents Escherichia coli O157:H7 adhesion to epithelial cells by suppressing focal adhesions. Frontier in Microbiology. 9: 3278.

Yu, L., Wang, L., Mao, C., Duraki, D., Kim, J.E., Huang, R., Helferich, W.G., Nelson, D.R., Park, B.H. and Shapiro, D.J. (2019) Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations. Cancer Lett. 442:373-382.

Zhang, Z. Garzotto, M., Davis, E.W. II, Mori, M., Stoller, W.A., Farris, P.E., Wong, C.P., Beaver, L.M., Thomas, G.V., Williams, D.E., Dashwood, R.H., Hendrix, D.A., Ho, E. and Shannon, J. (2019) Sulforaphane bioavailability and chemopreventive activity in men presenting for biopsy of the prostate gland: a randomized control trial. Nutr. Cancer Jun 1:1-14.

Zhang, S, Wang, H., and M. J. Zhu. (2019). A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples. Talanta,196: 249-254.

Zhao, L., B. Wang, N. Gomez, J. Deavila, M. J. Zhu, and M. Du. (2019). Even a low dose of tamoxifen profoundly induces adipose tissue browning in female mice. International Journal of Obesity, in press.

Zhou Y, Zhang N, Arikawa AY, Chen C. (2019) Inhibitory Effects of Green Tea Polyphenols on Microbial Metabolism of Aromatic Amino Acids in Humans Revealed by Metabolomic Analysis. Metabolites 9:96.

Zhu, M.J., Kang, Y., Xue, Y., Liang, X., Garcia, M.P.G., Rodgers, D., Kagel, D.R., Du, M. (2018) Red raspberries suppress NLRP3 inflammasome and attenuate metabolic abnormalities in diet-induced obese mice. Journal of Nutritional Biochemistry 53, 96-103.

Zou, T., Wang, B., Yang, Q., de Avila, J.M., Zhu, M.J., You, J., Chen, D., Du, M. (2018) Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) alpha1. Journal of Nutritional Biochemistry 55, 157-164.

 

01/26/2021

There were 71 new publications by W4122 members in 2019-2020 period, addressing the effects of bioactive nutrients on health and chronic disease risk, basic insights into nutrient metabolism, and the development of new methodology and technologies for studying these processes in humans and biological model systems.  Publcations are listed below with W4122 group members in boldfaced text.

Riley L. Hughes, Mary E. Kable, Maria L. Marco, Nancy L. Keim, 2019. The role of the gut microbiome in predicting response to diet and the development of precision nutrition models. Part II: Results. Advances in Nutrition. Nov 1;10(6):979-998.

Solomon A. Mekonnen, Daniel Merenstein, Claire M. Fraser, and Maria L. Marco. 2020. Molecular mechanisms of probiotic prevention of antibiotic-associated diarrhea. Current Opinion in Biotechnology. 61:226-234

Zachary A. Bendiks, Knud E.B. Knudsen, Michael J. Keenan, and Maria L. Marco. 2020. Conserved and variable responses of the gut microbiome to resistant starch type 2. Nutrition Research. 77:12-28. doi: 10.1016/j.nutres.2020.02.009

Derrick Risner, Maria L. Marco, Sara A. Pace, and Edward S. Spang. 2020. The potential production of the bioactive compound pinene using whey permeate. Processes. 8(3), 263

Paraiso IL, Revel JS, Choi J, Miranda CL, Lak P, Kioussi C, Bobe G, Gombart AF, Raber J, Maier CS, Stevens JF. Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice. Mol Nutr Food Res. 2020 Aug;64(15):e2000341. doi: 10.1002/mnfr.202000341. Epub 2020 Jul 6. PMID: 32627931.

Logan IE, Bobe G, Miranda CL, Vasquez-Perez S, Choi J, Lowry MB, Sharpton TJ, Morgun A, Maier CS, Stevens JF, Shulzhenko N, Gombart AF. Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia. Microorganisms. 2020 Apr 5;8(4):520. doi:10.3390/microorganisms8040520. PMID: 32260528; PMCID: PMC7232377.

Zhang Y, Bobe G, Revel JS, Rodrigues RR, Sharpton TJ, Fantacone ML, Raslan K, Miranda CL, Lowry MB, Blakemore PR, Morgun A, Shulzhenko N, Maier CS, Stevens JF, Gombart AF. Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism. Mol Nutr Food Res. 2020 Jan;64(1):e1900789. doi: 10.1002/mnfr.201900789. Epub 2019 Dec 15. PMID: 31755244; PMCID: PMC7029812.

Matthews DG, Caruso M, Alcazar Magana A, Wright KM, Maier CS, Stevens JF, Gray NE, Quinn JF, Soumyanath A. Caffeoylquinic Acids in Centella Asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer's Disease Model Mice. Nutrients. 2020 Nov 13;12(11):3488. doi: 10.3390/nu12113488. PMID: 33202902; PMCID: PMC7698091.

Wright KM, Magana AA, Laethem RM, Moseley CL, Banks TT, Maier CS, Stevens JF, Quinn JF, Soumyanath A. Centella asiatica Water Extract Shows Low Potential for Cytochrome P450-Mediated Drug Interactions. Drug Metab Dispos. 2020 Oct;48(10):1053-1063. doi: 10.1124/dmd.120.090860. Epub 2020 Jun 24. PMID: 32581050; PMCID: PMC7543484.

Alcazar Magana A, Wright K, Vaswani A, Caruso M, Reed RL, Bailey CF, Nguyen T, Gray NE, Soumyanath A, Quinn J, Stevens JF, Maier CS. Integration of mass spectral fingerprinting analysis with precursor ion (MS1) quantification for the characterisation of botanical extracts: application to extracts of Centella asiatica (L.) Urban. Phytochem Anal. 2020 Nov;31(6):722-738. doi: 10.1002/pca.2936. Epub 2020 Apr 12. PMID: 32281154; PMCID: PMC7587007.

