02/05/2015

See attached Publications document for NC229's 2014 publications and funding.

02/06/2016

 

1. PERTINENT (SWINE VIROLOGY) PUBLICATIONS ISSUED OR “IN PRESS”

 

• Refereed publications

 

 

• Alonso C, Raynor P, Davies P, Torremorell M (2015). Evaluation of an electrostatic particle ionization technology for decreasing airborne pathogens in pigs. Aerobiologia (accepted).


• Alonso C, Raynor PC, Davies PR, Torremorell M (2015). Concentration, size distribution, and infectivity of airborne particles carrying swine viruses. PLoS One. 10(8):e0135675.


• Alvarez J, Torremorell M, Morrison R, Perez A (2015). Association of the presence of influenza A virus and porcine reproductive and respiratory syndrome virus in sow farms with post-weaning mortality. Prev Vet Med. pii: S0167-5877(15)00235-4. doi: 10.1016/j.prevetmed.2015.07.003.


• Alvarez J., Goede D., Morrison R., Perez A. (2015) Spatial and temporal epidemiology of porcine epidemic diarrhea (PED) in the Midwest and Southeast regions of the United States. Preventive Veterinary Medicine (in press)


• Alvarez J., Sarradell J., Morrison R., Perez A. (2015) Impact of porcine epidemic diarrhea on performance of growing pigs. PLoS One 10(3):e0120532.


• Anderson, T. K., Laegreid, W. W., Cerutti, F., Osorio, F. A., Nelson, E. A., Christopher-Hennings, J. and Goldberg, T. L. (2012). Ranking viruses: measures of positional importance within networks define core viruses for rational polyvalent vaccine development. Bioinformatics 28:1624-1632.


• Anderson, T.K., Campbell, B.A., Nelson, M.I., Lewis, N.S., Janas-Martindale, A., Killian, M., Vincent, A.L. 2015. Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance. Virus Research. 201:24–31.


• Arruda PHE, Stevenson GW, Mary KL, Burrough ER, Gauger PC, Harmon KM, Magstadt DR, Yoon K-J, Zhang J, Madson DM, Pineyro P, Derscheid RJ, Schwartz KJ, Cooper VL, Halbur PG, Main RG, Sato Y, Arruda BL. 2015. Natural outbreak of H5N2 highly pathogenic avian influenza virus in 2015 in two commercial layer facilities in Iowa: Lesions and viral antigen distribution. J Vet Diagn Invest (accepted)


• Bailey, A. L., M. Lauck, A. Weiler, S. D. Sibley, J. M. Dinis, Z. Bergman, C. W. Nelson, M. Correll, M. Gleicher, D. Hyeroba, A. Tumukunde, G. Weny, C. Chapman, J. H. Kuhn, A. L. Hughes, T. C. Friedrich, T. L. Goldberg and D. H. O'Connor (2014). High genetic diversity and adaptive potential of two simian hemorrhagic fever viruses in a wild primate population. PLoS One 9(3): e90714.


• Bailey, A. L., M. Lauck, M. Mohns, E. J. Peterson, K. Beheler, K. G. Brunner, K. Crosno, A. Mejia, J. Mutschler, M. Gehrke, J. Greene, A. J. Ericsen, A. Weiler, G. Lehrer-Brey, T. C. Friedrich, S. D. Sibley, E. G. Kallas, S. Capuano, 3rd, J. Rogers, T. L. Goldberg, H. A. Simmons and D. H. O'Connor (2015). Durable sequence stability and bone marrow tropism in a macaque model of human pegivirus infection. Sci Transl Med 7(305): 305ra144.


• Bailey, A. L., M. Lauck, S. D. Sibley, J. Pecotte, K. Rice, G. Weny, A. Tumukunde, D. Hyeroba, J. Greene, M. Correll, M. Gleicher, T. C. Friedrich, P. B. Jahrling, J. H. Kuhn, T. L. Goldberg, J. Rogers and D. H. O'Connor (2014). Two novel simian arteriviruses in captive and wild baboons (Papio spp.). J Virol 88(22): 13231-13239.


• Balka G, Wang X, Balint A, Kiss I, Olasz F, Banai K, Rusvai M, Stadejek T, Marthaler D, Murtaugh MP, Zadori Z. 2015. Full genome sequence analysis of a wild, non-MLV-related type 2 Hungarian PRRSV variant isolated in Europe. Virus Res. 200:1-8.


• Balzli, C.L., Lager, K.M., Vincent, A.L., Gauger, P, Brockmeier, S., Miller, L.C., Richt, J., Ma, W., Suarez, D.L., and Swayne, D.E. (2015). Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses. Influenza and Other Respiratory Viruses. In press.


• Baranovich, T., Bahl, J., Marathe, B. M., Culhane, M., Stigger-Rosser, E., Darnell, D., Kaplan, B. S., Lowe, J. F., Webby, R. J. & Govorkova, E. A. 2015. Influenza A viruses of swine circulating in the United States during 2009-2014 are susceptible to neuraminidase inhibitors but show lineage-dependent resistance to adamantanes. Antiviral Research. 117:10-19.


• Brar MS, Shi M, Murtaugh MP, Leung FC. 2015. Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 96:1570-1580.


• Butler, J.E., Lager, K.M., Golde, W., Faaberg, K.S., Sinkora, M., Loving, C., Zhang, Y.I. 2014. Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic. Immunologic Research. 59:81-108.


• Cai, Y., E. N. Postnikova, J. G. Bernbaum, S. Q. Yu, S. Mazur, N. M. Deiuliis, S. R. Radoshitzky, M. G. Lackemeyer, A. McCluskey, P. J. Robinson, V. Haucke, V. Wahl-Jensen, A. L. Bailey, M. Lauck, T. C. Friedrich, D. H. O'Connor, T. L. Goldberg, P. B. Jahrling and J. H. Kuhn (2015). Simian Hemorrhagic Fever Virus Cell Entry Is Dependent on CD163 and Uses a Clathrin-Mediated Endocytosis-Like Pathway. J Virol 89:844-856.


• Chattha KS, Roth JA, Saif LJ. 2015. Strategies for design and application of enteric viral vaccines. Annu Rev Anim Biosci 3:6.1–6.21


• Chen Q, Gauger P, Stafne M, Thomas J, Arruda P, Burrough E, Madson D, Brodie J, Magstadt D, Derscheid R, Welch M, Zhang J. 2015. Pathogenicity and pathogenesis of a United States porcine deltacoronavirus cell culture isolate in 5-day-old neonatal piglets. Virol 482:51-59


• Chen N, Dekkers JCM, Ewen CL, Rowland RRR. 2015. Porcine reproductive and respiratory syndrome virus replication and amino acid substitutions in pigs that lack adaptive immunity. Virus Res. 195:246-249.


• Cheung, A.K. 2015. Specific functions of the Rep and Rep' proteins of porcine circovirus during copy-release and rolling-circle DNA replication. Virol 481:43-50.


• Cheung, A.K., Ng, TF., Lager, K.M., Alt, D.P., Delwart, E., Pogranichniy, R.M. 2015. Identification of several clades of novel single-stranded circular DNA viruses with conserved stem-loop structures in pig feces. Arch Virol 160:353-358.


• Choi MJ, Torremorell M, Bender JB, Smith K, Boxrud D, Ertl JR&, Yang M, Suwannakarn K, Her D, Nguyen J, Uyeki TM, Levine M, Lindstrom S, Katz JM, Jhung M, Vetter S, Wong KK, Sreevatsan S, Lynfield R. 2015. Live animal markets in Minnesota: a potential source for emergence of novel influenza viruses and interspecies transmission. Clin Infect Dis. 61(9):1355-1362


• Kreikemeier CA¹, Engle TB, Lucot KL, Kachman SD, Burkey TE, Ciobanu DC. Genome-wide analysis of TNF-alpha response in pigs challenged with porcine circovirus 2b. Anim Genet. 2015; 46:205-208.


• Collin, E.A., S. Anbalagan, F. Okda, R. Batman, E.A. Nelson, B.M. Hause. 2015. An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs. BMC Vet Res 11:62.


• Constans M, Ssemadaali M, Kolyvushko O and Ramamoorthy S. Antigenic determinants of possible vaccine escape by porcine circovirus subtype 2b viruses. S. Bioinform Biol Insights. 2015; 9 (Suppl 2): 1–12.


• Crawford K, Lager K, Miller L, Opriessnig T, Gerber P, Hesse R. 2015. Evaluation of porcine epidemic diarrhea virus transmission and the immune response in growing pigs. Vet Res 46:49.


• Day DN, Sparks JW, Karriker LA, Stalder KJ, Wulf LW, Zhang J, Kinyon JM, Stock ML, Gehring R, Wang C, Ellingson J, Coetzee JF. 2015. Impact of an experimental PRRSV and Streptococcus suis coinfection on the pharmacokinetics of ceftiofur hydrochloride after intramuscular injection in pigs. J Vet Pharmacol Ther 38:475-481.


• Dee, S., C. Neill, T. Clement, A. Singrey, J. Hennings, E. Nelson. 2015. An evaluation of porcine epidemic diarrhea virus survival in individual feed ingredients in the presence or absence of a liquid antimicrobial. Porcine Health Management. 1:9.


• Alexander Postel, Lester J. Perez, Carmen L. Perera, Stefanie Schmeiser, Denise Meyer, Alexandra Meindl-Boehmer, Liliam Rios, Sophia Austermann-Busch, Maria T. Frias-Lepoureau, Paul Becher. Development of a new LAMP assay for the detection of CSFV. 2015. Arch Virol. DOI 10.1007/s00705-015-2407-1


• Diaz A, Enomoto S, Romagosa A, Sreevatsan S, Nelson M, Culhane M, Torremorell M (2015). Genome plasticity of triple reassortant H1N1 influenza A virus during infection of vaccinated pigs. J Gen Virol. doi: 10.1099/jgv.0.000258.


• Diaz A, Perez A, Sreevatsan S, Davies P, Culhane M, Torremorell M (2015). Association between influenza A virus infection and pigs subpopulations in endemically infected breeding herds. PLoS One, 10(6):e0129213.


• Dunkelberger, JR, NJ Boddicker, NVL Serão, JM Young, RRR Rowland and JCM Dekkers. 2015. Response of pigs divergently selected for residual feed intake to experimental infection with the PRRS virus. Livestock Sci. in press .


• Engle TB, Jobman EE, Moural TW, McKnite AM, Bundy JW, Barnes SY, Davis EH, Ewen, CL, AG Cino-Ozuna, H He, MA Kerrigan, JCM Dekkers, CK Tuggle, RRR Rowland, CR Wyatt. 2014. Analysis of blood leukocytes in a naturally occurring immunodeficiency of pigs shows the defect is localized to B and T cells. J Vet Immunol Immunopath (in press)


• Engle TB, Jobman EE, Moural TW, McKnite AM, Bundy JW, Barnes SY, Davis EH, Galeota JA, Burkey TE, Plastow GS, Kachman SD, Ciobanu DC. Variation in time and magnitude of immune response and viremia in experimental challenges with Porcine circovirus 2b. BMC Vet Res. 2014; 10:286.


• Gallardo C., Fernández-Pinero J., Pelayo V., Gazaev I., Markowska-Daniel I., Pridotkas G., Nieto R., Fernández-Pacheco P., Bokhan S., Nevolko O., Drozhzhe Zh., Pérez C., Soler A., Kolvasov D., Arias M. Genetic variation among African Swine Fever genotype II viruses, Eastern and Central Europe. Emerg Inf Dis 20 (9):1544-1547. doi: 10.3201/eid2009.140554


• Gauger, P.C., Loving, C.L., Khurana, S., Lorusso, A., Perez, D.R., Kehrli, Jr., M.E., Roth, J.A., Golding, H., Vincent, A.L. 2014. Live attenuated influenza A virus vaccine protects against A(H1N1)pdm09 heterologous challenge without vaccine associated enhanced respiratory disease. Virol 471-473:93-104.


• Gava, D., Souza, C.K., Schaefer, R., Vincent, A.L., Cantão, M.E., Coldebella, A., Ciacci-Zanella, J.R. 2015. A TaqMan-based real-time PCR for detection and quantification of porcine parvovirus 4. J Virol Method. 219:14–17.


• Gerber PF, Gong Q, Huang Y-W, Wang C, Holtkamp D, Opriessnig T. 2014. Detection of antibodies against porcine epidemic diarrhea virus in serum and colostrum by indirect ELISA. Vet J 202:33-36.


• Goede D, Murtaugh MP, Nerem J, Yeske P, Rossow K, Morrison R. 2015. Previous infection of sows with a “mild” strain of Porcine Epidemic Diarrhea Virus confers protection against infection with a “severe” strain. Vet Micro. 176:161-164.


• Goller K.V., Malogolovkin A.S., Katorkin S., Kolbasov D., Titov I., Höper D., Beer M., Keil G.M., Portugal R., Blome S. Tandem repeat insertion in African swine fever virus, Russia, 2012. Emerg Inf Dis. 2:731-732.


• Goodell CK, Zhang J, Strait E, Harmon K, Patnayak D, Otterson T, Culhane M, Christopher-Hennings J, Clement T, Leslie-Steen P, Hesse R, Anderson J, Skarbek K, Vincent A, Kitikoon P, Swenson S, Jenkings-Moore M, McGill J, Rauh R, Nelson W, O'Connell C, Shah R, Wang C, Main R, Zimmerman J. 2015. Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time, reverse transcription polymerase chain reaction and virus isolation. Can J Vet Res (in press).


• Harmon KM, Gauger PC, Zhang J, Piñeyro PE, Dunn DD, Chriswell AJ. 2015. Whole genome sequences of a novel porcine circovirus type 2 detected in swine from Mexico and the United States. Genome Announc (in press).


• Hause B, Collin EA, Peddireddi L, Yuan F, Chen Z, Hesse RA, Gauger PC, Clement T, Fang Y, Anderson G. 2015. Discovery of a novel putative atypical porcine pestivirus in pigs in the United States. J Gen Virol doi:10.1099/jgv.0.000251 (in press).


• Hause B, EA Collin, L Peddireddi, F Yuan, Z Chen, RA Hesse, P Gauger, T Clement, Y Fang, G Anderson. 2015. Discovery of a novel putative atypical porcine pestivirus in pigs in the United States. J. Gen. Virology. 96(10):2994-8.


• Henningson, J. N., Rajao, D. S., Kitikoon, P., Lorusso, A., Culhane, M. R., Lewis, N. S., Anderson, T. K. & Vincent, A. L. 2015. Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine. Vet Microbiol 176:40-49.


• Henningson, J.N., Rajao, D.S., Kitikoon, P., Lorusso, A., Culhane, M.R., Lewis, N.S., Anderson, T.K., Vincent, A.L. 2015. Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine. Veterinary Microbiology. 176(1-2):40-49.


• Hughes HR, Vincent AL, Brockmeier SL, Gauger PC, Pena L, Santos J, Braucher DR, Perez DR, Loving CL. 2015. Oral fluids as a live-animal sample for evaluating cross-reactivity and cross-protection following intranasal influenza A virus vaccination in pigs. Clin Vaccine Immunol doi:10.1128/CVI.00358-15.


• Iglesias I., Munoz M. J., Montes F., Perez A., Gogin A., Kolbasov D., de la Torre A. Reproductive ratio for the local spread of African Swine Fever in wild boars in the Russian Federation. Transboundary and Emerging Diseases. 02/2015, doi: 10.1111/tbed.12337


• Jaing, CJ, JB Thissen, SN Gardner, KS McLoughlin, P Hullinger PJ, N Monday, MC Niederwerder, RR Rowland. 2015. Application of a pathogen microarray for the analysis of viruses and bacteria in clinical diagnostic samples from pigs. J Vet Diagn Invest. 27:313-325.


• Jarvis MC, Lam HC, Zhang Y, Wang L, Hesse RA, Hause BM, Vlasova A, Wang Q, Zhang J, Nelson M, Murtaugh M, Marthaler D. 2015. Genomic and phylogenetic relationships between American and global strains of porcine epidemic diarrhea virus. Prev Vet Med (in press)


• Jiang YH, Xiao CT, Yin SH, Gerber PF, Halbur PG, Opriessnig T. 2014. High prevalence and genetic diversity of porcine bocaviruses in pigs in the USA and identification of multiple novel porcine bocaviruses. J Gen Virol 95:453-465.


• Jige Du, Xinna Ge, Ying Liu, Ping Jiang, Zhe Wang, Ruimin Zhang, Lei Zhou, Xin Guo, Jun Han, Hanchun Yang: Targeting swine SLA-I molecules for proteasomal degradation by the nsp1α replicase protein of the Chinese highly pathogenic PRRSV strain JXwn06. Journal of Virology 10/2015; DOI:10.1128/JVI.02307-15


• Kappes, M.A., Faaberg, K.S. 2015. PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity. Virology. 479-480C:475-486.