Selamassakul O, Laohakunjit N, Kerdchoechuen O, Yang L, Maier CS. Bioactive  peptides from brown rice protein hydrolyzed by bromelain: Relationship between biofunctional activities and flavor characteristics. J Food Sci. 2020 Mar;85(3):707-717. doi: 10.1111/1750-3841.15052. Epub 2020 Feb 11. PMID: 32043604.

Song Z, Pearce MC, Jiang Y, Yang L, Goodall C, Miranda CL, Milovancev M, Bracha S, Kolluri SK, Maier CS. Delineation of hypoxia-induced proteome shifts in osteosarcoma cells with different metastatic propensities. Sci Rep. 2020 Jan 20;10(1):727. doi: 10.1038/s41598-019-56878-x. PMID: 31959767; PMCID: PMC6971036.

Preston GW, Yang L, Phillips DH, Maier CS. Visualisation tools for dependent peptide searches to support the exploration of in vitro protein modifications. PLoS One. 2020 Jul 8;15(7):e0235263. doi: 10.1371/journal.pone.0235263. PMID: 32639981; PMCID: PMC7343161.

Magana AA, Reed RL, Koluda R, Miranda CL, Maier CS, Stevens JF. Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts. Antioxidants (Basel). 2020 Mar 5;9(3):217. doi: 10.3390/antiox9030217. PMID: 32150984; PMCID: PMC7139526.

Maruthamuthu, M.K., Raffiee, A.H., De Oliveira, D.M., Ardekani, A.M.,, Verma, M.S. (2020) Raman spectra-based deep learning – a tool to identify microbial contamination MicrobiologyOpen (in press).

Yildirim, A., Grant, J.C., Siamak, S.E., Lee, W., Maruthamuthu, M.K., Verma, M., Sutherland, J.W., Cakmak, M. (2020) Roll‐to‐Roll (R2R) Production of Large‐Area High‐Performance Piezoelectric Films Based on Vertically Aligned Nanocolumn Forests Advanced Materials Technologies. DOI: 10.1002/admt.202000553.

Maruthamuthu, M.K., Rudge, S.R., Ardekani, A.M., Ladisch, M.R., Verma, M.S. (2020) Process Analytical Technologies and Data Analytics for Manufacture of Monoclonal Antibodies Trends in Biotechnology. DOI: 10.1016/j.tibtech.2020.07.004.

Waimin, J.F.,§ Nejati, S.,§ Jiang, H., Qiu, J., Wang, J., Verma, M.S., Rahimi, R. (2020) Smart Capsule for Non-invasive Sampling and Studying of the Gastrointestinal Microbiome RSC Advances; 10: 16313-16322. DOI: 10.1039/C9RA10986B

Zhao D, Yuan B, Kshatriya D, Polyak A, Simon JE, Bello NT, Wu Q. Influence of Diet-Induced Obesity on the Bioavailability and Metabolism of Raspberry Ketone (4-(4-Hydroxyphenyl)-2-Butanone) in Mice. Mol Nutr Food Res. 2020 Apr;64(8):e1900907. doi: 10.1002/mnfr.201900907. Epub 2020 Feb 25. PMID: 32052560; PMCID: PMC7329366.

Yuan B, Zhao D, Kshatriya D, Bello NT, Simon JE, Wu Q. UHPLC-QqQ-MS/MS method development and validation with statistical analysis: Determination of raspberry ketone metabolites in mice plasma and brain. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Jul 15;1149:122146. doi: 10.1016/j.jchromb.2020.122146. Epub 2020 May 19. PMID: 32474352; PMCID: PMC7391222.

Kshatriya D, Hao L, Li X, Bello NT. Raspberry Ketone [4-(4-Hydroxyphenyl)-2-Butanone] Differentially Effects Meal Patterns and Cardiovascular Parameters in Mice. Nutrients. 2020 Jun 11;12(6):1754. doi: 10.3390/nu12061754. PMID: 32545402; PMCID: PMC7353175.

Hao L, Kshatriya D, Li X, Badrinath A, Szmacinski Z, Goedken MJ, Polunas M, Bello NT. Acute feeding suppression and toxicity of raspberry ketone [4-(4-hydroxyphenyl)-2-butanone] in mice. Food Chem Toxicol. 2020 Sep;143:111512. doi: 10.1016/j.fct.2020.111512. Epub 2020 Jun 19. PMID: 32565406; PMCID: PMC7483346.

Wang Y, Miller JW, Bello NT, Shapses SA. Low-vitamin-D diet lowers cerebral serotonin concentration in mature female mice. Nutrition Research. 2020 Sep;81:71-80. doi: 10.1016/j.nutres.2020.07.006. Epub 2020 Jul 24. PMID: 32920521.

Muthuraj PG, Natarajan, SK. Fetal Programming in Maternal Obesity. Diabesity 2020; 6(3): 36-39. DOI:10.15562/diabesity.2020.71 Review

Thoene M, Van Ormer M, Lyden E, Thompson M, Yuil-Valdes A, Natarajan SK, Mukherjee M, Nordgren TM, Furtado, Anderson-Berry A, Hanson C, Snowden J. Inflammatory Compounds and Fat-Soluble Nutrients in Mother-Infant Dyads at Time of Delivery. Pediatr Res (2020). In Press

Liu B, Lu Y, Chen X, Muthuraj PG, Li X, Pattabiraman M, Zempleni J, Kachman SD, Natarajan SK, Yu J. Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice. Nutrients. 2020 Feb 13;12(2):477. doi: 10.3390/nu12020477. PMID: 32069862.

Thoene M, VanOrmer M, Yuil-Valdes AG, Bruett T, Natarajan SK, Mukherjee M, Thompson M, Nordgren TM, Lippevelde WV, Overby, NC, Adu-Bonsaffoh K, Anderson-Berry A, Hanson C. Fat-Soluble Nutrients and Omega-3 Fatty Acids as Modifiable Factors Influencing Preterm Birth Risk. Placenta. 2020 Sep 1; 98:38-42. doi: 10.1016/j.placenta.2019.12.002. PMID: 33039030.