• Kappes, M.A., Miller, C.L., Faaberg, K.S. 2015. Porcine reproductive and respiratory syndrome virus nonstructural protein 2 (nsp2) topology and selective isoform integration in artificial membranes. Virology. 481:51-62.


• Kenney SP, and X.J. Meng. 2015. The SH3 Binding Domain within the Nucleocapsid Protein of Porcine Reproductive and Respiratory Syndrome Virus Interacts with Cellular Proteins STAMI, TXK, Fyn, Hck, and Cortactin. Virus Research. 204:31-39.


• Khatun A, Shabir N, Yoon K-J, Kim W-I. 2015. Effects of ribavirin on the replication and genetic stability of porcine reproductive and respiratory syndrome virus. BMC Vet Res 11:21.


• Khatun A, Shabir N, Seo B-J, Kim B-S, Yoon K-J, Kim W-I. 2015. High genetic stability of a ribavirin-resistant porcine reproductive and respiratory syndrome virus (PRRSV) during sequential passages in pigs. J Virol (accepted).


• Koltes, JE, E Fritz-Waters, CJ Eisley, I Choi, H Bao, A Kommadath, NV Serão, NJ Boddicker, SM Abrams, M Schroyen, H Loyd, CK Tuggle, GS Plastow, L Guan, P Stothard, JK Lunney, P Liu, S Carpenter, RR Rowland, JC Dekkers, JM Reecy. 2015. Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection.BMC Genomics. 16:412.


• Kuhn, J. H., M. Lauck, A. L. Bailey, A. M. Shchetinin, T. V. Vishnevskaya, Y. Bào, T. F. F. Ng, M. LeBreton, B. S. Schneider, A. Gillis, U. Tamoufe, J. L. D. Diffo, J. M. Takuo, N. O. Kondov, L. L. Coffey, N. D. Wolfe, E. Delwart, A. N. Clawson, E. Postnikova, L. Bollinger, M. G. Lackemeyer, S. R. Radoshitzky, G. Palacios, J. Wada, Z. V. Shevtsova, P. B. Jahrling, B. A. Lapin, P. G. Deriabin, M. Dunowska, S. V. Alkhovsky, J. Rogers, T. C. Friedrich, D. H. O’Connor and T. L. Goldberg (2015). Reorganization and expansion of the nidoviral family Arteriviridae. Archives of Virology: DOI 10.1007/s00705-00015-02672-z.


• Ladinig, A, SE Detmer, K Clarke, C Ashley, RRR Rowland, JK Lunney, JCS Harding. 2015. Pathogenicity of three type 2 Porcine Reproductive and Respiratory Syndrome virus strains in experimentally inoculated pregnant gilts. Virus Res 203:24-35.


• Lager, K.M., Schlink, S.N., Brockmeier, S.L., Miller, L.C., Henningson, J.N., Kappes, M.A., Kehrli, M.E., Loving, C.L., Guo, B., Swenson, S.L., Yang, H., Faaberg, K.S. 2014. Efficacy of type 2 PRRSV vaccine against Chinese and Vietnamese HP-PRRSV challenge in pigs. Vaccine. 32(48):6457–6462.


• Lauck, M., D. Hyeroba, A. Tumukunde, G. Weny, S. M. Lank, C. A. Chapman, D. H. O'Connor, T. C. Friedrich and T. L. Goldberg (2011). Novel, divergent simian hemorrhagic fever viruses in a wild Ugandan red colobus monkey discovered using direct pyrosequencing. PLoS One 6(4): e19056.


• Lauck, M., G. Palacios, M. R. Wiley, Y. L, Y. Fang, M. G. Lackemeyer, Y. Cai, A. L. Bailey, E. Postnikova, S. R. Radoshitzky, R. F. Johnson, S. V. Alkhovsky, P. G. Deriabin, T. C. Friedrich, T. L. Goldberg, P. B. Jahrling, D. H. O'Connor and J. H. Kuhn (2014). Genome Sequences of Simian Hemorrhagic Fever Virus Variant NIH LVR42-0/M6941 Isolates (Arteriviridae: Arterivirus). Genome Announc 2(5).


• Lauck, M., S. D. Sibley, D. Hyeroba, A. Tumukunde, G. Weny, C. A. Chapman, N. Ting, W. M. Switzer, J. H. Kuhn, T. C. Friedrich, D. H. O'Connor and T. L. Goldberg (2013). Exceptional simian hemorrhagic fever virus diversity in a wild African primate community. J Virol 87(1): 688-691.


• Lauck, M., S. V. Alkhovsky, Y. Bao, A. L. Bailey, Z. V. Shevtsova, A. M. Shchetinin, T. V. Vishnevskaya, M. G. Lackemeyer, E. Postnikova, S. Mazur, J. Wada, S. R. Radoshitzky, T. C. Friedrich, B. A. Lapin, P. G. Deriabin, P. B. Jahrling, T. L. Goldberg, D. H. O'Connor and J. H. Kuhn (2015). Historical outbreaks of simian hemorrhagic fever in captive macaques were caused by distinct arteriviruses. J Virol 89(15): 8082-8087.


• Lei Zhou, Zichun Wang, Yuping Ding, Xinna Ge, Xin Guo, Hanchun Yang: NADC30-like Strain of Porcine Reproductive and Respiratory Syndrome Virus, China. Emerging infectious diseases 12/2015; 21(12). DOI:10.3201/eid2112.150360


• Li J, Murtaugh MP. 2015. Functional analysis of Porcine reproductive and respiratory syndrome virus N-glycans in infection of permissive cells. Virology. 477:82-88.


• Li J, Tao S, Orlando R, Murtaugh MP. 2015. N-glycosylation profiling of Porcine reproductive and respiratory syndrome virus envelope glycoprotein 5. Virology 478:82-88. Featured on Virology Highlights http://www.virologyhighlights.com/?p=547


• Li Y, Tas A, Sun Z, Snijder EJ, Fang Y. 2015. Proteolytic Processing of Porcine Reproductive and Respiratory Syndrome Virus Replicase ORF1a Polyprotein. Virus Research, 111(21):E2172-81.


• Linhares DCL, Johnson C, Morrison, RB. 2015. Economic analysis of vaccination strategies for PRRS control. PLOS One (in press).


• Lomakina N.F, Shustova E.Y, Strizhakova O.M, Drexler J.F, Lukashev A.N. Epizootic of vesicular disease in pigs caused by coxsackievirus B4 in USSR in 1975. The Journal of General Virology, 10/2015, doi: 10.1099/jgv.0.000318.


• Lorusso, A., Ciacci-Zanella, J.R., Zanella, E.L., Pena, L., Perez, D.R., Lager, K.M., Rajao, D.S., Loving, C.L., Kitikoon, P., Vincent, A.L. 2014. Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine. Journal of General Virology. 95(Pt 12):2618-2626.


• Loving CL, Osorio FA, Murtaugh MP, Zuckermann FA.(2015) Innate and adaptive immunity against Porcine Reproductive and Respiratory Syndrome Virus. Vet Immunol Immunopathol. 2015 Sep 15;167(1-2):1-14. (Review) PMID: 26209116


• Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E. 2014. Cross-fostering to prevent maternal cell transfer did not prevent vaccine-associated enhanced respiratory disease that occurred following heterologous influenza challenge of pigs vaccinated in presence of maternal immunity. Viral Immunology. 27(7):334-342.


• Lunney JK, Fang Y, Ladinig A, Chen N, Li Y, Rowland B, Renukaradhya GJ. 2015. Porcine reproductive and respiratory syndrome virus (PRRSV): Pathogenesis and Interaction with the Immune System. Review article in press for publishing on Volume 4 of the Annual Review of Animal Biosciences.


• Madson D, Magstadt D, Arruda P, Hoang H, Sun D, Bower L, Bhandari M, Burrough E, Gauger P, Pillatzki A, Stevenson G, Wilberts B, Brodie J, Harmon K, Wang C, Main R, Zhang J, Yoon K-J. 2014. Pathogenesis of porcine epidemic diarrhea virus isolate (US/Iowa/18984/2013) in 3-week-old weaned pigs. Vet Microbiol 74:60-68.


• Madson DM, Arruda PHE, Magstadt DR, Burrough ER, Hoang H, Sun D, Labios LP, Bhandari M, Gauger PC, Stevenson GW, Wilberts BL, Wang C, Zhang J, Yoon KJ. 2015. Characterization of porcine epidemic diarrhea virus isolate US/Iowa/18984/2013 infection in one-day-old caesarian derived colostrum deprived (CDCD) neonatal piglets. Vet Pathol doi: 10.1177/0300985815591080.


• Malogolovkin A., Burmakina G., Tulman E.R., Delhon G., Diel D.G., Salnikov N., Kutish G.F., Kolbasov D., Rock D.L. African swine fever virus CD2v and C-type lectin gene loci mediate serological specificity. J Gen Virol. 04/2015;96; P. 866-73, doi: 10.1099/jgv.0.000024.


• McCarty M, Petznick T, Kuster C, Bower L, Zhang J, Yoon KJ, Madson D. 2015. Case report describing the clinical course of porcine epidemic diarrhea in a commercial boar stud and return of the stud to service after whole-herd inoculation with porcine epidemic diarrhea virus. J Swine Health Prod 23:264-271.


• McCormick K, Z Jiang, L Zhu, SR Lawson, R Langenhorst, R Ransburgh, C Brunick, R J Webby, V Huber, and Y Fang. 2015. Construction and immunogenicity evaluation of recombinant influenza A viruses containing chimeric hemagglutinin genes derived from genetically divergent influenza H1N1 viruses. PLoS One. 10(6):e0127649.


• Miller, L.C., Crawford, K., Lager, K.M., Kellner, S.G., Brockmeier, S.M. (2015). Evaluation of a real-time polymerase chain reaction assay for porcine epidemic diarrhea virus surveillance purposes. Journal of Veterinary Diagnostic Investigation. In press.


• Miller, L.C., Harhay, G.P., Bayles, D.O., Zanella, E.L., and Lager, K.M. (2015). Effects of pseudorabies virus infection on the tracheobronchial lymph node transcriptome. Bioinformatics and Biology Insights. In press.


• Molecular epidemiology studies of swine influenza virus revealing a reassorted virus H1N1 in swine farms in Cuba. 2015. Preventive Veterinary Medicine HTTP://dx.doi.org/10.1016/j.prevetmed.2015. 02.013


• Murthy AM, Y.Y. Ni, X.J. Meng, and C. Zhang. 2015. Production and evaluation of virus-like particles displaying immunogenic epitopes of porcine reproductive and respiratory syndrome virus (PRRSV). International Journal of Molecular Sciences. 16(4):8382-96.


• Neira V, Rabinowitz P, Rendahl A, Paccha B, Gibbs SG, Torremorell M (2015). Characterization of viral load, viability and persistence of influenza A virus in air and on surfaces of swine production facilities. PlosOne, Submitted for publication.


• Nelson MI, Culhane MR, Rovira A, Torremorell M, Guerrero P, Norambuena J (2015). Novel human-like influenza A viruses circulate in swine in Mexico and Chile. PLOS Currents: Outbreaks. Edition 1. doi: 10.1371/currents.outbreaks.c8b3207c9bad98474eca3013fa933ca6.


• Nelson, M. I., Viboud, C., Vincent, A. L., Culhane, M. R., Detmer, S. E., Wentworth, D. E., Rambaut, A., Suchard, M. A., Holmes, E. C. & Lemey, P. 2015. Global migration of influenza A viruses in swine. Nature Communications. 6:6696.


• Nelson, M.I., Stratton, J., Killian, M.L, Janas-Martindale, A., Vincent, A.L. 2015. Continual reintroduction of human pandemic H1N1 influenza A viruses into swine in the United States, 2009-2014. Journal of Virology. 89(12):6218-6226.


• Nelson, M.I., Viboud, C., Vincent, A.L., Culhane, M.R., Detmer, S.E., Wentworth, D.E., Rambaut, A., Suchard, M.A., Holmes, E.C., Lemey, P. 2015. Global migration of influenza A viruses in swine. Nature Communications. 6:6696. Log No. 308670


• Nelson, M.I., Vincent, A.L. 2015. Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface. Trends in Microbiology. 23(3):142-153.


• Nelson, M.I., Wentworth, D.E., Culhane, M.R., Vincent, A.L., Viboud, C., LaPointe, M.P., Lin, X., Holmes, E.C., Detmer, S.E. 2014. Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations. Journal of Virology. 88(17):10110-10119.


• Niederwerder, MC, B Bhupinder , NVL Serão, BR Trible, MA Kerrigan, JK Lunney, JCM Dekkers, RRR Rowland. Vaccination with a porcine reproductive and respiratory syndrome (PRRS) modified live virus vaccine followed by challenge with PRRSV and porcine circovirus type 2 (PCV2) protects against PRRS but enhances PCV2 replication and pathogenesis when compared to non-vaccinated co-challenged controls. J Clin Vacc Immunol. In Press.


• Okda, F., X. Liu, A. Singrey, T. Clement, J. Nelson, J. Christopher-Hennings, E.A. Nelson, S. Lawson. 2015. Development of an indirect ELISA, blocking ELISA, fluorescent microsphere immunoassay and fluorescent focus neutralization assay for serologic evaluation of exposure to North American strains of Porcine Epidemic Diarrhea Virus. BMC Vet. Res. 11:180. Doi:10.1186/s12917-015-0500-z.


• Opriessnig T, Xiao CT, Gerber PF, Halbur PG, Matzinger SR, Meng XJ. 2014. Mutant USA strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarean-derived, colostrum-deprived pigs. J Gen Virol 95:2495-2503.


• Opriessnig T, Xiao CT, Gerber PF, Halbur PG. 2014. Identification of recently described porcine parvoviruses in archived North American samples from 1996 and association with porcine circovirus associated disease. Vet Microbiol 173:9-16.


• Paccha B, Jones RM, Gibbs S, Kane MJ, Torremorell M, Neira-Ramirez V, Rabinowitz PM (2015). Modeling risk of occupational zoonotic influenza infection in swine workers. J of Occupational Environmental Hygiene, Submitted for publication.


• Paccha B, Neira-Ramirez V, Gibbs S, Torremorell M, Rabinowitz P (2015). Swine worker precautions during suspected outbreaks of influenza in swine. J of Environmental Health, Accepted for publication.


• Palinski RM, Chen Z, Henningson JN, Lang Y, Rowland RR, Fang Y, Prickett J, Gauger PC, Hause BM. 2015. Widespread detection and characterization of porcine parainfluenza virus 1 in pigs in the United States. J. Gen. Virol. 2015 Nov 17. doi: 10.1099/jgv.0.000343. [Epub ahead of print]


• Panyasing Y, Goodell CK, Kittawornrat A, Wang C, Levis I; Desfresne L, Rauh R, Gauger PC, Zhang J, Lin K, Azeem S, Ghorbani-Nezami S, Yoon K-J, Zimmerman J. 2015. Influenza A virus surveillance based on pre-weaning piglet oral fluid samples. Transbound Emerg Dis DOI: 10.1111/tbed.12307 (in press).


• Pepin B, Liu F, Main R, Ramirez A, Zimmerman J. 2015. Collection of oral fluids from individually-housed sows. J Swine Health Prod 23:35-37.


• Pepin BJ, Kittawornrat A, Liu F, Gauger PC, Harmon K, Abate S, Main R, Garton C, Hargrove J, Rademacher C, Ramirez A, Zimmerman J. 2015. Comparison of specimens for detection of porcine reproductive and respiratory syndrome virus infection in boar studs. Transbound Emerg Dis 62:295-304.


• Perez AM, Davies PR, Goodell CK, Holtkamp DJ, Mondaca-Fernandez E, Poljak Z, Tousignant SJ, Valdes-Donoso P, Zimmerman JJ, Morrison RB. 2015. Lessons learned and knowledge gaps about the epidemiology and control of porcine reproductive and respiratory syndrome virus in North America. J Am Vet Med Assoc 246:1304-1317.


• Peters BM, Krantz SA, Holtkamp DJ, Wang C, Galina Pantoja L. 2015. Assessment of colostrum management strategies at commercial sow farms using immunocrit ratios. J Swine Health Prod (In Press)


• Pillatzki AE, Gauger PC, Madson DM, Burrough ER, Zhang J, Chen Q, Magstadt DR, Arruda PHE, Stevenson GW, Yoon KJ. 2015. Experimental inoculation of neonatal pigs with porcine epidemic diarrhea virus (PEDV) -contaminated feed. J Swine Health Prod 23:317-320.


• Piñeyro PE, Kenney SP, Giménez-Lirola LG, Heffron CL, Matzinger SR, Opriessnig T, and X.J. Meng. 2015. Expression of antigenic epitopes of porcine reproductive and respiratory syndrome virus (PRRSV) in a modified live-attenuated porcine circovirus type 2 (PCV2) vaccine virus (PCV1-2a) as a potential bivalent vaccine against both PCV2 and PRRSV. Virus Research. 210:154-164.


• Piñeyro PE, Kenney SP, Giménez-Lirola LG, Heffron CL, Matzinger SR, Opriessnig T, Meng XJ. 2015. Expression of antigenic epitopes of porcine reproductive and respiratory syndrome virus (PRRSV) in a modified live-attenuated porcine circovirus type 2 (PCV2) vaccine virus (PCV1-2a) as a potential bivalent vaccine against both PCV2 and PRRSV. Virus Res 210:154-164.


• Piñeyro PE, Kenney SP, Gimenez-Lirola LG, Opriessnig T, Tian D, Heffron CL, and X.J. Meng. 2015. Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus. Virus Research. 2015 Nov 7. pii: S0168-1702(15)30112-X. doi: 10.1016/j.virusres.2015.11.005.


• Piñeyro PE, Kenney SP, Giménez-Lirola LG, Opriessnig T, Tian D, Heffron CL, Meng XJ. 2015. Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus. Virus Res doi:10.1016/j.virusres.2015.11.005.


• Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications. 2015. Sara Muñoz-González, Nicolas Ruggli, Rosa Rosell, Lester Josué Pérez, Maria Teresa Frías-Leuporeau, Lorenzo Fraile, Maria Montoya, Lorena Cordoba, Mariano Domingo, Felix Ehrensperger, Artur Summerfield, Llilianne Ganges. PLOS ONE | DOI:10.1371/journal.pone.0125692


• Qing He, Yan Li, Lei Zhou, Xinna Ge, Xin Guo, Hanchun Yang: Both Nsp1β and Nsp11 are responsible for differential TNF-α production induced by porcine reproductive and respiratory syndrome virus strains with different pathogenicity in vitro. Virus Research 02/2015; 201. DOI:10.1016/j.virusres.2015.02.014


• Rajao DS, Gauger P, Anderson TK, Lewis NS, Abente EJ, Killian ML, Zhang J, Vincent AL. 2015. Novel human-like swine H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct. J Virol 89:11213-11222.


• Rajao, D.S., Anderson, T.K., Gauger, P.C., Vincent, A.L. 2014. Pathogenesis and vaccination of influenza A virus in swine. In: Compans, R.W., Oldstone, M.B.A., editors. Influenza Pathogenesis and Control, Current Topics in Microbiology and Immunology. Switzerland: Springer International Publishing. p. 307-326.


• Rajão, D.S., Loving, C.L., Gauger, P.C., Kitikoon, P., Vincent, A.L. 2014. Influenza A virus hemagglutinin protein subunit vaccine elicits vaccine-associated enhanced respiratory disease. Vaccine. 32(40):5170-5176.


• Rajao, D.S., Vincent, A.L. 2015. Swine as a model for influenza A virus infection and immunity. ILAR Journal. 56(1):44-52.


• Ran, Z., H. Shen, Y. Lang, E. Kolb, N. Turan, L. Zhu, J. Ma, B. Bawa, Q. Liu, H. Liu, M. Quast, G. Sexton, F. Krammer, B. Hause, J. Christopher-Hennings, E. Nelson, J. Richt, F. Li, and W. Ma. 2015. Domestic pigs are susceptible to infection with influenza B viruses. Journal of Virology 89:4818-4826.


• Renukaradhya G, Ouyang K, Shyu D, Dhakal S, Binjawadagi B, Guo R, Ransburgh R, Bondra K M, Gauger P, Zhang J, Specht T, Gilbertie A, Minton W, Fang Y, Lakshmanappa Y. 2015. Evaluation of humoral immune status in porcine epidemic diarrhea virus (PEDV) infected sows under field conditions. Accepted, Veterinary Research


• Renukaradhya GJ, Meng XJ, Clavert JG, Roof M, and Lager KM. 2015. Live porcine reproductive and respiratory syndrome virus vaccines: Current status and future direction. Vaccine. 2015;33(33):4069-80.


• Renukaradhya GJ, Meng XJ, Clavert JG, Roof M, and Lager KM. Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: Current status and future direction. Vaccine. 33(27):3065-3072.


• Renukaradhya, G.J., B, Narasimhan, S.K. Mallapragada (2015). Respiratory nanoparticle-based vaccines and challenges associated with animal models and translation, J Control Release (In Press). Vergne, C. Guinat, P. Petkova, A. Gogin, D. Kolbasov, S. Blome, S. Molia, J. Pinto Ferreira, B. Wieland, H. Nathues and D. U. Pfeiffer. Attitudes and beliefs of pig farmers and wild boar hunters towards reporting of African Swine Fever in Bulgaria, Germany and the western part of the Russian Federation. Transboundary and Emerging Diseases, 08/2014, doi: 10.1111/tbed.12254


• Renukaradhya, G.J., Meng, X.J., Calvert, J.G., Roof, M., Lager, K.M. 2015. Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: Current status and future direction. Vaccine. 33(27):3065-3072.


• Renukaradhya, G.J., X-J, Meng, J.G. Calvert, M. Roof, and K.M. Lager (2015). Live porcine reproductive and respiratory syndrome virus-based vaccines: current status and future direction. Vaccine, 33:4069-4080. PMID: 26148878


• Renukaradhya, G.J., X-J, Meng, J.G. Calvert, M. Roof, K.M. Lager (2015). Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: Current status and future direction. Vaccine, 33(27):3065-3072. PMID: 25980425


• Richmond O, Cecere TE, Erdogan E, Meng XJ, Piñeyro P, Subramaniam S, Todd SM, LeRoith T. PD-L1 expression is increased in monocyte derived dendritic cells in response to porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus infections. Vet Immunol Immunopathol 168:24-29.


• Richmond O, Cecere TE, Erdogan E, Meng XJ, Piñeyro P, Subramaniam S, Todd SM, LeRoith T. The PD-L1/CD86 ratio is increased in dendritic cells co-infected with porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus, and the PD-L1/PD-1 axis is associated with anergy, apoptosis, and the induction of regulatory T-cells in porcine lymphocytes. Vet Microbiol 180:223-229.


• Richmond O, T.E. Cecere, E. Edrogan, X.J. Meng, P. Piñeyro, S. Subramaniam, S.M. Todd, and T. LeRoith. 2015. PD-L1 expression is increased in monocyte derived dendritic cells in response to porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus infections. Veterinary Immunology and Immunopathology. 168(1-2):24-9.


• Richmond O, T.E. Cecere, E. Erdogan, X.J. Meng, P. Pineyro, S. Subramaniam, S.M Todd, T. LeRoith. 2015. The PD-L1/CD86 ratio is increased in dendritic cells co-infected with porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus, and the PD-L1/PD-1 axis is associated with anergy, apoptosis, and the induction of regulatory T-cells in porcine lymphocytes. Veterinary Microbiology. 180(3-4):223-9.


• Robinson SR, Li J, Nelson EA, Murtaugh MP. 2015. Broadly neutralizing antibodies against the rapidly evolving porcine reproductive and respiratory syndrome virus. Virus Res. 203:56-65.


• Robinson, S., J. Li, E.A. Nelson, M.P. Murtaugh. Broadly neutralizing antibodies against the rapidly evolving Porcine reproductive and respiratory syndrome virus. Virus Research 203:56-65.


• Sandbulte MR, Rovid-Spickler A, Zaabel P, Roth JA. 2015. Optimal use of vaccines for control of Influenza A virus in swine. Vaccines 3:22-73.


• Sang, Y., Miller, L.C., Blecha, F. 2015. Macrophage polarization in virus-host interactions. Journal of Clinical & Cellular Immunology. 6:2.


• Sasaki Y., Alvarez J., Sekiguchi S., Sueyoshi M., Otake S., Perez A. Epidemiological factors associated to spread of porcine epidemic diarrhea in Japan. Preventive Veterinary Medicine (in press)


• Schneider PT, Zhang J, Ramirez A, Wang C, Holtkamp DJ. 2015. Evaluation of disinfection protocols to reduce virus transmission via livestock transport vehicles using model trailers in experimental conditions. J Swine Health Prod 23:306-316.


• Schroyen, M, JP Steibel, JE Koltes, I Choi, NE Raney, C Eisley, E Fritz-Waters, JM Reecy, JC Dekkers, RR Rowland, JK Lunney, CW Ernst, CK Tuggle. 2015. Whole blood microarray analysis of pigs showing extreme phenotypes after a porcine reproductive and respiratory syndrome virus infection. BMC Genomics. 16:516.


• Schweer WP, Schwartz K, Burrough E, Yoon KJ, Sparks C, Gibson KA, Gabler NK. 2015. The effect of PRRSV and PEDV challenge on growing pigs I: Growth Performance and digestibility. J Ani Sci doi:10.2527/jas2015-9834 (accepted).


• Schweer WP, Pearce SC, Burrough E, Schwartz K, Yoon KJ, Sparks C, Gabler NK^. The effect of PRRSV and PEDV challenge on growing pigs II: intestinal integrity and function. J Ani Sci doi:10.2527/jas2015-9836 (accepted).


• Sinha A, Gauger PC, Zhang J, Yoon KJ, Harmon KM. 2015. PCR-based retrospective evaluation of diagnostic samples for emergence of porcine deltacoronavirus in US swine. Vet Microbiol 179:296-298.


• Sinkora, M., Butler, J.E., Lager, K.M., Potockova, H., Sinkorova, J. 2014. The comparative profile of lymphoid cells and the T and B cell spectratype of germ-free piglets infected with viruses SIV, PRRSV or PCV2. Veterinary Research. 45:91.


• Spear, A., Faaberg, K.S. 2015. Development of a genome copy specific RT qPCR assay for divergent strains of type II porcine reproductive and respiratory syndrome virus. Journal of Virological Methods. 218:1-6.


• Ssemadaali , M.A Ilha , S. Ramamoorthy Genetic diversity of porcine circovirus type 2 and implications for detection and control.. Research in Veterinary Science. 103 (2015) 179–186.


• Stephenson, R, B Trible, Y Wang, M Kerrigan, S Goldstein, R Rowland. 2015. Multiplex serology for common viral infections in feral pigs in Hawaii between 2007 and 2010. Accepted for publication. J Wildlife Dis 51:239-2343.


• Stricker AM, Polson DD, Murtaugh MP, Christopher-Hennings J, Clement T. 2015. Variation in porcine reproductive and respiratory syndrome virus open reading frame 5 diagnostic sequencing. J Swine Health Prod. 23:18-27.


• Strizhakova O.M. Isolation and identification of epizootic diarrhea virus in pigs under outbreak at a large farm. Agrobiology, 2013; № 4, P. 65-69, doi: 10.15389/agrobiology.2013.4.65eng


• Subramaniam S, Piñeyro P, Tian D, Overend C, Yugo DM, Matzinger SR, Rogers AJ, Haac ME, Cao Q, Heffron CL, Catanzaro N, Kenney SP, Huang YW, Opriessnig T, Meng XJ. 2014. In vivo targeting of porcine reproductive and respiratory syndrome virus antigen through porcine DC-SIGN to dendritic cells elicits antigen-specific CD4T cell immunity in pigs. Vaccine 32:6768-6775.


• Thimmasandra Narayanappa A, Sooryanarain H, Deventhiran J, Cao D, Ammayappan Venkatachalam B, Kambiranda D, LeRoith T, Heffron CL, Lindstrom N, Hall K, Jobst P, Sexton C, Meng XJ, Elankumaran S. 2015. A novel pathogenic mammalian orthoreovirus from diarrheic pigs and swine blood meal in the United States. mBio 6(3):e00593-15. doi:10.1128/mBio.00593-15.


• Thomas JT, Chen Q, Gauger PC, Giménez-Lirola LG, Sinha A, Harmon KM, Madson DM, Burrough ER, Magstadt DR, Salzbrenner HM, Welch MW, Yoon KJ, Zimmerman JJ, Zhang J. 2015. Effect of porcine epidemic diarrhea virus infectious doses on infection outcomes in naïve conventional neonatal and weaned pigs. PLoS ONE 10(10): e0139266.


• Thomas M, Z. Wang, C.C. Sreenivasan, B.M. Hause, G.J. Renukaradhya, F. Li, D.H. Francis, R.S. Kaushik and M. Khatri (2015). Poly I:C adjuvanted inactivated swine influenza vaccine induces heterologous protective immunity in pigs. Vaccine, 33(4):542-548.


• Thomas PR, Karriker LA, Ramirez A, Zhang J, Ellingson JS, Crawford KK, Bates JL, Hammen KJ, Holtkamp DJ. 2015. Evaluation of time and temperature sufficient to inactivate porcine epidemic diarrhea virus in swine feces on metal surfaces. J Swine Health Prod 23:84-90.


• Tian D, and X.J. Meng. 2015. Amino acid residues Ala283 and His421 in the RNA-dependent RNA polymerase of porcine reproductive and respiratory syndrome virus play important roles in viral Ribavirin sensitivity and quasispecies diversity. Journal of General Virology. 2015 Oct 19. doi: 10.1099/jgv.0.000316.


• Tian D, Ni YY, Zhou L, Opriessnig T, Cao D, Piñeyro P, Yugo DM, Cao Q, Overend C, Heffron CL, Halbur PG, Pearce DS, Calvert JG, and Meng XJ. 2015. Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs. Virology. 485:402-413.


• Tian D, Ni YY, Zhou L, Opriessnig T, Cao D, Piñeyro P, Yugo DM, Overend C, Cao Q, Lynn Heffron C, Halbur PG, Pearce DS, Calvert JG, Meng XJ. 2015. Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs. Virology 485:402-413..


• Titov I., Tsybanov S., Malogolovkin A. Genotyping of classical swine fever virus using high-resolution melt analysis. J Virol Methods. 11/2015; Р. 224:53-7. doi: 10.1016/j.jviromet.2015.08.012.


• Trible, BR, LN Popescu, N Monday, J G Calvert, RRR Rowland. 2015. A single amino acid deletion in the matrix protein of porcine reproductive and respiratory syndrome virus confers resistance to a polyclonal swine antibody with broadly neutralizing activity. J Virol 89:6515-6520.


• Vannucci FA, Linhares DCL, Martheler D, Barcellos DE. 2015. Identification and complete genome of Seneca Valley virus in vesicular fluid and sera of pigs affected with idiopathic vesicular disease, Brazil. Transbound Emerg Dis (doi:10.1111/tbed.12410).


• Vannucci, FA, Linhares DC, Barcellos DE, Lam HC, Collins J, Marthaler D. (2015) Identification and Complete Genome of Seneca Valley Virus in Vesicular Fluid and Sera of Pigs Affected with Idiopathic Vesicular Disease, Brazil. Transbound Emerg Dis. 62:589-93.


• Vergne T, Gogin A, Pfeiffer D.U. Statistical Exploration of Local Transmission Routes for African Swine Fever in Pigs in the Russian Federation, 2007-2014. Transboundary and Emerging Diseases, 07/2015. doi: 10.1111/tbed.12391


• Vu HL, Ma F, Laegreid WW, Pattnaik AK, Steffen D, Doster AR, Osorio FA. (2015). A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection. J Virol. 2015 Dec 1;89(23):12070-83. PMID:26401031


• Waide, EH, JC Dekkers, JW Ross, RR Rowland, CR Wyatt, CL Ewen, AB Evans, DM Thekkoot, NJ Boddicker, NV Serão, NM Ellinwood, CK Tuggle. Not all SCID pigs are created equally: Two independent mutations in the artemis gene cause SCID in pigs. J Immunol. 195:3171-3179.


• Wang X, Marthaler D, Rovira A, Rossow S, Murtaugh MP. 2015. Emergence of a virulent porcine reproductive and respiratory syndrome virus in vaccinated herds in the United States. Virus Res. 210:34-41.


• Wang, X., H. Zhang, A. Able, E. Nelson. 2015. Protein Kinase R (PKR) Plays a Pro-viral Role in Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Replication by Modulating Viral Gene Transcription. Arch. Virol. 10.1007/s00705-015-2671-0.


• Warren KJ, Slattery M, Hallam J, Naik S, Thompson N, Cahill M, Wyatt T, Yoon KJ, Kohut M. 2015. Exercise improves host response to influenza viral infection in obese and non-obese C57/BL6 mice through different mechanisms. PLoS One 10(6): e0129713.


• Wei H, Lenz SD, Thompson DH, Pogranichniy RM. DNA-epitope vaccine provided efficient protection to mice against lethal dose of influenza A virus H1N1. Viral Immunol. 2014 Feb; 27(1): 14-19.


• Whitworth, KM, RRR Rowland, CL Ewen, BR Trible, MA Kerrigan, AG Cino-Ozuna, MS Samuel, D McLaren, A Mileham, KD Wells, RS Prather. CD163 facilitates both entry and replication of porcine reproductive and respiratory syndrome virus. Nature Biotech. In press.


• Xiao CT, Halbur PG, Opriessnig T. 2015. Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase in PCV2d. J Gen Virol doi:10.1099/vir.0.000100.