Ulu A, Sahoo PK, Yuil-Valdes AG, Mukherjee M, VanOrmer M, Muthuraj PG, Thompson M, Anderson-Berry A, Hanson CK, Natarajan SK*, Nordgren TM*. Omega-3 fatty acid-derived resolving D2 regulates human placental vascular smooth muscle and extravillous trophoblast activities. Int. J. Mol. Sci. 2019 Sep 7;20(18):4402. doi: 10.3390/ijms20184402. PMID: 31500240. *Co-corresponding author.

Johnson SA, Prenni J, Heuberger AL, Isweiri H, Chaparro J, Newman S, Uchanski M, Omerigic H, Michell K, Bunning M, Foster MT, Thompson HJ, Weir TL. Comprehensive Evaluation of Metabolites and Minerals in Six Microgreen Species and the Influence of Maturity. Current Development in Nutrition (in press)

Weir TL, McGinley JN, Neil ES, Thompson HJ (2020) Effect of pulse consumption on obesity and the metagenome, Proceedings of the 1st International Conference on Nutrients- Nutrition and Microbiota Effects on Chronic Disease. doi:10.3390/IECN2020-07009

Soderborg TK, Carpenter C, Janssen RC, Weir TL, Young BE, Krebs NF, Hernandez TL, Barbour LA, Frank DN, Kroehl, M, Friedman JE. (2020) Gestational diabetes is uniquely associated with altered early seeding of the infant gut microbiota. Front Endocrinol doi:10.3389/fendo.2020.603021

Grubb DS, Wrigley SD, Freedman KE, Wei Y, Vazquez AR, Trotter RE, Wallace TC, Johnson SA and Weir TL (2020) PHAGE-2 Study: Supplemental Bacteriophages Extend Bifidobacterium animalis subsp. lactis BL04 Benefits on Gut Health and Microbiota. Nutrients 12, 2474; doi:10.3390/nu12082474

Weir TL, Trikha SRJ, Thompson HJ (2020) Diet and Risk of Cancer Reduction: The Role of Diet-Microbiota Interactions and Microbial Metabolites. Seminars in Cancer Biology DOI: 10.1016/ j.semcancer.2020.06.007

Trotter RE, Vazquez AR, Grubb D, Freedman KE, Wei Y, Jones S, Gentile CL, Melby CL, Johnson SA, Weir TL (2020) Examining the Impact of Probiotic Supplement Intake on Endothelial Function and Lipid Metabolism in Healthy Adults. Beneficial Microbes 11 (7): 621-630.

Lee DM, Ecton K, Trikha SR, Wrigley SD, Thomas K, Battson M, Wei Y, Johnson SA, Weir TL, and Gentile CL. (2020) Microbial Metabolite Indole-3-Propionic Acid Supplementation Does Not Protect Mice from the Cardiometabolic Consequences of a Western Diet. Am J Physiol-Gastro Liver Physiol doi.org/10.1152/ajpgi.00375.2019

Hobbs JM, Vazquez AR, Remijan ND, Trotter RE, McMillan TV, Freedman K, Wei Y, Arnold OR, Wolfe LM, Johnson SA, and Weir TL (2020) Evaluation of Pharmacokinetics and Acute Anti-Inflammatory Potential of Two Oral Cannabidiol (CBD)Preparations. Phytotherapy Research DOI:10.1002/ptr.6651

Michell KA*, Isweiri H, Newman SE, Bunning M, Bellows LM, Dinges ME*, Grabos LE*, Rao S, Foster MT, Heuberger AL, Prenni JE, Thompson HJ, Uchanski ME, Weir TL, Johnson SA (2020) Microgreens for the Masses: Exploring Consumer Acceptance and Sensory Perceptions of an Emerging Functional Food Crop. Journal of Food Science

McGinley JN, Fitzgerald VK, Neil ES, Omerigic HM, Heuberger AL, Weir TL, McGee R, Vandermark G, Thompson HJ. (2020) Pulse Crop Effects on the Gut Microbial Populations, Intestinal Function, and Adiposity in a Mouse Model of Dietary Induced Obesity. Nutrients 12:593; doi: 10.3390/nu12030593

Thompson HJ, McGinley JN, Neil ES, Weir TL. (2020) Effect of common bean consumption on the gut associated microbiome in an in vivo screening model for breast cancer. Proceedings of the 1st International Conference on Nutrients-Nutrition and Microbiota Effects on Chronic Disease. doi: 10.3390/IECN2020-07008.

Puckett, D.L., Alani, D.S., Chahed, S., Frankel, V.D., Alquraishi, M., Donohoe, D.R., Voy, B.H., Whelan, J., and Bettaieb, A. 2020. The cross-talk between PKA and JNK mediates the anti-adipogenic potential of Zyflamend, a unique herbal blend. Adipocyte 9:454-471. (doi:10.1080/21623945.2020.1803642)

Puckett, D.L., Chahed, S., Alani, D.S., Donohoe, D.R., Whelan, J., and Bettaieb, A. 2020.  Zyflamend Induces Apoptosis in Pancreatic Cancer Cells via Modulation of the JNK Pathway. Cell Commun Signal. 18:126. (doi:10.1186/s12964-020-00609-7).

Whelan, J., 2020. Allometric scaling of dietary bioactives in metabolic research: The Present and Future. In: Nutritional Signaling Pathway Activities. In the series: Obesity and Diabetes Food Chemistry, Function and Analysis No. 24, Ed: Zhiyong Cheng, Royal Society of Chemistry, Chapter 11 (www.rsc.org), Pp. 295-309. (doi.org/10.1039/9781839160608).

Whelan, J., 2020. Conversion of dietary polyunsaturated fats between humans and rodents: A review of allometric scaling models. Prostaglandins Leukot Essent Fatty Acids 158:July 2020, 102094 (doi.org/10.1016/j.plefa.2020.102094).