• Xiujin Wang, Lei Hou, Jige Du, Lei Zhou, Xinna Ge, Xin Guo, Hanchun Yang: Capsid, membrane and NS3 are the major viral proteins involved in autophagy induced by Japanese encephalitis virus. Veterinary Microbiology 05/2015; 178(3-4). DOI:10.1016/j.vetmic.2015.05.026


• Zhang J, Piñeyro P, Zheng Y, Li G, Rademacher C, Derscheid R, Guo B, Yoon KJ, Madson D, Gauger P, Schwartz K, Harmon K, Linhares DCL, Main R. 2015. Full-length genome sequences of Senecavirus A from recent idiopathic vesicular disease outbreaks in United States swine. Genome Announc 3(6):e01270-15.


• Zhang, Q., and Yoo, D. 2015. PRRS virus receptors and their role for pathogenesis. Vet Microbiol (Review) 177: 229-241.

 

• Abstracts or Proceedings

                   

• O'Donnell V, Holinka LG, Krug PW, Gladue DP, Carlson J, Sanford B, Alfano M, Kramer E, Lu Z, Arzt J, Reese B, Carrillo C, Risatti GR, Borca MV (2015). “African Swine Fever Virus Georgia 2007 with a deletion of virulence-associated gene 9GL (B119L), when administered at low doses, leads to virus attenuation in swine and induces an effective protection against homologous challenge”. J. Virol. 89(16) 8556-66.


• Magtoto R.L, Vegi A, Wang C, Johnson J. K and Ramamoorthy. S. A comparison of serological tests for Lawsonia intracellularis in swine. 2014 CRWAD Chicago, IL


• K and Ramamoorthy. S. Examining the cross-species infectivity of human and swine specific torque teno viruses (TTVs). 2014 CRWAD


• Molecular epidemiology supporting the surveillance and control of viral diseases in animal health in Cuba. Carmen L. Perera1, Ana María Acevedo1, Abdulahi Alfonso1, Nadia Martínez1, Liani Coronado1, Damaris Relova1, Yoandri Hinojosa1, Orlando Martínez2, Liliam Ríos1, María Irian Percedo1, Armando Vega1, Heidy Díaz de Arce1, María T. Frías1 and Lester J. Pérez1.   Poster, ISVEE 2015, Mérida


• Spatial analysis of Classical Swine Fever outbreaks in Pinar del Río province, Cuba


• Fonseca1,3*, K. R. Santoro2, P. Alfonso1, M. A. Abeledo1, O. Fernández1, M. Blanco4, Y. Rabelo4, M. I. Percedo1. Poster, ISVEE 2015, Mérida


• Peste porcina clásica: situación mundial y fuerzas que rigen su evolución en Cuba.


• Carmen L. Perera1, Lester J. Pérez1 , Liliam Ríos1, Damarys Relova1, Ana María Acevedo1, Liani Coronado1, María I. Percedo2, Osvaldo Fonseca2y María T. Frías1. Porcicultura Tropical 2015, Habana.


• Desarrollo de un ensayo isotérmico de detección del virus de la peste porcina clásica aplicable en laboratorios territoriales. Liani Coronado Báez, L. Perera1, Lester J. Pérez1 , Liliam Ríos1, Damarys Relova1, Ana María Acevedo1, Liani Coronado1, María I. Percedo2, Osvaldo Fonseca2y María T. Frías. Conference, Porcicultura Tropical 2015, Habana.


• La PCR: una realidad en el diagnóstico virológico en animales de interés económico en Cuba. Liani Coronado Baez, Conference, SISA 2015, Varadero


• A novel classical swine fever candidate vaccine: a subunit coupled antigen E2 and swine CD-154, an approach with live attenuated vaccine. María Pilar Rodríguez Moltó. Conference, SISA 2015, Varadero.


• A novel classical swine fever candidate vaccine: a subunit coupled antigen E2 and swine CD-154, pre-clinical efficacy studies. Marisela Suarez Pedroso; Maria Pilar Rodriguez Molto; Milagros Vargas Hernandez; Nemecio Gonzales Fernandez, Ileana Sosa Testé; Avelina León Goñi; Nelson Merino, Paula Naranjo Valdés; Yoandri Hinojosa López; Carmen L. Perera Gonzalez; Maria Teresa Frías Lepoureau; Mario Pablo Estrada. Poster, SISA 2015, Varadero.


• Caracterización molecular y filogenética de virus de influenza H1N1/2009 pandémica de cerdos en Cuba. Armando Vegaa, Liani Coronadoa, Carmen Laura Pereraa, María T. Fríasa, Dagmar Rouseauxb y Lester J. Péreza. Poster, SISA 2015, Varadero.


• CSF in Cuba, Advances research. Lester J. Pérez, Conference, ESVV 2015, Montpellier.


• Emergence of novel NADC30-like Strain of Porcine Reproductive and Respiratory Syndrome Virus in China. Lei Zhou*, Zichun Wang, Yuping Ding, Xinna Ge, Xin Guo, Hanchun Yang. International PRRS Symposium, 2014, Ghent, Belgium.


• The Role of Nonstructural Proteins in Virulence and Pathogenicity of PRRSV. Hanchun Yang. International PRRS Symposium, 2014, Ghent, Belgium.


• Abente EJ, Rajao DS, Kitikoon P, Anderson TK, Lager KM, Gauger PC, Vincent AL. November 2014. Pathogenesis and transmission studies: Non-swine influenza A viruses in the swine host. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 68-71.


• Abente, E.J., Lewis, N.S., Santos, J., Rajao, D., Perez, D., Vincent, A.L.. Substitutions near the receptor binding site can cause major antigenic changes in swine influenza. 3rd International Symposium on Neglected Viruses, Athens, Georgia.


• Abente, E.J., Lewis, N.S., Santos, J., Rajao, D., Perez, D., Vincent, A.L. 2015. Substitutions near the receptor binding site can cause major antigenic changes in swine influenza. Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting, Rochester, New York.


• Abente, E.J., Rajao, D.S., Kitikoon, P., Anderson, T.K., Lager, K.M., Gauger, P.C., Vincent, A.L. 2015. Pathogenesis and transmission studies: non-swine influenza A viruses in the swine host. Iowa State University Swine Disease Conference, Ames, Iowa.


• Alonso C, Raynor P, Morrison R, Davies P, Torremorell M (2015). Airborne transmission of PED virus and effect of the electrostatic particle ionization technology on decreasing airborne swine viruses. Proc Am Assoc Swine Veterinarians, Orlando, FL, p:59-61.


• Alvarez J., Valdes-Donoso P., Tousignant S., Morrison R., Perez A. Novel analytic tools for surveillance, diagnosis and control of PRRS in endemic settings. Invited keynote speaker at the 7th ISERPD. 2015, Kyoto, Japón


• Anderson, T.K., Stratton, J.A., Macken, C.A., Vincent, A.L. 2015. An automated tool for quantifying spatial and temporal dynamics of influenza A in North American swine. 3rd International Symposium on Neglected Viruses, Athens, Georgia.


• Azeem S, Ghorbani-Nezami S, Allam A, Cooper VL, Burrough E, Schwartz KJ, Plummer P, Arruda PH, Gauger PC, Kinyon JM, Madson D, Sahin O, Stevenson G, Yoon KJ. October 2015. A multiplex real-time PCR panel for detection of major bacterial and viral agents causing abortion in small ruminants. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 37.


• Bai J, Liu X, Ransburgh R, Fang Y, Anderson G. 2015. Co-detection of different genotypes of FMDv, ASFv and CSFv with a high-throughput MassTag System. Center of Excellence for Emerging and Zoonotic Animal Diseases Annual Meeting, Nebraska City, NE.


• Baldry H, Allerson, M, Diaz A, Yang M, Culhane M, Perez A, Torremorell M (2015). Impact of piglet weight and weaning age on influenza A virus infection and nucleoprotein antibody levels at weaning. Proc Am Assoc Swine Veterinarians, Orlando, FL, p: 83-87.


• Bhandari M, Madson M, Bower L, Hoang H, Sun D, Brodie J, Magstadt D, Arruda P, Burrough E, Wilberts B, Wang C, Yoon KJ. March 2015. Viremia and tissue distribution of porcine epidemic diarrhea virus in weaned pigs after experimental infection. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, p. 33-34.


• Binjawadagi, B, Z. Longchao, S. Dhakal, J. Hiremath, K. Ouyang, B. Shyu, J. J. Torrelles, D. Jackwood, Y. Fang, and G.J. Renukaradhya. Production and evaluation of porcine reproductive and respiratory syndrome virus like particles in pigs. Poster# 088, North American PRRS Symposium, December 5-6, 2014, Chicago, IL.


• Bjustrom-Kraft J, Woodard K, Giménez-Lirola L, Rotolo M, Wang C, Lasley P, Chen Q, Zhang J, Baum D, Gauger P, Yoon KJ, Zimmerman J, Main R. November 2015. Understanding PEDV shedding and antibody kinetics will aid in implementing effective gilt acclimatization procedures. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 34-35.


• Brito B, Dee S, Wayne S, Murtaugh M, Perez A. 2015. Novel molecular epidemiology tools to assess the relation among porcine reproductive and respiratory syndrome viruses causing outbreaks in sow farms. Proc Amer Assoc Swine Veterinarians. 46:357-358.


• Burrough E, Schweer W, Schwartz K, Yoon KJ, Gabler N. June 2015. Impact of dual infection with PRRSV and PEDV on intestinal lesion severity and detection of PEDV nucleic acid. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 147.


• Burrough E. 2015. Emergence of porcine enteric coronaviruses in North America: Differential features and diagnostic trends. Emerging Disease Focus Seminar, Combined Annual Meeting of the American College of Veterinary Pathologists, American Society for Veterinary Clinical Pathology, and Society of Toxicologic Pathology. Minneapolis, Minnesota.


• Carrillo C, J Olivas, P Naraghi-Arani, S Gardner, J Bai, Y Fang, RRR Rowland, C Jaing. 2015. Simultaneous Detection of Ten Swine Respiratory Pathogens Using a Multiplexed Detection Assay. NA PRRS Symposium, Chicago, IL.


• Chen Q, Gauger P, Stafne M, Thomas J, Arruda P, Burrough E, Madson D, Brodie J, Magstadt D, Derscheid R, Welch M, Zhang J. June 2015. Pathogenicity and pathogenesis of a U.S. Porcine Deltacoronavirus cell culture isolate in 5-day-old naïve neonatal piglets. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 160.


• Chen Q, Gauger PC, Stafne MR, Thomas JT, Arruda PH, Burrough ER, Madson DM, Brodie J, Magstadt DR, Derscheid RJ, Welch MW, Zhang J. October 2015. Development of porcine deltacoronavirus (PDCoV) diagnostic tools and investigation of pathogenesis of a US PDCoV cell culture isolate in 5-day-old piglets. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 155.


• Chen Q, Thomas J, Hunter F, Gauger PC, Harmon KM, Main RG, Zhang J. October 2015. Evaluation of commercial rapid PED, TGE, and Rota ag test kits for detecting virus pathogens in porcine feces. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 193.


• Chen Q, Thomas JT, Giménez-Lirola LG, Gauger PC, Hardham JM, Rapp-Gabrielson VJ, Madson D, Magstadt DR, Welch MW, Salzbrenner H, Zhang J. March 2015. In vitro evaluation of serological cross-reactivity and cross-neutralization between the U.S. PEDV original and variant strains. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 53-54.


• Chen Z, F Yuan, Y Wang, P Shang, B M Hause, Y Fang. 2015. Production and characterization of monoclonal antibodies against emerging swine pestivirus. NA PRRS Symposium, Chicago, IL.


• Chen Z, F Yuan, Y Wang, P Shang, B M Hause, Y Fang. 2015. Production and characterization of monoclonal antibodies against emerging swine pestivirus. Conference of Research Workers in Animal Diseases, Chicago, IL.


• Chen, W-Y., Calzada-Nova, G., Schnitzlein, W., Zuckermann, F.A.. 2014. The PRRSV-mediated inhibition of IFN production by pig alveolar macrophages occurs at the post-transcriptional level via the activation of eIF-2. Pathobiology Department, University of Illinois at Urbana-Champaign, IL CRWAD, Chicago, IL, December 2014.


• Clifton AS, Schweer WP, Pearce SC, McKilligan DM, Schwartz K, Yoon KJ, Gabler NK. March 2015. Water administration of glucose and amino acids attenuates changes in intestinal structure and lesion scores in PRRSV and PEDV co-infected pigs. Midwest American Society of Animal Science. Des Moines, Iowa, Abstr#406.


• Cline G, Wetzell T, Sievers C, Madson D, Zimmerman J, Giménez-Lirola L, Leuwerke B. June 2015. A comparison of the porcine epidemic diarrhea virus serum IgG and milk IgA prevalence in a group of sows 12 weeks after natural exposure. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 149.


• Crawford, K., Lager, K.M., Miller, L.C., Loving, C.L., Opriessnig, T., Gerber, P. 2014. Evaluation of porcine epidemic diarrhea virus transmission and the immune response in growing pigs. Conference of Research Workers in Animal Diseases, December 7-9, 2014, Chicago, Illinois.


• Curry SM, Gibson KA, Burrough ER, Schwartz KJ, Yoon KJ, Gabler NK. September 2015. Comparison of PEDV, PDCoV and TGEV infection on performance and protein accretion of pigs. Proc Allen D. Leman Swine Conference. St. Paul, Minnesota, p. 49.


• Davies B, Tseng A, Wagner M, Martins K, Stone S, Dvorak C, Laube K, Davies R, Murtaugh M. 2015. Improving data integrity and reliability in animal science research. Soc Quality Assurance 31st Annual Meeting, Tampa FL. 12-17 April.


• Davies RL, Laube K, Wees C, Davies BR, Tseng A, Wagner M, Martins K, Stone S, Dvorak C, Murtaugh M. 2015. Improving data integrity and reliability in the research phase of diagnostic test development. Amer Assoc Vet Lab Diagn. Providence RI. Oct 22-28.


• Dee, S., C. Neill, T. Clement, J. Christopher-Hennings, E. Nelson. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feed. 2014 NA PRRS Symp. p.117.


• Dee, S., T. Clement, A. Schelkopf, J. Nerem, D. Knudsen, J. Christopher-Hennings, E. Nelson. An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: Proof of concept. 2014 NA PRRS Symp. p.116.


• Dee, S., T. Clement, A. Singrey, J. Christopher-Hennings, E. Nelson. An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of viral proxies for foreign animal diseases in contaminated feed. 2014. NA PRRS Symp. p.118.


• Dee, S., T. Clement, J. Christopher-Hennings, E. Nelson. Assessing the viability of porcine epidemic diarrhea virus in dry feed at 4 degrees C. 2014 NA PRRS Symp. p.119.


• Dhakal, S., J. Hiremath, J. Goodman, Y. S. Lakshmanappa, B. Shyu, K. Oyuang, B. Narasimhan, G.J. Renukaradhya (2015). Nanoparticle based vaccine strategy against swine influenza virus. Nanovaccine Research Initiative, Iowa State University, Ames, Iowa. May 26 – 28, 2015.


• Diaz A, Corzo C, Culhane M, Sreevatsan S, Torremorell M (2015). Co-circulation of influenza A viruses in swine populations. Minnesota Veterinary Medical Association Conference, Minneapolis.


• Diaz A, Culhane M, Sreevatsan S, Torremorell M (2015). Dynamics of co-circulating H1N1 and H3N2 influenza A virus in a cohort of pigs after weaning. Proc Am Assoc Swine Veterinarians. Orlando, FL, p:73.


• Drebes D, Nelson E, Murtaugh M, King D, Connor J. 2015. The effect of translactational antibodies on preweaning mortality in a porcine epidemic diarrhea virus exposed herd. Proc Amer Assoc Swine Veterinarians. 46:283-284.


• Drebes, D., L. Greiner, E. Nelson, M. Murtaugh, D. King, and J. Connor. The effect of translactational antibodies on preweaning mortality in a porcine epidemic diarrhea virus exposed herd. 2015 AASV.


• Emily Morse, Junru Cui, Antonio Garmendia (2015). Induction of Interferon Responses in Swine Macrophages using Nucleic Acid-Free PRRSV Envelope Protein Extracts.   Frontiers in Undergraduate Research, UConn, Storrs April 11th, 2015


• Faaberg, K.S., Kappes, M.A. and Miller, C.L. 2015. Porcine reproductive and respiratory syndrome virus nonstructural protein 2 membrane topology. International PRRS Congress, Ghent, Belgium.


• Faaberg, K.S., Kappes, M.A. and Miller, C.L. 2015. Porcine reproductive and respiratory syndrome virus nonstructural protein 2 membrane topology. W45-12. 34th Annual Meeting of the American Society for Virology, London, Ontario, Canada.


• Fang Y, Snijder, EJ. 2015. The molecular biology of PRRSV: replication charateristics and interplay with host cell infrastructure. International PRRS Congress, Ghent, Belgium.


• Ganwu Li. October 2015. Whole genome sequencing of viral pathogens from clinical samples using next-generation sequencing technology. Virology Symposium, Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island.


• Gauger PC, Dias AS, Vincent AL, Stratton J, Kitikoon P, Baker RB, Zhang J. April 2015. Detection and characterization of endemic influenza A virus in neonate and nursery pigs in a farm using inactivated influenza sow vaccines. Proc 3rd International Symposium on Neglected Influenza Viruses. Athens, Georgia, p. 10.


• Gauger PC, Rajao DS, Anderson TK, Abente EJ, Zhang J, Vincent AL. October 2015. Novel human-like swine H3N1 and H3N2 influenza A viruses detected in pigs. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 147.


• Gauger PC, Vincent AL, Harmon KC, Zhang J. March 2015. Influenza A viruses in swine: diversity, diagnostics and interpretation. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, p. 493-501.


• Gauger, P.C., Dias, A., Vincent, A.L., Baker, R.B., Zhang, J., Kitikoon, P. 2015. Detection and characterization of influenza A virus endemic circulation in neonatal and nursery pigs in a farm using an inactivated influenza vaccine. 3rd Neglected Influenza Symposium, Athens, Georgia


• Gauger, P.C., Vincent, A.L., Harmon, K.M., Zhang, J. 2015. Influenza A viruses in swine: diversity, diagnostics and interpretation. American Association of Swine Veterinarians 46th Annual Meeting, February 28 - March 3, 2015, Orlando, Florida.


• Giménez-Lirola L, Baum D, Bower L, Chen Q, Sun D, Johnson JK, Madson D, Magtoto R, Poonsuk K, Sarmento L, Yoon KJ, Zhang JQ, Zimmerman JJ, Main R. February 2015. Serology: Overview of PED antibody response. 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida. Seminar #2, pp. 7-9.


• Giménez-Lirola L, Poonsuk K, Zhang J, Arruda P, Chen Q, Correa da Silva Carrion L, Magtoto R, Piñeyro P, Sarmento L, Madson D, Johnson J, Wang C, Yoon KJ, Zimmerman J, Main R. November 2015. Effects of PEDV passive antibody on disease and the neonatal immune response. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 50-51.


• Giménez-Lirola LG, Gonzalez W, Rotolo M, Poonsuk K, Wang C, Zimmerman J. April 2015. Developments in oral fluid-based diagnostic technology. Proc 14th Chulalongkorn University Veterinary Conference. Bangkok, Thailand, p. 97.


• Giménez-Lirola LG, Mur L, Rivera B, Wang C, Goodell C, Rowland RB, Harris DL, Gallardo C, Arias M, Sánchez-Vizcaíno J, Zimmerman JJ. December 2014. African swine fever virus (ASFV) rp30 ELISA detects antibody in serum and/or oral fluid specimens. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #172.


• Giménez-Lirola LG, Mur L, Rivera B, Wang C, Lizano S, Goodell C, Rowland R, Harris DL, Gallardo C, Arias M, Sánchez-Vizcaíno JM, Zimmerman J. June 2015. Development of a dual-matrix serum/oral fluid ASFV p30 antibody ELISA test. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 98.


• Giménez-Lirola LG, Rotolo M, Poonsuk K, Gonzalez W, Wang C, Zimmerman J. April 2015. Applications of oral fluid testing in the field. Proc 14th Chulalongkorn University Veterinary Conference. Bangkok, Thailand, p. 99.


• Giménez-Lirola LG, Zhang J, Poonsuk K, Rotolo M, Zimmerman J. April 2015. Porcine epidemic diarrhea virus in the U.S. – Response and future challenges. Proc 14th Chulalongkorn University Veterinary Conference. Bangkok, Thailand, p. 95.


• Goede D, Dvorak C, Murtaugh M, Nere J, Yeske P, Rossow K, Morrison RB. 2015. Previous infection of sows with a “mild” strain of PED virus confers protection against infection with a “severe” strain. Proc Amer Assoc Swine Veterinarians. 46:55-57.


• Gonzalez W, Giménez-Lirola LG, Gottschalk M, Wang C, Holmes A, Lizano S, Goodell C, Poonsuk K, Sitthichaoenchai P, Zimmerman J. June 2015. Actinobacillus pleuropneumoniae (APP) ApxIV toxin antibody ontogeny in serum, oral fluid and fecal specimens from animals inoculated under experimental conditions. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 79.


• Gonzalez W, Giménez-Lirola LG, Gottschalk M, Wang C, Holmes A, Lizano S, Goodell C, Poonsuk K, Sitthichaoenchai P, Zimmerman J. December 2014. Actinobacillus pleuropneumoniae (APP) ApxIV toxin antibody ontogeny in serum, oral fluid, and fecal specimens from animals inoculated under experimental conditions. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #19.


• Guo R, B B Katz, J Tomich, Y Fang. 2015. Porcine reproductive and respiratory syndrome virus hijacks nanotubes for intercellular spread: an alternative pathway used for nidovirus transmission. NA PRRS Symposium, Chicago, IL.


• Guo R, B B Katz, J Tomich, Y Fang. 2015. Porcine reproductive and respiratory syndrome virus hijacks nanotubes for intercellular spread: an alternative pathway used for nidovirus transmission. Conference of Research Workers in Animal Diseases, Chicago, IL.


• Gutierrez, A.H., Loving, C.L., Moise, L., Martin, W., De Groot, A.S. 2014. Universal influenza vaccine development for swine using novel immunoinformatic tools. Conference of Research Workers in Animal Diseases, Chicago, Illinois.


• Gutierrez, A.H., Loving, C.L., Moise, L., Martin, W., De Groot, A.S. 2014. Predicting vaccine efficacy for food animals using the epitope content comparison (EpiCC) tool: application to PRRSv. Conference of Research Workers in Animal Diseases, Chicago, Illinois.


• Han M., and Yoo, D. 2014. IFN phenotype mutant PRRS viruses with a modified regulatory role of SAP-like motif in nsp1-beta. 2014 North American PRRS Symposium. Chicago, IL Dec 5-6.


• Han M., and Yoo, D. 2014. Regulatory role of the SAP-like motif of PRRSV nsp1-beta protein for innate immune response. 95th CRWAD Chicago, IL Dec 7-9.


• Han, M., and Yoo, D. 2014. Regulatory role of the SAP-like motif of PRRSV nsp1β protein for innate immune response. 95th CRWAD, Chicago, IL Dec 7-9.


• Hiremath, J, M. Elaish, K. Kyung-il, B. Binjawadagi, K. Ouyang, S. Dhakal, C.W. Lee, and G.J. Renukaradhya. PLGA-Nanoparticle entrapped swine influenza virus peptides vaccine induces epitope specific cell-mediated immune response in pigs. Abstract #103, 95^th Annual CWRAD meeting, December 7-9, 2014, Chicago, IL.


• Holmes A, Abate S, Gauger P, Gonzalez W, Yoon K, Wang C, Zimmerman J. December 2014. Effect of pretreatment on detection of PRRSV in oral fluid by qRT-PCR. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #137.


• Holmes A, Kittawornrat A, Goodell C, Panyasing Y, Hoff S, Subramanya K, Wang C, Zimmerman JJ. December 2014. Behavioral aspects of oral fluid sample collection. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #71.


• Hughes HR, Olson ZF, Gauger PC, Vincent AL, Brockmeier SL, Loving CL. Immune mechanisms associated with enhanced influenza A virus disease versus cross-protection in vaccinated pigs. May 2015. Proc American Association of Immunologists Annual Meeting. New Orleans, Louisiana, 194:72.15.


• Hughes, H.R., Brockmeier, S., Loving, C.L. 2015. Live-attenuated influenza virus vaccine protects pigs from transmission of heterologous H1 influenza A virus. Vaccines Against Antigenically Variable Viruses, Ames, Iowa.


• Hughes, H.R., Olson, Z.F., Gauger, P.C., Vincent, A.L., Brockmeier, S., Loving, C.L. 2014. Lymphocyte responses in the lungs of vaccinated pigs following homologous and heterologous influenza A virus challenge. Autumn Immunology Conference, Chicago, Illinois.


• Hughes, H.R., Vincent, A.L., Brockmeier, S., Perez, D., Loving, C.L. 2014. Mucosal correlates of cross-protection for live-attenuated influenza virus vaccines in pigs. Conference of Research Workers in Animal Diseases, Chicago, Illinois.


• Iglesias I., Montes F., Muñoz MªJesús, Arias M., Gogin A., Kolbasov D., de la Torre A. Role of wild boars and domestic pigs in the spread of African swine fever in the Russian Federation (2007-2013) – Abstracts and poster 8 th Annual EPIZONE Meeting «Primed for tomorrow» 23-25 September 2014 in Copenhagen. – Denmark.


• Iglesias I., Muñoz MªJesús,, Arias M., Montes F., Pérez A., Gogin A., Kolbasov D., de la Torre A. Identification of the Reproductive ratio for the local spread of African swine fever in wild boars in the Russian Federation. - Abstracts and poster 8 th Annual EPIZONE Meeting «Primed for tomorrow» 23-25 September 2014 in Copenhagen. – Denmark.


• Cui*, C. M. O’Connell, J. D. Smith, J. Smyth, P. H. Verardi, and A. E. Garmendia. (2014). Responses of Swine to Mosaic DNA Vaccines for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). 2014 North American PRRS Symposium, December 5-6, 2014, Chicago, Illinois.


• Cui, C. M. O’Connell, J. D. Smith, J. Smyth, A. Costa, P. H. Verardi, Y. Pan, D.J. Burgess and A. E. Garmendia (2015). Immunogenicity of Mosaic ORF5 DNA Vaccines against Porcine Reproductive and Respiratory Syndrome (PRRS) in Swine. Ninth Annual Vaccine Renaissance Conference, November 4-6, 2015, Providence, Rhode Island.


• Cui, C. O’Connell, J. Smyth, P. Verardi, and A. Garmendia (2015). Mosaic T cell Epitope Vaccines for PRRSV Induce Cell-mediated Immune Responses While Retaining the Ability to Induce Neutralizing Antibodies in Swine. Graduate Student Research Forum CAHNR, UCONN March 2015


• Jolene Carlson1,2*, Brenton Sanford1, Erin Howey1, Peter Krug1, Marialexia Alfano1, Vivian O’ Donnell1,3, Lauren Holinka1, Doug Gladue1, Jonathan Arzt1, Guillermo Risatti3, Stephen Higgs2, Manuel Borca1 (2015). 1Plum Island Animal Disease Center, ARS, USDA, Greenport, NY 11944, USA, 2Department of Diagnostic Medicine & Pathobiology, Kansas State University, Manhattan, KS 66502, USA, 3Department of Pathobiology and Veterinary Science, CAHNR, University of Connecticut, Storrs, Connecticut, USA. Differences in pathogenesis and immuneresponses between attenuated and virulent African swine fever virus strains. 2015 NA PRRS Symposium.


• Kalpanie Bandara, Kara Rogers, Milton Levin, Sylvain De Guise and Guillermo Risatti (2015). A potential role for PRRSV non-structural protein 3 (NSP3) in modulation of apoptosis during infection. Graduate Student Research Forum, CAHNR, UCONN, April 2015, Storrs, CT.


• Kalpanie Bandara1, Kara Rogers1, Milton Levin1, Sylvain De Guise1, Douglas P. Gladue2, Lauren G. Holinka2, Manuel V. Borca2, and Guillermo Risatti1 (2014). A potential role for PRRSV non-structural protein 3 (NSP3) in modulation of apoptosis in MARC 145 cells. 1Department of Pathobiology and Veterinary Science, College of Agriculture, Health and Natural Resources, University of Connecticut, Storrs, CT. 2USDA, ARS, Plum Island Animal Disease Center, Orient Point, NY. 2014 North American PRRS Symposium, Dec.2014, Chicago, IL.


• Katorkin S.,Gazaev I, Titov., Malogolovkin A., Tsybanov S., Kolbasov D.   Detection of genetic heterogeneity in African swine fever virus populations in Russia. Abstracts and poster 8 th Annual EPIZONE Meeting «Primed for tomorrow» 23-25 September 2014 in Copenhagen. – Denmark.


• Kinsley, A. VanderWaal, K., Patterson, G., Evanson, J., Sampedro, F., Craft, M., Perez, A. (2015). Development of parameter values for a within- and between-herd transmission model for foot and mouth disease in swine. Invited poster at: Center of Excellence for Emerging and Zoonotic Animal Diseases Annual Meeting. Nebraska City, NE.


• Lawson, S., F. Okda, X. Liu, A. Singrey, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of an indirect ELISA, a fluorescent microsphere immunoassay (FMIA) and a blocking ELISA for detection of antibodies against porcine epidemic diarrhea virus (PEDV). 2014 NA PRRS Symp. p.48.


• Lee, C-W, K. Kang, M. Elaish, J.M. Ngunjiri, H. Jang, A. Ali, J. Hiremath, S. Dhakal, Xia, X. Jiang, and G.J. Renukaradhya. Efficacy of M2e-based vaccine in Murine, Avian and Swine Models. Abstract #175, 95^th Annual CWRAD meeting, December 7-9, 2014, Chicago, IL.


• Li Y, Shyu D, Shang PC, Bai J, Ouyan K, Hireamt J, Binjawadagi B, Renukaradhya G, Fang Y. 2015. Mutations in the highly conserved GKYLQRRLQ motif of nsp1β protein impairs the innate immune suppression function of porcine reproductive and respiratory syndrome virus (PRRSV). International PRRS Congress, Ghent, Belgium.


• Li Y, Shyu D, Shang PC, Bai J, Ouyan K, Hireamt J, Binjawadagi B, Renukaradhya G, Fang Y. 2015. Mutations in the highly conserved GKYLQRRLQ motif of nsp1β protein impairs the innate immune suppression function of porcine reproductive and respiratory syndrome virus (PRRSV). NA PRRS Symposium, Chicago, IL.


• Li Y, Shyu D, Shang PC, Bai J, Ouyan K, Hireamt J, Binjawadagi B, Renukaradhya G, Fang Y. 2015. Mutations in the highly conserved GKYLQRRLQ motif of nsp1β protein impairs the innate immune suppression function of porcine reproductive and respiratory syndrome virus (PRRSV). Conference of Research Workers in Animal Diseases, Chicago, IL.


• Li Y, Tas A, Sun Z, Snijder EJ, Fang Y. 2015. Proteolytic Processing of Porcine Reproductive and Respiratory Syndrome Virus Replicase ORF1a Polyprotein. 26th Intercampus Virology Meeting, Nebraska City, NE.


• Li Y, Tas A, Sun Z, Snijder EJ, Fang Y. 2015. Proteolytic Processing of Porcine Reproductive and Respiratory Syndrome Virus Replicase ORF1a Polyprotein. NA PRRS Symposium, Chicago, IL.


• Linhares D, Vannucci FA. (2015). What the experts say: Epidemic transient neonatal losses and Senecavirus A. 12-Oct-2015. (<https://www.pig333.com/what_the_experts_say/epidemic-transient-neonatal-losses-and-senecavirus-a_10634/>).


• Linhares D. November 2015. Epidemic transient neonatal losses in Brazil and Senecavirus A. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 75-78.


• Linhares D.C., Holtkamp D.J. November 2015. PRRSV: Challenges and opportunities for controlling infection in breeding herds. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 13-18.


• Magstadt D, Gauger P, Madson D, Burrough E, Arruda P, Harmon K, Pillatzki A, Chen Q, Thomas J, Zhang JQ. March 2015. Cross-protection after challenge with a contemporary, heterologous PRRS virus in pigs vaccinated with Fostera™ PRRSV. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 363-364.


• Main R, Baum D, Chen Q, Gauger P, Giménez-Lirola L, Harmon K, Hong H, Li G, Madson D, Mueller K, Rademacher C, Stevenson G, Sun D, Woddrd K, Yoon K.J., Zhang J, Zimmerman J. June 2015. Emergence of PEDV in the United States: Events, observations, actions and lessons being learned. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 12.


• Miller L. C., Jiang, Z., Sang, Y., Harhay, G. P., and Lager, K. M. (2015). Evolutionary characterization of pig interferon-inducible transmembrane gene family and member expression dynamics in tracheobronchial lymph nodes of pigs infected with swine respiratory disease viruses [abstract]. Keystone Symposia on Molecular and Cellular Biology: Immunity to Veterinary Pathogens: Informing Vaccine Development (A3), Jan 20-25, 2015, Keystone, CO.


• Miller, L.C., Crawford, K., and Lager, K.M. (2014). Performance assessment of a real-time polymerase chain reaction assay for porcine epidemic diarrhea virus to assess PEDV transmission in growing pigs [abstract]. North American PRRS Symposium 2014, December 5-6 2014, Chicago, IL.


• Miller, L.C., Sang, Y., and Blecha, F. (2015). Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived dendritic cells at differential activation statuses [abstract]. 6th International Symposium on Animal Functional Genomics (ISAFG 2015), Università Cattolica del Sacro Cuore in Piacenza, Italy.