Hung YT, Hu, Q, Faris RJ, Guo J, Urriola PE, Shurson GC, Chen C, Saqui-Salces M. Analysis of gastrointestinal responses revealed both shared and specific targets of zinc oxide and carbadox in weaned pigs. Antibiotics  9: 463 (2020)

Yuan J, Kerr BJ, Curry SM, Chen C, Identification of C9-C11 unsaturated aldehydes as prediction markers of growth and feed intake for non-ruminant animals fed oxidized soybean oil. J Anim Sci Biotechnol. 11: 49 (2020)

Chen D, Wiertzema JR, Peng P, Cheng Y, Wang Y, Liu J, Ma Y, Mosher W, Kang M, Min M, Chen P, Baumler DJ, Chen C, Lee L, Vickers Z, Feirtag J, Ruan R. Catalytic intense pulse light inactivation of Cronobacter sakazakii and other pathogens in non-fat dry milk and wheat flour. Food Chem. 332:127420 (2020)

Fritsch J, Garces L, Quintero MA, Pignac-Kobinger J, Santander AM, Fernández I, Ban YJ, Kwon D, Phillips MC, Knight K, Mao Q, Santaolalla R, Chen XS, Maruthamuthu M, Solis N, Damas OM, Kerman DH, Deshpande AR, Lewis JE, Chen C, Abreu MT, Low-fat, High-fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 20: S1542-3565 (2020)

Sathe AG, Tuite P, Chen C, Ma Y, Chen W, Cloyd J, Low WC, Steer CJ, Lee BY, Zhu XH, Coles LD, Pharmacokinetics, Safety, and Tolerability of Orally Administered Ursodeoxycholic Acid in Patients With Parkinson's Disease—A Pilot Study, J Clin Pharmacol. 60: 744-750 (2020)

Cui W, Sathyanarayan A, Lopresti M, Aghajan M, Chen C, Mashek DG. Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis. Autophagy. 19: 1-16 (2020)

An J, Liu J, Liang Y, Ma Y, Chen C, Cheng Y, Peng P, Zhou N, Zhang R, Addy M, Chen P, Liu Y, Huang G, Ren D, Ruan R. Characterization, bioavailability and protective effects of phenolic-rich extracts from almond hulls against pro-oxidant induced toxicity in Caco-2 cells. Food Chem. 322:126742 (2020)

Nerurkar PV*, Orias D, Soares N, Kumar M, Nerurkar VR. (2019) Momordica charantia (bitter melon) modulates adipose tissue inflammasome gene expression and adipose-gut inflammatory crosstalk in high-fat diet (HFD)-fed mice. J Nutr Biochem. 2019 Jun;68:16-32. doi: 10.1016/j.jnutbio.2019.03.003. Epub 2019 Mar 23. PMID: 31005847

Kar, A., Wei, X., Majumder, K., Eskridge, K., Handa, A., Subbiah, J. (2020). Effect of traditional and radiofrequency assisted thermal processing on the gel firmness of egg white powder. LWT-Food Science and Technology, 133: 110091.

Guha, S., Paul, C., Alvarez, S., Mine., Y., Majumder, K*. (2020). Dietary γ-glutamyl valine (γ-EV) ameliorates TNF-α induced vascular inflammation via endothelial calcium-sensing receptor (CaSR). Journal of Agricultural and Food Chemistry, 68: 9139.

Mine, Y., Majumder, K., Jin, Y., Zheng, Y. (2020). Chinese Sweet Tea (Rubus suavissimus) Polyphenols Attenuate the Allergic Responses in a BALB/C Mouse Model of Egg Allergy. Journal of Functional Foods, 67: 103827.

Kanouchi, K., Majumder, K., Shibata, H., Mine, Y. (2020). Lactobacillus pentosus S-PT84 and Rubus suavissimus leaf extract suppress lipopolysaccharide-induced gut permeability and egg allergen uptake. Food Production, Processing and Nutrition, 2:4.

Majumder, K., Jin, Y., Shibata, H., Mine, Y. (2020). Oral Intervention of Lactobacillus pentosus S-PT84 Attenuates the Allergenic Responses in a BALB/C Mouse Model of Egg Allergy. Molecular Immunology, 120: 43-51.

Jacques Izard, Teklu Kuru Gerbaba, and Shara R.P. Yumul. Three-dimensional printing of human microbiome constituents to understand spatial relationships and shape parameters in bacteriology, The American Biology Teacher - In press

Shajan Peter, Amanda Pendergraft, William VanDerPol, C. Mel Wilcox, Kondal R Kyanam Kabir Baig, Casey Morrow, Jacques Izard, Peter J. Mannon. Mucosa-associated microbiota in Barrett’s esophagus, dysplasia and esophageal adenocarcinoma differ similarly compared with healthy controls. Clinical and Translational Gastroenterology (2020) vol. 11(8) p e00199

Long H. Nguyen, Wenjie Ma, Dong D. Wang , Yin Cao, Himel Mallick, Teklu Gerbaba, Jason Lloyd-Price, Galeb Abu-Ali, A. Brantley Hall , Daniel Sikavi, David A.Drew, Raaj S. Mehta, Cesar Arze, Amit D. Joshi, Yan Yan, Tobyn Branck, Casey DuLong, Kerry Ivey, Shuji Ogino, Eric B. Rimm EB, Mingyang Song, Wendy S. Garrett, Jacques Izard, Curtis Huttenhower*, Andrew T. Chan. Association between sulfur-metabolizing bacterial communities in stool and risk of distal colorectal cancer in men. Gastroenterology (2020) vol. 158 (5) pp. 1313-1325 [Journal cover]

Rojas-Barboza D*, Park E,* Sassenfeld R, Winder J, Smith GB, Valles-Rosales D,  Delgado E,  Park YH. 2020. Rapid, Simple, Low-Cost Fluorescence Detection of Escherichia coli Using 3D-Printed Smartphone-Based Device. International Journal of Agricultural and Biological Engineering. Accepted for publication August 2020.

Matthews, A.*, Ulery, A., Rogus, S., Phillips, G., Delgado E. 2020. Heavy metal content of produce grown in San Juan County (New Mexico, USA). Journal of Environmental Science and Health, Part B. Published online. https://doi.org/10.1080/03601234.2020.1794220.