• Mirajkar NS, Murtaugh MP, Errecaborde KM, Hueston W. 2015. The impact of timely state appropriations for Minnesota’s response to porcine epidemic diarrhea. Issue brief, Food Policy Research Center, Univ Minnesota. http://www.foodpolicy.umn.edu/policy-summaries-and-analyses/impact-timely-state-appropriations-minnesota%E2%80%99s-response-porcine


• Murtaugh MP, Dvorak CMT. 2015. Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Prevalence of PCV2. Swinecast http://www.swinecast.com/dr-michael-murtaugh-and-dr-cheryl-dvorak-natural-infection-immunity-prevalence-pcv2


• Nino Vepkhvadze1, Maka Kokhreidze1, Ketevan Goginashvili1, Tamar Tigilauri1, Eliso Mamisashvili1, Lamara Gelashvili1, Thea Abramishvili1, Marina Donduasvili1, Otar Parkadze2, Lena Ninidze2, Natia Kartskhia2, Richard Weller3, and Guillermo R. Risatti4 (2015). 1Laboratory of the Ministry of Agriculture (LMA), Tbilisi, Republic of Georgia. 2National Food Agency (NFA), Tbilisi, Republic of Georgia. 3Fundamental Computational and Sciences Division, Pacific Northwest National Laboratory, USA. 4Department of Pathobiology and Veterinary Science, CAHNR, University of Connecticut, USA. Active Surveillance of African swine fever in commercial swine herds in the Republic of Georgia in 2014. CRWAD Meeting 2015, Chicago, IL.


• O'Donnell, V., Holinka, L.G., Gladue, D.P., Sanford, B., Krug, P.W., Lu, X., Arzt, J., Reese, B., Carrillo, C., Risatti, G.R., Borca, M.V. (2015). “African swine fever virus Georgia isolate harboring deletions of MGF360 and MGF505 genes is attenuated in swine and confers protection against challenge with the virulent parental virus”. J. Virol. doi:10.1128/JVI.00554-15


• Okda, F., S. Lawson, A. Singrey, X. Liu, J. Nelson, J. Christopher-Hennings, E.A. Nelson. Development of serological assays for detection of antibodies against porcine deltacoronavirus (PDCoV). 2014 NA PRRS Symp. p.51.


• Olsen CW, Zimmerman JJ, Angulo J. March 2015. The challenge of type 1 PRRSV isolation and propagation: A review. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, p. 335.


• Olson, Z.F., Sandbulte, M.R., Kunzler Souza, C., Perez, D.R., Vincent, A.L., Loving, C.L. 2014. Differential measures of antigen-specific immunogenicity in swine following influenza vaccination. Autumn Immunology Conference, Chicago, Illinois.


• Opriessnig T, Gerber P, Xiao C, Halbur P. March 2015. A commercial PCV2a vaccine and an experimental PCV2b vaccine both protect against challenge with a 2013 variant mPCV2b. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 65-66.


• Opriessnig T, Giménez-Lirola LG, Halbur P. March 2015. Luminex® application for PCV2 serological diagnosis. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, p. 417.


• Opriessnig T, Xiao CT, Gerber PG, Chen Q, Zhang J, Halbur PG. December 2014. Evidence from bioassays that commercial spray drying processes are effective at inactivating porcine epidemic diarrhea virus. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #61


• Ouyang, K, Hiremath, B. Binjawadagi, and G.J. Renukaradhya. Comparative analysis of routes of immunization of a live PRRS virus vaccine in a heterologous virus challenge study. Poster#100, North American PRRS Symposium, Dec 5-6, 2014, Chicago, IL.


• Ouyang, K, Hiremath, B. Binjawadagi, and G.J. Renukaradhya. Comparative analysis of routes of immunization of a live PRRS virus vaccine in a heterologous virus challenge study. Poster #069P, 95^th Annual CWRAD meeting, December 7-9, 2014, Chicago, IL.


• W. Krug, L.G. Holinka, V. O'Donnell, B. Reese, B. Sanford, I. Fernandez-Sainz, D.P. Gladue, J. Arzt, L. Rodriguez, G.R. Risatti and M.V. Borca. (2015). “The progressive adaptation of a Georgian isolate of African Swine Fever virus to vero cells leads to a gradual attenuation of virulence in Swine corresponding to major modifications of the viral genome”. J. Virol 89, 2324-2332.


• Perez A, Alkhamis M, Murtaugh M, Morrison B. 2015. PRRS virus changes like a flowing river. National Hog Farmer, 31 Aug 2015. http://nationalhogfarmer.com/animal-well-being/prrs-virus-changes-flowing-river


• Perez A., Alvarez J., Al-Ghalith G., Goede D., Morrison R. Spatial epidemiology of porcine epidemic diarrhea in the US. 14th ISVEE, Merida, Mexico


• Piñeyro PE, Rademacher C, Derscheid R, Guo B, Yoon K-J, Zhang J, Harmon K, Magstadt D, Gauger P, Chen Q, Arruda P, Stevenson G, Burrough E, Schwartz K, Cooper VL, Arruda BL, Baum D, Zimmerman J, Gimenez-Lirola LG, Correia-Lima-Linhares D, Halbur PG, Main R, Madson D. October 2015. Senecavirus A vesicular disease outbreak in Midwest show and commercial pigs. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 60.


• Pogranichniy RM, Porcine Epidemic Diarrhea virus (PEDv) Conference, Danville, IN. Testing and sampling at ADDL, Why these viruses are challenging for swine industry? 2014.


• Pogranichniy RM, Purdue University, Fall conference, Emerging, re-emerging and high impact diseases in swine and cattle, 2014.


• Poonsuk K, Giménez-Lirola L, Gonzalez W, Zhang J, Chen Q, Correa da Silva Carrion L, Olsen C, Magtoto R, Johnson J, Wang C, Madson D, Main R, Zimmerman J, Yoon KJ. March 2015. Defining PEDV maternal immunity and correlates of neonatal protection. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, p. 47.


• Poonsuk K, Giménez-Lirola LG, Gonzalez W, Zhang J, Chen Q, da Silva Carrion LC, Olsen C, Magtoto R, Johnson J, Wang C, Madson D, Main R, Zimmerman J, Yoon KJ. June 2015. Maternal humoral immunity and neonatal protection against PEDV infection. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 44.


• Poonsuk K, Giménez-Lirola, Gonzalez W, Zhang J, Chen Q, Carrion L, Olsen C, Magtoto R, Johnson J, Wang C, Madson D, Main R, Zimmerman J, Yoon KJ. December 2014. Relationship between maternal immune status and neonatal protection against PEDV infection. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #97.


• Rajao DS, Gauger PC, Anderson TK, Lewis NS, Abente EJ, Killian ML, Perez DR, Sutton TC, Zhang J, Vincent AL. July 2015. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from endemic viruses. Proc 8th Annual Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting. Rochester, New York, poster 54.


• Rajao DS, Gauger PC, Anderson TK, Lewis NS, Abente EJ, Killian ML, Zhang J, Vincent AL. April 2015. Novel human-like swine H3N2 and H3N1 influenza A viruses detected in pigs are virulent and distinct. Proc 3rd International Symposium on Neglected Influenza Viruses. Athens, Georgia, p. 9.


• Rajao, D.S., Gauger, P.C., Anderson, T.K., Lewis, N.S., Abente, E.J., Killian, M., Zhang, J., Vincent, A.L. 2-15. Novel human-like H3N2 and H3N1 influenza A viruses are virulent and transmissible in pigs and antigenically distinct from contemporary swine and human H3 strains. 3rd Neglected Influenza Symposium, Athens, Georgia


• Rajão, D.S., Gauger, P.C., Anderson, T.K., Lewis, N.S., Abente, E.J., Killian, M., Perez, D.R., Sutton, T.C., Zhang, J., Vincent, A.L. 2015. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from endemic viruses. Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting, Rochester, New York.


• Renukaradhya, G.J, Hiremath, J, M. Elaish, K. Kyung-il, B. Binjawadagi, K. Ouyang, S. Dhakal, and C.W. Lee. Nanoparticle entrapped swine influenza virus peptides vaccine induces epitope specific T cell response in pigs. Keystone Symposia: Immunity to Veterinary Pathogens: Informing Vaccine Development, Keystone Resort, Colorado, January 20—25, 2015.


• Renukaradhya, G.J, Hiremath, J, M. Elaish, K. Kyung-il, B. Binjawadagi, K. Ouyang, S. Dhakal, and C.W. Lee. Nanoparticle entrapped swine influenza virus peptides vaccine induces epitope specific T cell response in pigs. European Veterinary Immunology Workshop, Vienna, Austria, September 2 – 4, 2015. Torre D., Iglesias I., Bosch J., Gogin A., Kolbasov D., Munoz M. African Swine Fever wild life interactions in the Russian Federatin // Workshop on Laboratory Diagnosis of African and Classical Swine Fever (ASF and CSF)/ CISA-INIA.- Madrid, 2014.- P. 23.


• Roady, P.J., Calzada-Nova, G., Chen, W-Y., Zuckermann, F.A. 2014. Objective Assessment of the Extent of Lung Lesions in Pigs Infected with Porcine Reproductive and Respiratory Syndrome Virus, a Novel Approach. Veterinary Diagnostic Laboratory and Dept. of Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, IL. North American PRRS Symposium. Chicago, IL, Dec 7-8.


• Rotolo M, Giménez-Lirola L, Abate S, Hoogland M, Wang C, Baum D, Gauger P, Harmon K, Main R, Ramirez A, Zimmerman J. February 2015. Use of oral fluids in PEDV surveillance. 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida. Seminar #2, pp. 15-20.


• Rotolo M, Giménez-Lirola L, Sun Y, Abate S, Wang C, Baum D, Gauger P, Hoogland M, Main R, Zimmerman J. November 2015. Developing sampling guidelines for oral fluid-based PRRSV surveillance. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 90-91.


• Rotolo M, Giménez-Lirola LG, Abate S, Hoogland M, Wang C, Baum D, Gauger P, Harmon K, Main R, Ramirez A, Zimmerman J. October 2015. Developing sampling guideines for PEDV surveillance. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 60.


• Rotolo M, Giménez-Lirola LG, Abate S, Hoogland M, Wang C, Baum D, Gauger P, Harmon K, Main R, Ramirez A, Zimmerman J. June 2015. Use of oral fluids in PEDV surveillance. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 177.


• Rotolo M, Giménez-Lirola LG, Wang C, Zimmerman J. August 2015. Actualidades en el muestreo sistemático de PRRS. Memorias XVIX Congreso Nacional de la Asociación Mexicana de Veterinarios Especialistas en Cerdos (AMVEC). León, Guanajuato, México, (unpaginated).


• Sasaki Y., Alvarez J., Sekiguchi S., Sueyoshi M., Otake S., Perez A. The spatial dynamics of porcine epidemic diarrhea (PED) spread in Miyazaki prefecture, Japan. 14th ISVEE


• Schelkopf AC, Magstadt DR, Arruda BL, Arruda PHE, Zimmerman JJ, Wetzell T, Dee SA, Madson DM. November 2015. Lactogenic protection against porcine epidemic diarrhea virus in piglets following homologous challenge. Proc 2015 ISU James D McKean Swine Disease Conference, Iowa State University. Ames, Iowa, pp. 41-44.


• Schumacher LL, Cochrane RA, Woodworth JC, Stark CR, Jones CK, Chen Q, Main RG, Zhang J, Gauger PC, Dritz SS, Tokach MD. March 2015. Utilizing feed sequencing to decrease the risk of porcine epidemic diarrhea virus (PEDV) cross-contamination during feed manufacturing. Proc Midwest American Society of Animal Science. Des Moines, Iowa.


• Schumacher LL, Cochrane RA, Woodworth JC, Stark CR, Jones CK, Chen Q, Main RG, Zhang J, Gauger PC, Dritz SS, Tokach MD. March 2015. Evaluating the effect of manufacturing porcine epidemic diarrhea virus (PEDV)-contaminated feed on subsequent feed mill environmental surface contamination. Proc Midwest American Society of Animal Science. Des Moines, Iowa.


• Schumacher LL, Woodworth JC, Zhang J, Gauger PC, Chen Q, Welch M, Salzebrenner H, Thomas J, Main RG, Dritz SS, Cochrane RA, Jones CK. March 2015. Determining the minimum infectious dose of porcine epidemic diarrhea virus in a feed matrix. Midwest American Society of Animal Science. Des Moines, Iowa, Abstr#160.


• Schweer WP, Schwartz K, Yoon KJ. March 2015. A PRRS-PED virus co-infection reduces total tract digestibility in grower pigs. Midwest American Society of Animal Science. Des Moines, Iowa, Abstr#103.


• Setness, B., J. Bjustrom-Kraft, K. Woodard, L. Giménez-Lirola, Y. Sun, P. Lasley, Q. Chen, J. Zhang, E. Nelson, D. Baum, P. Gauger, J. Zimmerman, R. Main. Do sows and gilts previously infected with PEDV respond to PEDV vaccination? 2015 AASV.


• Shang P, Y Li, D Shyu, A Carrillo, P Naraghi-Arani, G J Renukaradhya, J Henningson, Y Fang. 2015. Attenuation of porcine reproductive and respiratory syndrome virus (PRRSV) by inactivating the ribosomal frameshifting products nsp2TF and nsp2N: Implication for the rational design of vaccines. NA PRRS Symposium, Chicago, IL.


• Shang P, Y Li, D Shyu, A Carrillo, P Naraghi-Arani, G J Renukaradhya, J Henningson, Y Fang. 2015. Attenuation of porcine reproductive and respiratory syndrome virus (PRRSV) by inactivating the ribosomal frameshifting products nsp2TF and nsp2N: Implication for the rational design of vaccines. Conference of Research Workers in Animal Diseases, Chicago, IL.


• Shi, K. and Yoo, D. 2014. Inhibition of type I interferon induction by nonstructural proteins of porcine epidemic diarrhea virus. 95th CRWAD Chicago, IL Dec 7-9.


• Shi, K. and Yoo, D. 2014. Inhibition of type I interferon induction by non-structural proteins of porcine epidemic diarrhea virus. 95th CRWAD, Chicago, IL Dec 7-9.


• Shi, K., Zhang, Q., and Yoo, D. 2014. Suppression of type I interferon response by nonstructural protein 1 of PEDV through degradation of CREB-binding protein. 2014 North American PRRS Symposium. Chicago, IL Dec 5-6.


• Shyu D, Li Y, Ouyang K, Dhakal S, Hireamt J, Binjawadagi B, Shang P, Fang Y, Renukaradhya GJ. 2015. Characterization of recombinant PRRSV nsp1beta mutants in a nursery pig model. Conference of Research Workers in Animal Diseases, Chicago, IL.


• Singrey, A., S. Lawson, F. Okda, K. Hain, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of monoclonal antibodies and other reagents for detection of porcine deltacoronavirus (PDCoV). 2014 NA PRRS Symp. p.53.


• Singrey, A., S. Lawson, F. Okda, K. Hain, T. Clement, J. Christopher-Hennings, E.A. Nelson. Development of monoclonal antibodies and other reagents for detection of porcine deltacoronavirus (PDCoV). 95th CRWAD 2014. 083P.


• Souza CK, Rajao DS, Loving CL, Gauger PC, Vincent AL. April 2015. The impact of adjuvant in whole inactivated virus vaccines on vaccine-associated enhanced respiratory disease in pigs following influenza a virus challenge. Proc 3rd International Symposium on Neglected Influenza Viruses. Athens, Georgia, p. 10.


• Souza, C.K., Rajão, D.S., Loving, C.L., Gauger, P.C., Vincent, A.L. 2015. The impact of adjuvant in whole inactivated virus vaccines on vaccine-associated enhanced respiratory disease in pigs following influenza A virus challenge. 3rd Neglected Influenza Symposium, Athens, Georgia.


• Sparks J, Day D, Karriker L, Wulf L, Zhang J, Bates J, Ellingson J, Gehring R, Coetzee J. March 2015. Vaccination mitigates the effect PRRSV has on the pharmacokinetics of ceftiofur crystalline free acid in pigs. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida.


• Taplett A, Burrough ER. March 2015. Correlation of semi-quantitative reverse transcription polymerase chain reaction assay results for porcine epidemic diarrhea virus and the presence of positive immunohistochemistry. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 109 – 111.


• Thachil A, Xiao CT, Gerber PF, Halbur PG, Huang YW, Opriessnig T. December 2014. Development and validation of an indirect porcine deltacoronavirus (PDCoV) anti-IgG ELISA based on the S1 portion of the spike protein and confirmation that PDCoV infection in U.S. pigs is low and has been present since 2010. Proc 95th Ann Meet Conference of Research Workers in Animal Diseases. Chicago, Illinois. Abstr #170.


• Thomas JT, Chen Q, Gauger PC, Madson D, Burrough ER, Magstadt DR, Salzbrenner H, Welch MW, Giménez-Lirola LG, Yoon KJ, Zhang J. March 2015. Effect of porcine epidemic diarrhea virus infectious doses on outcomes of infection in naïve neonatal piglets and weaned pigs. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 101-104.


• Thomas M, Z. Wang, C.C. Sreenivasan, B.M. Hause, G.J. Renukaradhya, F. Li, D.H. Francis, R.S. Kaushik and M. Khatri. Poly I:C adjuvanted inactivated swine influenza vaccine induces heterologous protective immunity in pigs. Abstract #177, 95^th Annual CWRAD meeting, December 7-9, 2014, Chicago, IL.


• Tigran Markosyan1*, Khachik Sargsyan1, Satenik Kharatyan1, Hasmik Elbakyan1, Varduhi Hakobyan1, Liana Simonyan1, Henrik Voskanyan1, Ashkhen Shirvanyan2, Tatul Stepanyan2, Marianna Khachatryan2, Melanya Karapetyan3, Armen Avagyan3, Richard Weller4 and Guillermo Risatti5 (2015). 1Scientific Centre for Risk Assessment and Analysis in Food Safety Area, SNCO, Republic of Armenia. 2Ministry of Agriculture of the Republic of Armenia; 3Veterinary Services Center, Republic of Armenia; 4 Fundamental Computational and Sciences Division, Pacific Northwest National Laboratory, USA ; 5 Department of Pathobiology and Veterinary Science, College of Agriculture, Health and Natural Resources, University of Connecticut, USA. The epidemiological status of African swine fever in domestic swine herds in the Tavush Marz region, Republic of Armenia. CRWAD Meeting 2015, Chicago, IL.


• Titov I., Malogolovkin A., Burmakina G., Syndryakova I., Katorkin S., Mima K., Kudryashov D., Gogin A., Kolbasov D. Tracking of African swine fever outbreaks through variation of intergenic 173R/ 1329L region // Xth International Congress for Veterinary Virology. 9th Annual Meeting of EPIZONE. – Montpellier;France, 2015.- P.123-124.


• Tuggle CK, Rajao DS, Loving CL, Gauger PC, Waide E, Dekkers J, Vincent AL. January 2015. Inability of severe combined immune deficient (SCID) pigs to control IAV replication despite innate immune activation. Immunity to Veterinary Pathogens: Informing Vaccine Development (A3). Keystone, Colorado, p. 77.


• Tuggle, C.K., Rajao, D., Loving, C.L., Gauger, P.C., Waide, E., Dekkers, J., Vincent, A.L. 2015. Inability of severe combined immune deficient (SCID) pigs to control IAV replication despite innate immune activation. Keystone Symposia: Immunity to Veterinary Pathogens: Informing Vaccine Development (A3), Keystone, Colorado.


• VanderWaal, K., & Kinsley, A. (2015). An epidemiological model of Foot-and-mouth disease. Invited oral presentation at: Symposium on the epidemiology of foot-and-mouth-disease in swine, Allen D. Leman Conference. St. Paul, MN.


• Vannucci, FA, Marthaler, D. (2015). Lessons learned on investigation of vesicular disease in swine. Leman Conference 2015, Sept 21, Saint Paul, MN.


• Vergne T, Combelles L., Korennoy F., Gogin A., Pfeiffer D.U. Where to look for African swine fever in the Russian Federation? Identifying disease risk factors while accounting for under-detection. / SVEPM Annual Conference 2015.


• Vergne T, Gogin A, Pfeiffer D.U. Local transmission routes of African swine fever in pigs in the Russian Federation: do wild boars matter? / SVEPM Annual Conference 2015.


• Vergne T., Korennoy F., Combelles L., Gogyn A., Pfeiffer D. Using incomplete data to characterise the risk of African swine fever in the Russian Federation, 2007-2014. - Poster SVEPM 2015


• Vincent, A.L., Rajao, D.S., Abente, E.J., Walia, R., Anderson, T.K., Lewis, N.S. 2015. Current state of influenza A virus in U.S. swine. Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting, Rochester, New York.


• Vitosh-Sillman, S., C. Kelling, B. Brodersen, J. Loy, A. Doster, C. Topliff, E. Nelson, J. Bai, E. Schirtzinger, E. Poulsen, B. Meadors, D. Hesse. Histopathological and immunohistochemical characterization of pigs experimentally infected with porcine deltacoronavirus. 2015 AASV.


• Vitosh-Sillman, S., C. Kelling, B. Brodersen, J. Loy, A. Doster, C. Topliff, E. Nelson, J. Bai, E. Schirtzinger, E. Poulsen, B. Meadors, D. Hesse. Porcine Deltacoronavirus—Koch’s Postulates Fulfilled. 2014 NA PRRS Symp. p.27.


• Walia, R.R., Stratton, J.A., Anderson, T.K., Vincent, A.L. 2015. Spatial and temporal patterns in the diversity of swine influenza A viruses collected by the USDA Surveillance System. Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting, Rochester, New York.


• Wang Y, R Guo, R Ransburgh, J Hill, J Henningson, W Zhang, Y Fang. 2015. Characterization and application of monoclonal antibodies against porcine epidemic diarrhea virus. NA PRRS Symposium, Chicago, IL.


• Wang Y, R Guo, R Ransburgh, J Hill, J Henningson, W Zhang, Y Fang. 2015. Characterization and application of monoclonal antibodies against porcine epidemic diarrhea virus. Conference of Research Workers in Animal Diseases, Chicago, IL.


• Yoo, D. 2014. Innate immunity to PRRSV and application to new vaccines. 2014 North American PRRS Symposium. Chicago, IL Dec 5-6.


• Yoo, D., Han, M. 2015. Nuclear retention of host cell transcripts by nonstructural protein (nsp) 1 of arteriviruses and suppression of host innate immunity. 2015 International PRRS Congress. Ghent, Belgium, June 3-5.


• Yoo, D., Han, M., Ke, H. 2015. Subversion of host protein synthesis by PRRS virus nonstructural protein (nsp) 1β. 2015 International PRRS Congress. Ghent, Belgium, June 3-5.


• Zhang J, Chen Q, Chriswell A, Dunn D, Li G, Sinha A, Thomas J, Harmon K, Gauger P. March 2015. PEDV sequencing: Does it really matter? 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida. Seminar #2, pp. 27-32.


• Zhang J, Chen Q, Gauger P, Thomas J, Giménez-Lirola LG, Li G, Madson D, Burrough E, Harmon K, Yoon KJ, Zimmerman J, Main R. June 2015. Genetic and phenotypic characterization of U.S. porcine epidemic diarrhea viruses. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 48.


• Zhang J, Chen Q, Gauger P, Thomas J, Giménez-Lirola LG, Li G, Madson D, Burrough E, Harmon K, Yoon KJ, Zimmerman J, Main R. June 2015. Genetic and phenotypic characterization of U.S. porcine epidemic diarrhea viruses. Proc International Symposium on Emerging and Re-Emerging Pig Diseases. Kyoto Japan, p. 48.


• Zhang J, Chen Q, Gauger P, Thomas J, Welch W, Madson D, Magstadt D, Burrough E, Arruda P, Derscheid R. March 2015. Comparison of the pathogenesis differences of the U.S. PEDV prototype and variant strains in neonatal piglets. Proc 46th Annual Meeting of the American Association of Swine Veterinarians. Orlando, Florida, pp. 49-51.


• Zhang J, Chen Q, Thomas J, Gauger P, Giménez-Lirola L, Yoon KJ, Madson D, Li G, Burrough E, Harmon K, Hoang H, Sun D, Bhandari M, Stevenson G, Zimmerman J, Baum D, Main R. December 2014. PEDV in the U.S.: diagnostic tools and research applications in diagnostics. Proc 2014 North American PRRS Symposium. Chicago, Illinois, p. 38.


• Zhang J, Zhang Y, Chen Q, Tsai YL, Chiang CJ, Shen YH, Li FC, Lee PY, Chang HF, Gauger PC, Harmon KM, Want HT. October 2015. Development and evaluation of two singleplex reverse transcription-insulated isothermal PCR tests and a duplex real-time RT-PCR test for the detection of porcine epidemic diarrhea virus and porcine deltacoronavirus. Proc 58th Annual Conference, American Association of Veterinary Laboratory Diagnosticians. Providence, Rhode Island, p. 136.


• Zimmerman J, Giménez-Lirola L, Wang C, Main R, Roth JA. December 2014. Preparing for the next incursion: efficient, cost-effective on-farm surveillance. Proc 2014 North American PRRS Symposium. Chicago, Illinois, p. 39.


• Zimmerman J, Giménez-Lirola LG, Main R. May 2015. Avances en vigilancia de enfermedades de cerdos. Proc II Seminario Internacional de Sanidad Agropecuaria, "Avances y Retos de la Sanidad Agropecuaria en el Siglo XXI", II Taller "Vacunas y Diagnóstico Veterinario". Varadero, Cuba, SA-O13.


• Zimmerman J, Rotolo M, Giménez-Lirola L, Wang C, Main R. October 2015. Detecção e prevenção das doenças emerentes em suinos. Anais do 17º Congresso da Associação Brasileira de Médicos Veterinários Especialistas em Suínos (ABRAVES). Campinas (Sao Paulo), Brazil, pp. 62-67 (Vol 1).


• Zimmerman J. June 2015. Skuteczny monitoring w erze zagrożeń nowymi chorobami zakażnymi (Effective surveillance in an era of emerging infectious diseases). Proc XX Jubileuszowa Międzynarodowa Konferencja Naukowa, “Krytyczne obszary w produkcji świń” (XX Jubilee International Scientific Conference, “Critical areas in the production of swine”). Pulawy, Poland, pp. 32-33.


• Zuckermann, F.A., Calzada‐Nova, G., Husmann, R., and Villamar, M. 2014. Assessment of cross‐protective immunity elicited by a novel PRRS live virus vaccine against a highly virulent type 2 PRRS belonging to lineage 1. Department of Pathobiology, University of Illinois at Urbana‐ North American PRRS Symposium. Chicago, IL, Dec 7-8

 

 

• Book chapters or monographs

 

• Ramirez A. 2015. Guía del PRRS – Síndrome Reproductivo y Respiratorio Porcino. Zaragoza, Spain: SERVET. ISBN: 978-84-16315-20-8.


• Guidelines for classification of phases and types of an African swine fever outbreak and response: http://www.securepork.org/african-swine-fever.php


• Guidelines for classification of phases and types of a classical swine fever outbreak and response: http://www.securepork.org/classical-swine-fever.php


• FAD PReP NAHEMS Guidelines: Vaccination for Contagious Diseases, Appendix A: Vaccination for Foot and Mouth Disease: http://www.cfsph.iastate.edu/pdf/fad-prep-nahems-appendix-a-vaccination-for-foot-and-mouth-disease.


• Zhang J, Gauger P, Harmon K. Swine influenza A virus. In: Molecular Detection of Animal Viral Pathogens, Dongyou Liu (ed). CRC Press, Boca Raton (in press).


• Loving C, Osorio FA, Murtaugh MP, Zuckermann FA. 2015. Innate and adaptive immunity against porcine reproductive and respiratory syndrome virus. Vet. Immunol. Immunopath. 167:1-14.


• Torremorell M (2015). Immunity, diagnosis and intervention strategies of influenza infections in pigs. In: Animal Influenza. Ed. David Swayne, 2nd Edition. Wiley Publisher, (In press)


• Travis DA, Sriramarao P, Cardona C, Steer CJ, Kennedy S, Sreevatsan S, Murtaugh MP. 2014. One Medicine One Science: a framework for exploring challenges at the intersection of animals, humans and the environment. Ann NY Acad Sci. 1334:26–44.


• Ma, Y. Yu, T. Opriessnig, L. Yang, Y. Nan, P. Halbur, and Y. Zhang: Interferon Induction of a PRRSV Strain Sustained After Serial Passaging. 2014 PRRS Symp.

 

 

 

1. FUNDING SOURCES FOR SWINE VIROLOGY RESEARCH – Current

 

• Ying Fang and Renukaradhya Gourapura (Co-PI). Innovative strategies to enhance PRRSV specific innate and mucosal immunity: implication for development of broadly protective PRRSV vaccine. USDA-AFRI, February 2012 – February 2017 .


• Lawson, S., A. Singrey, T. Clement, D. Diel, J. Christopher-Hennings, E.A. Nelson. Development of reagents and serological assays for Seneca Valley Virus. Swine Health Information Center. $33,820, 10/15 to 4/16.


• Diel, D., T. Clement, E.A. Nelson, J. Christopher-Hennings, L. Caron, R. Shaefer. Characterization of Seneca Valley Virus circulating in the U.S. and Brazil. Swine Health Information Center. $63,701, 10/15 to 4/16.


• Singrey, A., C. Clement, E.A. Nelson. Evaluation of PEDV stability on shipping totes. USDA-APHIS, $19,577, 4/15 to 3/16.


• Ramamoorthy, S., B. Webb, P. Nara, E. Nelson. Designing epitope-based Vaccines to improve efficacy and detection. USDA NIFA-AFRI. $149,936, 6/1/15 to 5/30/17.


• Diel, D., E.A. Nelson. Production and characterization neutralizing monoclonal antibodies against PEDV and PDCoV. Boehringer-Ingelheim Vetmedica. $83,620. 2/15 to 12/15.


• Wang, D., E.A. Nelson, R. Kaushik, F. Li. Novel porcine epidemic diarrhea virus vaccine pipeline. USDA AFRI $149,832, 1/16 to 12/17.


• Diel, D.G., E.A. Nelson, Christopher-Hennings, J., Pillatzki, A. Development of a multivalent vector platform to control swine enteric coronavirus disease. National Pork Board. $73,713. 5/15-4/16.


• Diel, D., H. Vu, F. Osorio, E.A. Nelson, J. Christopher-Hennings. Evaluation of immunodominant B- and T-cell epitopes as inducers of protective immunity against porcine reproductive and respiratory syndrome virus. National Pork Board. $83,094. 10/14 to 4/16.


• Levesque, C.L., Brown, M., Gibbons, W., Diel, D.G., Kaushik, R. Evaluation of a microbially-converted soybean meal on nursery pig immune status and disease resistance. South Dakota Soybean and Promotion Council FY15-FY17. $153,500


• Nelson, E.A., S. Lawson, A. Singrey, T. Clement, J. Christopher-Hennings. Development of reagents and serological assays for Porcine Deltacoronavirus (PDCoV). National Pork Board. $29,390. 6/14 to 12/14.


• Clement, T., A. Singrey, S. Lawson, J. Christopher-Hennings and E.A. Nelson. Duration and level of PEDV neutralizing antibodies for clinical protection using feedback protocols. National Pork Board. $48,750. 12/13 to 12/14.


• Nelson, E.A., A. Singrey, S. Lawson, T. Clement and J. Christopher-Hennings. PEDV diagnostic approaches to assess sow immunity and piglet protection. National Pork Board. $41,900. 5/14 to 4/15.


• Thaler, B., C. Lavesque, J. Christopher-Hennings, E. Nelson, J. Clapper. Efficacy of soybean meal in reducing the effect of a PRRSV challenge in pigs. South Dakota Soybean and Promotion Council FY15. $131,074. 7/14 to 7/15.


• Wang, X., E.A. Nelson. Determining Virus-Like Particle (VLP) Feasibility for New Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Vaccines. $150,000. USDA AFRI NIFA. 5/12 to 4/15.


• Nelson, E.A., J. Christopher-Hennings, Y. Fang. Improved methods for the diagnosis of porcine reproductive and respiratory syndrome and other important diseases of swine. SDSU AES Hatch. 3/11 to 9/16.


• Christopher-Hennings, J., D. Diel and E.A. Nelson. Detection and control of porcine reproductive and respiratory syndrome virus and emerging viral diseases of swine. SD AES NC-229 Multi-State Project. 10/14 to 10/19.


• Diel D.G., Nelson, E.A., Christopher-Hennings, J., Lawson, S. Improved Strategies for Prevention and Control of Viral Diseases of Livestock. SD AES-Hatch 10/14-09/19.


• Osorio FA, Pattnaik AK, Kauvar L. Molecular Structures of Porcine Reproductive and Respiratory Virus (PRRSV) that Contribute to Protective Immunity USDA-AFRI-NIFA 2013-01035 (Animal Health and Production and Animal Products: Animal Health and Disease) $499,999 09/1/2013-08/31/2016 Role Goal: ascertaining which epitopes induce broadly PRRSV- neutralizing antibodies


• Pattnaik AK, Osorio FA Development of a Novel Self-Propagating PRSSV-VSV G Hybrid Replicon as a Vector for Inducing Broad PRRSV Protection National Pork Board $200,000 12/1/13 -11/30/15


• Vu H, Osorio FA Development of a live-attenuated PRRSV vaccine capable of eliciting a broad spectrum of heterologous protection. National Pork Board. 2015/10/01 – 2016/09/30 $96,880.