Delgado E, Gamero-Barraza G*, Flores-Rosas W, Valles-Rosales DJ, Medrano-Roldán H, Reyes-Jáquez D. 2020. Effect of lipids content and process parameters on the physicochemical, rheological, calorimetric and structural properties of an extruded canine food. Animal Nutrition and Feed Technology, 19, 455-469. DOI: 10.5958/0974-181X.2019.00042.8.

Flores N, Delgado E, Walker S, Rojas-Contreras J*, Pámanes-Carrasco G*. 2020. Effect of water stress on functional and marketable properties of roasted Big Jim chili pepper (Capsicum annum L.) in Southern USA. Acta Agricola y Pecuaria, 6(1), 1-8.

Quintero JQ*, Velazquez V*, Corrales-García LL, Torres JD, Delgado E, Ciro G, Rojas J. 2020. Use of plant proteins as microencapsulating agents of bioactive compounds extracted from annatto seeds (Bixa orellana L.). Antioxidants, 9(4), 310. https://doi.org/10.3390/antiox9040310

Ordoñez‐Quintana, E*., Salmeron, I., Chavez‐Flores, D., Ramos, V., Gutierrez, N., Morales‐Oyervides, L., Delgado, E., Kwofie, E., Ngadi, M., Perez‐Vega, S.B. 2020. Supercritical and subcritical extraction of ursolic acid and polyphenols from apple pomace: Effect of variables on composition and antioxidant capacity. Journal of Food Processing and Preservation, 44(1), e14296. https://doi.org/10.1111/jfpp.14296maize based snacks enriched with grasshopper. International Journal of Food Science & Technology, 53, 1889-1895. DOI:10.1111/ijfs.13774.

Melissa M. Melough, Shaowei Wu, Charles Eaton, Abrar A. Qureshi, Ock K. Chun, Eunyoung Cho. Citrus Consumption and Risk of Cutaneous Malignant Melanoma in the Women’s Health Initiative. Nutr Cancer. 2020;72(4):568-575. doi:10.1080/01635581.2019.1644353.

Weiyi Sun, Megan S. Rice, Min Kyung Park, Ock K. Chun, Melissa M. Melough, Hongmei Nan, Wenqing Li, Abrar A. Qureshi, Eunyoung Cho. Intake of Furocoumarins and Risk of Skin Cancer in Two Prospective US Cohort Studies. J Nutr. 2020;00:1–10.  https://doi.org/10.1093/jn/nxaa062

Evans R, Engelhorn HJ, Winger QA, Chicco AJ, Bouma GJ. A multiplex PCR genotyping assay to distinguish XX and XY tissues in sheep. Mol Biol Rep in press. PMID:  32743776

Haugen Frenkel JD, Ackart DF, Todd AK, DiLisio JE, Hoffman S, Tanner S, Kiran D, Murray M, Chicco AJ, Obregon-Henao A, Podell B, Basaraba R. Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis. Sci Rep in press

Le CH, Benage LG, Specht KS, Li Puma LA, Mulligan CM, Heuberger AL, Prenni JE, Claypool SM, Chatfield KC, Sparagna GC, Chicco AJ. Tafazzin deficiency impairs CoA-dependent oxidative metabolism in cardiac mitochondria. J Biol Chem, 295(35):12485-12497, 2020. PMID:  32665401

Li Puma LC, Hedges M, Heckman JM, Mathias AB, Engstrom MR, Brown AB, Chicco AJ. Experimental oxygen concentration influences rates of mitochondrial hydrogen peroxide release from cardiac and skeletal muscle preparations. Am J Physiol Reg Integr Comp Physiol, 318(5):R972-R980, 2020. PMID: 32233925

 

12/12/2021

There were 86 new publications by W4122 members in 2020-2021 reporting period, addressing the effects of bioactive nutrients on health and chronic disease risk, basic insights into nutrient metabolism, and the development of new methodology and technologies for studying these processes in humans and model systems.  Publications are listed below with W4122 group members in boldfaced text.

  1. Trikha SRJ, Lee DM, Ecton KA, Wrigley SD, Vazquez AR, Litwin NS, Thomas KN, Battson ML, Johnson SA, Kuhn KA, Colgan SP, Gentile CG, Weir TL (2021) Vascular Dysfunction and Glucose Intolerance are Transferrable to Germ Free Mice via an Obesity-Associated Human Microbiota. Gut Microbes 13(1): 1940791. IF: 10.245
  2. Freedman KE, Hill JL, Wei Y, Vazquez AR, Grubb DS, Trotter RE, Wrigley SD, Johnson SA, Foster MT, Weir TL (2021) Examining the immunomodulatory effects of novel probiotic Bacillus subtilis DE111. J. Mol. Sci. 22, 2453. https://doi.org/10.3390/ijms22052453 IF: 5.923
  3. Williams NNB, Ewell TR, Abbotts KSS, Harms KJ, Woelfel KA, Dooley GP, Weir TL, Bell C (2021) Comparison of five oral cannabidiol preparations in adult humans: Pharmacokinetics, body composition, and heart rate variability. Pharmaceuticals 14, 35. doi: 10.3390/ph14010035. IF: 6.321
  4. Johnson SA, Prenni J, Heuberger AL, Isweiri H, Chaparro J, Newman S, Uchanski M, Omerigic H, Michell K, Bunning M, Foster MT, Thompson HJ, Weir TL (2020) Comprehensive Evaluation of Metabolites and Minerals in Six Microgreen Species and the Influence of Maturity. Curr Dev Nutr nzaa180, doi: 10.1093/cdn/nzaa180
  5. Soderborg TK, Carpenter C, Janssen RC, Weir TL, Young BE, Krebs NF, Hernandez TL, Barbour LA, Frank DN, Kroehl M, Friedman JE. (2020) Gestational diabetes is uniquely associated with altered early seeding of the infant gut microbiota. Front Endocrinol doi:10.3389/fendo.2020.603021 IF: 3.675
  6. Grubb DS, Wrigley SD, Freedman KE, Wei Y, Vazquez AR, Trotter RE, Wallace TC, Johnson SA and Weir TL (2020) PHAGE-2 Study: Supplemental Bacteriophages Extend Bifidobacterium animalis subsp. lactis BL04 Benefits on Gut Health and Microbiota. Nutrients 12, 2474; doi.org/10.3390/nu12082474 IF:5.717
  7. Weir TL, Trikha SRJ, Thompson HJ (2020) Diet and Risk of Cancer Reduction: The Role of Diet-Microbiota Interactions and Microbial Metabolites. Seminars in Cancer Biology DOI: 10.1016/ j.semcancer.2020.06.007 IF:15.707
  8. Trotter RE, Vazquez AR, Grubb DS, Freedman KE, Wei Y, Jones S, Gentile CL, Melby CL, Johnson SA, Weir TL (2020) Examining the Impact of Probiotic Supplement Intake on Endothelial Function and Lipid Metabolism in Healthy Adults. Beneficial Microbes 11 (7): 621-630. IF: 4.205
  9. Lee DM, Ecton KE, Trikha SRJ, Wrigley SD, Thomas KN, Battson ML, Wei Y, Johnson SA, Weir TL, and Gentile CL (2020) Microbial Metabolite Indole-3-Propionic Acid Supplementation Does Not Protect Mice from the Cardiometabolic Consequences of a Western Diet. Am J Physiol-Gastro Liver Physiolorg/10.1152/ajpgi.00375.2019 IF: 4.052
  10. Bermúdez-Quiñones, G., Ochoa-Martinez, A., Gallegos-Infante, J.A., Rutiaga-Quiñones, O.M., Lara-Ceniceros T., Delgado, E., Gonzalez-Herrea, S.M. 2021. Synbiotic microcapsules using agavins and inulin as wall materials for Lactobacillus casei and Bifidobacterium breve: Viability, physicochemical properties, and resistance to in vitro oro-gastrointestinal transit. Journal of Food Processing and Preservation. Accepted for publication October,
  11. Delgado E., Valles-Rosales D. J., Pámanes-Carrasco G. A., Cooke P., Flores N. C., Reyes-Jáquez D. 2021. Structural, rheological, and calorimetric properties of an extruded shrimp feed using glandless cottonseed meal as a protein source. Journal of Aquaculture Research and Development 12(3), 627. Impact factor 1.27.
  12. Delgado, E., Alvarado-González*, Ó., Medrano-Roldán, H., Rodríguez-Miranda, J., Carrete-Carreón, F., Reyes-Jáquez, D. 2021. Evaluation of fish oil content and cottonseed meal with ultralow gossypol content on the functional properties of an extruded shrimp feed. Aquaculture Reports 19, 1-6. https://doi.org/10.1016/j.aqrep.2021.100588. Impact factor 2.289.
  13. Velazquez-Martinez, V., Valles-Rosales, D., Rodriguez-Uribe, L., Holguin, O., Quintero-Quiroz, J., Reyes-Jaquez, D., Rodriguez-Borbon, M.I., Villagrán-Villegas, L.Y., Delgado, E. 2021. Antimicrobial, shelf-life stability, and effect of maltodextrin and gum arabic on the encapsulation efficiency of sugarcane bagasse bioactive compounds. Foods 10(1), 115, https://doi.org/10.3390/foods10010116. Impact factor: 4.092.
  14. Whelan, J., 2021. Allometric scaling of dietary bioactives in metabolic research: The Present and Future. In: Nutritional Signaling Pathway Activities. In the series: Obesity and Diabetes Food Chemistry, Function and Analysis No. 24, Ed: Zhiyong Cheng, Royal Society of Chemistry, Chapter 11, Pp. 295-309.
  15. Aardema, N.D, Rodriguez, D.M, Van Wettere, A., Benninghoff, A., Hintze, K.J, (2021). The Western Dietary Pattern Combined with Vancomycin-Mediated Changes to the Gut Microbiome Exacerbates Colitis Severity and Colon Tumorigenesis. Nutrients, 13:3, 881. doi: 10.3390/nu13030881
  16. Chauhan, S, Wagner, J.G, Benninghoff, A., Lewandowski, R.P, Favor, O.K, Wierenga, K.A, Gilley, K.N, Ross, E.A, Harakema, J.R, Pestka, J.J, (2021). Rapid Induction of Pulmonary Inflammation, Autoimmune Gene Expression, and Ectopic Lymphoid Neogenesis Following Acute Silica Exposure in Lupus-Prone Mice. Frontiers in Immunology, 12, 635138. doi: 10.3389/fimmu.2021.635138
  17. Rajasinghe, L.D, Li, Q.Z, Zhu, C., Yan, M., Chauhan, P.S, Wierenga, K.A, Bates, M.A, Harkema, J.R, Benninghoff, A., Pestka, J.J, (2020). Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice. Autoimmunity, 53:7, 415-433. doi: 10.1080/08916934.2020.1801651
  18. Wierenga, K.A, Strakovsky, R.S, Benninghoff, A., Rajasinghe, L.D, Lock, A.L, Harkema, J.R, Pestka, J.J, (2020). Requisite Omega-3 HUFA Biomarker Thresholds for Preventing Murine Lupus Flaring. Frontiers in Immunology, 11, 1796. doi: 10.3389/fimmu.2020.01796
  19. Gilley, K.N, Wierenga, K.A, Chauhuan, P.S, Wagner, J.G, Lewandowski, R.P, Ross, E.A, Lock, A.L, Harkema, J.R, Benninghoff, A., Pestka, J.J, (2020). Influence of total western diet on docosahexaenoic acid suppression of silica-triggered lupus flaring in NZBWF1 mice. Plos One, 15:5, e0233183. doi: 10.1371/journal.pone.0233183
  20. Benninghoff, A., Hintze, K.J, Monsanto, S., Rodriguez, D.M, Hunter, A., Phatak, S., Pestka, J.J, Van Wettere, A., Ward, R.E, (2020). Consumption of the total Western diet promotes colitis and inflammation-associated colorectal cancer in mice. Nutrients, 12:2, 544. doi: 10.3390/nu12020544
  21. Pascual-Garrigos, A., Maruthamuthu, M.K., Ault, A., Davidson, J., Rudakov, G., Pillai, D., Koziol, J., Schoonmaker, J., Johnson, T., Verma, M.S.* (Accepted: 3 September, 2021) On-farm colorimetric detection of Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni in crude bovine nasal samples. Veterinary Research
  22. Davidson, J.L., § Wang, J.W., § Maruthamuthu, M.K.,§ Dextre, A., Pascual-Garrigos, A., Mohan, S., Putikam, S.V.S., Osman, F.O.I., McChesney, D., Seville, J., Verma, M.S.* (2021) A paper-based colorimetric molecular test for SARS-CoV-2 in saliva. Biosensors and Bioelectronics: X; 9: 100076. DOI: 10.1016/j.biosx.2021.100076
  23. Mohan, S.,§ Pascual-Garrigos, A.,§ Brouwer, H., Pillai, D., Koziol, J., Ault, A., Schoonmaker, J., Johnson, T., Verma, M.S.* (2021) Loop-mediated isothermal amplification for the detection of Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni in bovine nasal samples. ACS Agricultural Science and Technology; 1: 100-108. DOI:10.1021/acsagscitech.0c00072
  24. Ma Y, Lu Y, Petrofsky K, Liu J, Cheng Y, Ruan R, Chen Double-edged metabolic effects from a short-term feeding of functionalized wheat bran in mouse revealed by metabolomic profiling. J Agric Food Chem. 69: 6543-6555 (2021)
  25. Peng L, Yuan J, Yao D, Chen Fingerprinting triacylglycerols and aldehydes as identity and thermal stability indicators of camellia oil through chemometric comparison with olive oil. Food Science and Nutrition. 9: 2561–2575 (2021)
  26. Mao Q, Liu J, Wiertzema JR, Chen D, Chen P, Baumler DJ, Ruan R, Chen Identification of Quinone Degradation as a Triggering Event for Intense Pulsed Light-Elicited Metabolic Changes in Escherichia coli by Metabolomic Fingerprinting. Metabolites. 11:102 (2021)
  27. Cui W, Sathyanarayan A, Lopresti M, Aghajan M, Chen C, Mashek DG. Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis. Autophagy 17, 690-705 (2021)
  28. Zhu XH, Lee BY, Tuite P, Coles L, Sathe AG, Chen C, Cloyd J, Low WC, Steer CJ, Chen W. Quantitative Assessment of Occipital Metabolic and Energetic Changes in Parkinson’s Patients, Using In Vivo 31P MRS-Based Metabolic Imaging at 7T. Metabolites. 11:145 (2021)
  29. Qiu X, Macchietto MG, Liu X, Lu Y, Ma Y, Guo H, Saqui-Salces M, Bernlohr DA, Chen C, Shen S, Chen X. Identification of gut microbiota and microbial metabolites regulated by an antimicrobial peptide lipocalin 2 in high fat diet-induced obesity. Int J Obes (Lond). 45:143-154 (2021)
  30. Chen D, Mosher W, Wiertzema J, Peng P, Min M, Cheng Y, An J, Ma Y, Fan X, Niemira BA, Baumler DJ, Chen C, Chen P, Ruan R. Effects of intense pulsed light and gamma irradiation on Bacillus cereus spores in mesquite pod flour. Food Chem. 344:128675 (2021)
  31. Fritsch J, Garces L, Quintero MA, Pignac-Kobinger J, Santander AM, Fernández I, Ban YJ, Kwon D, Phillips MC, Knight K, Mao Q, Santaolalla R, Chen XS, Maruthamuthu M, Solis N, Damas OM, Kerman DH, Deshpande AR, Lewis JE, Chen C, Abreu MT, Low-fat, High-fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 19: 1189-1199 (2021)
  32. Junichi R. Sakaki, Melissa M. Melough, Mary B. Roberts, Charles B. Eaton, Aladdin H. Shadyab, Abrar A. Qureshi, Ock K. Chun and Eunyoung Cho§. Citrus Consumption and Risk of Non-melanoma Skin Cancer in the Women’s Health Initiative. Cancers 2021, 13(9), 2173; https://doi.org/10.3390/cancers13092173. §Co-corresponding authors
  33. Melissa M. Melough, Shaowei Wu, Charles Eaton, Abrar A. Qureshi, Ock K. Chun, Eunyoung Cho§. Citrus Consumption and Risk of Cutaneous Malignant Melanoma in the Women’s Health Initiative. Nutr Cancer. 2020;72(4):568-575. doi:10.1080/01635581.2019.1644353.
  34. Co-corresponding authors
  35. Weiyi Sun, Megan S. Rice, Min Kyung Park, Ock K. Chun, Melissa M. Melough, Hongmei Nan, Wenqing Li, Abrar A. Qureshi, Eunyoung Cho. Intake of Furocoumarins and Risk of Skin Cancer in Two Prospective US Cohort Studies. J Nutr. 2020;00:1–10. https://doi.org/10.1093/jn/nxaa062.
  36. Long H. Nguyen*, Yin Cao*, Jinhee Hur, Raaj S. Mehta, Daniel R. Sikavi, Yiqing Wang, Wenjie Ma, Kana Wu, Mingyang Song, Edward L. Giovannucci, Eric B. Rimm, Walter C. Willett, Wendy S. Garrett, Jacques Izard, Curtis Huttenhower*, Andrew T. Chan*. The sulfur microbial diet is associated with risk of early-onset colorectal cancer precursors. Gastroenterology – In Press.
  37. Lisa A. Whisenhunt, Linda H. Xu*, Fan Yang*, and Jacques Izard. Output Consistency Scale to Standardize Ostomate Output Description in Clinical Practice and Studies. Academic Journal of Gastroenterology & Hepatology (2021) vol. 3(1) AJGH.MS.ID.000554
  38. Daniel R. Sikavi, Long H. Nguyen, Koichiro Haruki, Tomotaka Ugai, Wenjie Ma, Dong D. Wang, Kelsey Thompson, Yan Yan, Tobyn Branck, Jeremy Wilkinson, Naohiko Akimoto, Rong Zhong, Mai Chan Lau, Kosuke Mima, Keisuke Kosumi, Teppei Morikawa, Eric B. Rimm, Wendy S. Garrett, Jacques Izard, Yin Cao, Mingyang Song, Curtis Huttenhower, Shuji Ogino and Andrew T. Chan. The sulfur microbial diet and risk of colorectal cancer by molecular subtypes and intratumoral microbial species in adult men. Clinical and Translational Gastroenterology (2021), Vol. 12(8) p. e00338.
  39. Wenjie Ma, Long H. Nguyen, Mingyang Song, Daniel D. Wang, Eric Franzosa, Yin Cao, Amit Joshi, David A. Drew, Raaj Mehta, Kerry L. Ivey, Lisa L. Strate, Edward L. Giovannucci, Jacques Izard, Wendy Garrett, Eric B. Rimm, Curtis Huttenhower, and Andrew T. Chan. Dietary fiber intake, the gut microbiome, and chronic systemic inflammation in a cohort of adult men. Genome Medicine (2021), vol. 13, article 102.
  40. Christine Everett, Chengchen Li, Jeremy E. Wilkinson, Long Nguyen, Lauren McIver, Kerry Ivey, Jacques Izard, Natalia Palacios, A. Heather Eliassen, Walter C. Willett, Alberto Ascherio, Qi Sun, Shelley S. Tworoger, Andrew T. Chan, Wendy S. Garrett, Curtis Huttenhower, Eric B. Rimm, and Mingyang Song. Overview of the microbiome among Nurses study (Micro-N) as an example of prospective characterization of the microbiome within cohort studies. Nature Protocols (2021), Vol. 16, p. 2724-2731 (DOI: 10.1038/s41596-021-00519-z).
  41. Jacques Izard, Teklu Kuru Gerbaba, and Shara R.P. Yumul. Three-dimensional printing of human microbiome constituents to understand spatial relationships and shape parameters in bacteriology. The American Biology Teacher (2021), vol. 83 (3), p. 188-190.
  42. Mei Chung, Naisi Zhao, Richard Meier, Devin C. Koestler, Guojun Wu, Erika Del Castillo, Bruce J. Paster, Kevin Charpentier, Jacques Izard, Karl T. Kelsey, and Dominique S. Comparisons of oral, intestinal, and pancreatic bacterial microbiomes in patients with pancreatic cancer and other gastrointestinal diseases. Michaud Journal of Oral Microbiology (2021), vol. 83 (13) 1887680.
  43. Guha S^, Alvarez S, Mine Y, Majumder K*. (2021). Transport of Dietary Anti-Inflammatory Peptide, γ-Glutamyl Valine (γ-EV), across the Intestinal Caco-2 Monolayer. Nutrients, 13, 1448. doi: 10.3390/nu13051448.
  44. Nolasco E^, Yang J, Ciftci O, Vu CD, Alvarez S, Purdum, S, Majumder K*. (2021). Evaluating the Effect of Cooking and Gastrointestinal Digestion in Modulating the Bio-accessibility of Different Bioactive Compounds of Eggs. Food Chemistry, 344, 128623. doi: 10.1016/j.foodchem.2020.128623.
  45. Matthews DG, Caruso M, Alcazar Magana A, Wright KM, Maier CS, Stevens JF, Gray NE, Quinn JF, Soumyanath A. Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer's Disease Model Mice. Nutrients. 2020 Nov 13;12(11):3488. doi: 10.3390/nu12113488. PMID: 33202902
  46. Paraiso IL, Tran TQ, Magana AA, Kundu P, Choi J, Maier CS, Bobe G, Raber J, Kioussi C, Stevens JF. Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling. Front Pharmacol. 2021 Apr 20;12:643857. doi: 10.3389/fphar.2021.643857. eCollection 2021. PMID: 33959012
  47. Zhang Y, Bobe G, Miranda CL, Lowry MB, Hsu VL, Lohr CV, Wong CP, Jump DB, Robinson MM, Sharpton TJ, Maier CS, Stevens JF, Gombart AF. Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ. Elife. 2021 Jun 15;10:e66398. doi: 10.7554/eLife.66398. PMID: 34128467
  48. Alcázar Magaña A, Kamimura N, Soumyanath A, Stevens JF, Maier Caffeoylquinic acids: chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity. Plant J. 2021 Sep;107(5):1299-1319. doi: 10.1111/tpj.15390. Epub 2021 Jul 23. PMID: 34171156 Review.
  49. Logan IE, Shulzhenko N, Sharpton TJ, Bobe G, Liu K, Nuss S, Jones ML, Miranda CL, Vasquez-Perez S, Pennington JM, Leonard SW, Choi J, Wu W, Gurung M, Kim JP, Lowry MB, Morgun A, Maier CS, Stevens JF, Gombart AF. Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice. Mol Nutr Food Res. 2021 Sep 8:e2100389. doi: 10.1002/mnfr.202100389. Online ahead of print. PMID: 34496124.
  50. Yap ESP, Uthairatanakij A, Laohakunjit N, Jitareerat P, Vaswani A, Magana AA, Morre J, Maier Plant growth and metabolic changes in 'Super Hot' chili fruit (Capsicum annuum) exposed to supplemental LED lights. Plant Sci. 2021 Apr;305:110826. doi: 10.1016/j.plantsci.2021.110826. Epub 2021 Jan 14. PMID: 33691960
  51. Weinman MA, Ramsey SA, Leeper HJ, Brady JV, Schlueter A, Stanisheuski S, Maier CS, Miller T, Ruby CE, Bracha S. Exosomal proteomic signatures correlate with drug resistance and carboplatin treatment outcome in a spontaneous model of canine osteosarcoma. Cancer Cell Int. 2021 May 1;21(1):245. doi: 10.1186/s12935-021-01943-7.PMID: 33933069
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