• Diel, D, Vu H, Nelson E, C-Hennings, J, Osorio FA Evaluation of immune-dominant B- and T-cell epitopes as inducers of protective immunity against porcine reproductive and respiratory syndrome virus. National Pork Board 2014/10/01-2015/09/30 $26,945 ( amounts corresponds to NE sub-award assigned to H Vu)


• Vu, H (PI) Osorio FA (Co-PI) Determine the correlates of protection against porcine reproductive and respiratory syndrome viruses infection USDA-AFRI-NIFA #2015-06921 period: 2016/01/01- 2018/12/31Total $ 477,635


• Brockmeier, Faaberg, Lager, Miller, Loving, Vincent - USDA ARS Research Funds


• Sang, Rowland, Blecha, Miller – NIFA-AFRI - Antiviral regulation underlying the activation status of porcine monocytic innate immune cells


• Faaberg, Pegan – National Pork Board - Role of the viral ovarian domain protease in PRRSV pathogenesis


• Lager - Animal And Plant Health Inspection Service (APHIS), U.S. Department of Agriculture - Emerging Swine Disease Studies: Porcine Epidemic Diarrhea Virus (PEDV)


• Lager - Animal And Plant Health Inspection Service (APHIS), U.S. Department Of Agriculture - Identify Mechanisms of Viral Pathogenesis, Transmission, and Immunity of Porcine Epidemic Diarrhea Virus and Other Emerging Swine Coronaviruses


• Lager - Merck and Company - Challenge of PRRS Vaccine Immunity in Swine


• Vincent - Animal And Plant Health Inspection Service (APHIS), U.S. Department of Agriculture -USDA Swine Influenza Virus Surveillance System: Computational Evolutionary Biology Of Whole Genome Sequences.


• Vincent – NIH, National Institute of Allergy and Infectious Diseases, Department of Health and Human Services - Characterization of the Evolution of Influenza A Viruses (IAV) in Swine and Pathotyping of IAV in the Natural Host


• Vincent - Animal and Plant Health Inspection Service (APHIS), U.S. Department of Agriculture - USDA Swine Influenza A Virus Surveillance System: Extension to: In Vivo Pathogenesis and Transmission and Associated In Vitro Studies


• Fang, Y., Rowland R. Bai J. Adaptation of Lawrence Livermore Microbial Detection Array System at Kansas State University. K-State college of veterinary medicine intramural fund, 01/01/2016-12/31/2016, $29,773.


• Biao, H., Y. Fang. Developing a Parainfluenza Virus 5 (PIV5)-based PRRS Vaccine. USDA-NIFA, 1/1/2016 – 12/31/2018, $450,000.


• Hause, B., Y. Fang. Determination of the PRRSV Miner Glycoproteins Contribution to Antigenicity and Protection. National Pork Board; 10/1/2015 – 9/30/2016, $69,080.


• Fang, Y., G. Anderson. Generation of Reagents for differentiation of swine pathogens. private company, 04/01/2015-03/31/2016, $150,000.


• Fang, Y. Evaluation of Safety and Immunogenic Response Live Porcine Epidemic Diarrhea Virus (PEDV) Vaccines in Pigs. Private company, 6/11/2015 – 3/10/2016, $28,670.


• Yang HC. Major Program of National Natural Science Foundation of China (31490603)

The earmarked fund for Modern Agro-industry Technology Research System of China (CARS-36) from the Ministry of Agriculture of the People’s Republic of China.

• Yang HC. National Basic Research Program of China 481 (2014CB542700) from the Chinese Ministry of Science and Technology


• Yang HC. Key Program of National Natural Science Foundation of China (31330077)


• Huber, V., Y. Fang, H. Biao. A candidate swine influenza virus vaccine: in vivo evaluation of novel chimeric hemagglutinins expressed by parainfluenza virus 5 vector. National Pork Board, 05/01/2015-04/30/2016, $88,888.


• Fang, Y. A novel arterivirus protein and expression mechanism: implication in vaccine and companion diagnostic assay development. USDA-NIFA 2014-06403, 01/01/2015 – 12/31/2019, $472,179.                                                            


• Fang, Y. In vitro evaluation of an improve PRRS vaccine. Private company, 12/01/2014-11/30/2015, $86,085.


• Fang, Y. In vivo evaluation of a parainfluenza virus 5 (PIV5)-vectored candidate PRRS vaccine University of Georgia Research Fundation, 07/01/2014 – 06/30/2015, $21,430.67.


• Fang, Y. Development of vaccines against porcine epidemic diarrhea virus. K-State Research Foundation, 07/14/2014 – 03/15/2015, $14,400.


• Fang, Y., R. Gourapura, W. Zhang, J. Christopher-Hennings, E. Nelson. Innovative strategies to enhance PRRSV specific innate and mucosal immunity. USDA-NIFA, 2012-67015-21823, 05/01/12-04/30/17, $499,366.


• Rowland NBAF Transition Funding for the study of ASF, RVF and CSF, 2014-2015, $1.2 million.


• Yoo, Rowland, USDA NIFA 2013-2017, Immune evasion of PRRS virus and a novel strategy for vaccine development, 2013-2017, approximately $60,000 to the Rowland lab.


• Dekkers, Rowland, Lunney, et al., USDA NIFA, 2012-2017, Genetically Improving Resistance of Pigs to PRRS Virus Infection, $3 million, approximately $800,000 to the Rowland lab.


• Patience et al., 2010-2015, USDA-NIFA, Improving biological nutrient use and thus feed efficiency in the U.S. pork industry through innovative scientific and extension approaches for a more sustainable production, $65,000.


• Rowland et al., 2010-2015, Specific Cooperative Agreement: KSU and USDA-ARS-ABADRU, $400,000.


• Yoo, D. (2013-2018), USDA NIFA-AFRI, $500,000, Immune evasion of PRRS virus and a novel approach to vaccine design.


• Renukaradhya Gourapura (PI). Evaluation of mucosal B cell response to PEDV in infected sows. National Pork Board, June 2014 – June 2015


• Chang Won Lee and Renukaradhya Gourapura (Multi-PIs). Universal Flu Vaccine by a Norovirus P Particle Platform. USDA-AFRI, January 2013-2018.


• Renukaradhya Gourapura (PI). Field trials on nanoparticle-based inactivated porcine reproductive and respiratory syndrome (PRRS) virus vaccine in growing pigs. OARDC, OSU Matching Grant Award, June 2014 – May 2016.


• Renukaradhya Gourapura (PI), Chang Won Lee and Balaji Narasimhan. Evaluation of mucosal Th1-Th2 balanced response inducing nanovaccine against swine influenza virus. Iowa State University - Nanovaccine Research Initiative, September 2014 – June 2016.


• Renukaradhya Gourapura (PI), Santosh Dhakal and Shauna Brummet. Broadly Protective Swine Influenza Vaccine. I-Corps@Ohio (Innovation Corps) Program, The Ohio State University, July 2015 to December 2015.


• Renukaradhya Gourapura (PI). Analysis of candidate porcine reproductive and respiratory syndrome virus vaccine development. USDA-FAS Borlaug International Fellowship Program, September 2015 to December 2015.


• Renukaradhya Gourapura (PI) and Eluemuno Blyden (AfriVAx). Bulk production of recombinant porcine reproductive and respiratory syndrome viral antigens in embryonated chicken eggs to use in a vaccine. Small Industry and OARDC Matching SEED Grant, June 2014 – Oct 2015.


• ASForce – Targeted research on African swine fever (7th - EU-FP)(Russia Report)


• USDA grant - Identification of African swine fever protection antigen(Russia Report)


• IAEA project - Research of African Swine Fever (ASF) Diagnosis and Research - Early and Rapid Diagnosis and control of TAD’s;(Russia Report)


• Gauger P, Zhang J, Magstadt D. Evaluation of cross-protection in Fostera™ PRRSV vaccinated conventional swine challenged with a contemporary, heterologous lineage 1 PRRSV. Zoetis.


• Hatch Project, Storrs Agricultural Experiment Station.


• Polyvalent T cell Mosaic Vaccine to Cross-Protect Swine against Heterologous PRRSV Strains. USDA/NIFA Grant Number 2011 67015-30176.


• Gimenez-Lirola L, Zhang J, Zimmerman J, Gauger P, Madson D, Main R, Baum D. Generation of specimens of precisely known coronavirus infection status for the development and validation of highly-specific porcine coronavirus antibody assays. Iowa Pork Producers Association.


• Holtkamp D, Thomas P, Ramirez A, Karriker L, Zhang J. Evaluation of an accelerated hydrogen peroxide disinfectant and barn lime to inactivate porcine epidemic diarrhea virus in swine packing plant dock and unloading areas. Iowa Pork Producers Association.


• Holtkamp D, Thomas P, Ramirez A, Karriker L, Zhang J. Evaluation of an accelerated hydrogen peroxide disinfectant to inactivate porcine epidemic diarrhea virus in swine feces on metal surfaces under freezing conditions. National Pork Board.


• Holtkamp DJ, Canon A, Karriker L. Development of PRRS outbreak investigation and data management/analysis program for breeding herds in regional PRRSV projects in Iowa. Iowa Pork Producers Association.


• Holtkamp DJ, Linhares DC. Monitoring and updating the value of productivity losses due to porcine reproductive and respiratory syndrome virus.


• Karriker L. Effect of Calsporin on intestinal health parameters after PEDv challenge. QTI/Calpis International.


• Lager K, Karriker L. Evaluating the epidemiology, ecology, and biology of swine viral pathogens. USDA ARS.


• Li G. Whole genome sequencing of PEDv from fecal samples. USDA NAHLN Program Office.


• Madson D, Yoon KJ, Kuster C, Zhang J. Porcine epidemic diarrhea virus disease progression and shedding in mature boars post oral feedback inoculation. Iowa Pork Producers Association.


• Madson D, Zhang J, Halbur P. AgriLabs porcine epidemic diarrhea virus egg antibody investigation. AgriLabs Ltd.


• Main R, Rossow S, Gauger P, Harmon K, Marthaler D, Vannucci F, Zhang J. Expedited look into the prevalence of Senecavirus A in US swine. Swine Health Information Center.


• Matzinger and Meng XJ. USDA-NIFA-2013-03314 S. 09/01/2013-08/31/2015. PCV2 non-coding RNA and their effects on the host immune response and pathogenesis


• Meng XJ, S. Subramaniam and T. Opriessnig. USDA-NIFA-2013-67015-21342. 09/01/2013 -08/31/2017 Enhancing CMI responses for PRRSV vaccine development


• Meng XJ, E. Subbiah. USDA-NIFA-2012-67015-19469. 5/1/2012 - 4/30/2016A multicomponent virus vectored vaccine for PRRSV, PCV2 and swine influenza


• Overend and Meng XJ. USDA-NIFA-2015-67012-22768C. 12/15/2014 –


• 12/14/2016. Development of a novel PRRSV vaccine engineered to enhance antigen presentation


• Piñeyro PE, Giménez-Lirola L, Burrough E, Derscheid RJ, Madson D, Zhang JQ. Development of direct detection methods for in situ diagnosis of Seneca A virus. Swine Health Information Center.


• Ramamoorthy S. USDA-NIFA, ND Dept. of Commerce Venture Awards, N. Dakota Agricultural Products Utilization Committee.


• Roth J, Bickett Weddle D, Dvorak G, Mogan King J, Flaming K, Zaabel P. Secure milk and secure pork supply projects for business continuity in a foreign animal disease outbreak. USDA APHIS.


• Hatch Multistate Project, NC229. Storrs Agricultural Experiment Station.


• Roth J, Trampel D, Bickett-Weddle D, Mogan-King J, Flaming K, Zaabel J, Leedom LK. Secure food supply projects for business continuity in a foreign animal disease outbreak (eggs, turkey, milk, pork). USDA APHIS.


• Roth J, Zaabel P. A review of commercial influenza vaccines available for use in pigs. USDA APHIS.


• Roth J. Development of a transboundary swine disease information resource. Swine Health Information Center.


• Roth J. Implementation of the Secure Pork Supply Plan. National Pork Board.


• Roth J. Secure food supply projects for business continuity in a foreign animal disease outbreak. USDA APHIS.


• Roth J. Swine Influenza A virus surveillance system project. USDA ARS.


• Woodworth J, Stark C, Main R, Zhang J, Jones C, Gauger P, Dritz S, Tokach M. Utilizing feed sequencing as a biosecurity intervention for preventing PEDV cross-contamination in the feed manufacturing process. National Pork Board.


• Zhang J, Chen Q, Gauger P, Li G, Main R. Evaluation of attenuation phenotypes of cell culture-adapted PEDV in neonatal piglets. Iowa State University College of Veterinary Medicine Seed Grant and USDA Formula Grant.


• Zhang J, Chen Q, Gauger P, Madson D. Evaluation of the pathogenesis differences of PEDV original and variant strains and examination of the cross-protective immunity between two strains. Iowa Pork Producers Association.


• Zhang J, Chen Q, Gauger P. In vitro evaluation of serological cross-reactivity and cross-neutralization between the PEDV original and variant strains. Zoetis.


• Zhang J, Gauger P, Burrough E, Madson D, Giménez-Lirola L, Yoon KJ. Effect of porcine epidemic diarrhea virus infectious doses on outcomes of infection in naïve neonatal piglets and weaned pigs. Iowa Pork Producers Association.


• Zhang J, Gauger P, Li G, Main R. Development and evaluation of a live attenuated porcine epidemic diarrhea virus vaccine. Zoetis.


• Yoon K-J, Adelman JS, Sato Y, Blanchong J, Gauger P, Zhang J, Li G, Main R, Beilke E, Canon A, Colboth E, Widsom J. Role of terrestrial wild birds, rodents and insects in spreading avian influenza virus into commercial layer operations. Egg Industry Center, $119,866.


• Xin H, Zhao, Y, Yoon K-J. Airborne transmission of highly pathogenic avian influenza virus in the poultry industry and the role of dust as a carrier. USDA NIFA AFRI Exploratory Research Program, $100,000.


• Xu W, Yoon K-J, Cho MW, Rock DL. 7/1/15-/30/16. Development of T-cell based vaccine against African swine fever virus. Center of Excellence for Emerging and Zoonotic Animal Diseases, $79,977.


• Miller C, Yoon KJ. 7/1/15-6/30/17. Development of novel reovirus-based mucosal vaccine vectors for PEDV antigen production. Iowa Pork Producers Association, $25,000 for 1^st

11/15/2017

Refereed publications by NC229 participants

 

PRRS virus:

1. Sun Y, Ke H, Han M, Chen N, Fang W, Yoo D. Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Suppresses Both MAVS and RIG-I Expression as One of the Mechanisms to Antagonize Type I Interferon Production. PLoS One. 2016 Dec 20;11(12):e0168314. doi: 10.1371/journal.pone.0168314.eCollection 2016. PubMed PMID: 27997564; PubMed Central PMCID: PMC5172586.


2. Piñeyro PE, Subramaniam S, Kenney SP, Heffron CL, Giménez-Lirola LG, Meng XJ. Modulation of Proinflammatory Cytokines in Monocyte-Derived Dendritic Cells by Porcine Reproductive and Respiratory Syndrome Virus Through Interaction with the Porcine Intercellular-Adhesion-Molecule-3-Grabbing Nonintegrin. Viral Immunol. 2016 Dec;29(10):546-556. Epub 2016 Sep 19. PubMed PMID: 27643915.


3. Sun H, Pattnaik AK, Osorio FA, Vu HLX. Identification of viral genes associated with the interferon-inducing phenotype of a synthetic porcine reproductive and respiratory syndrome virus strain. Virology. 2016 Dec;499:313-321. doi: 10.1016/j.virol.2016.09.018. Epub 2016 Oct 11. PubMed PMID: 27736706.


4. Evenson D, Gerber PF, Xiao CT, Halbur PG, Wang C, Tian D, Ni YY, Meng XJ, Opriessnig T. A porcine reproductive and respiratory syndrome virus candidate vaccine based on the synthetic attenuated virus engineering approach is attenuated and effective in protecting against homologous virus challenge. Vaccine. 2016 Nov 4;34(46):5546-5553. doi: 10.1016/j.vaccine.2016.09.049. Epub 2016 Oct 11. PubMed PMID: 27742217.


5. Ma Z, Yu Y, Xiao Y, Opriessnig T, Wang R, Yang L, Nan Y, Samal SK, Halbur PG, Zhang YJ. Sustaining Interferon Induction by a High-Passage Atypical Porcine Reproductive and Respiratory Syndrome Virus Strain. Sci Rep. 2016 Nov 2;6:36312. doi: 10.1038/srep36312. PubMed PMID: 27805024; PubMed Central PMCID: PMC5090871.


6. Chung CJ, Cha SH, Grimm AL, Chung G, Gibson KA, Yoon KJ, Parish SM, Ho CS, Lee SS. Recognition of Highly Diverse Type-1 and -2 Porcine Reproductive and Respiratory Syndrome Viruses (PRRSVs) by T-Lymphocytes Induced in Pigs after Experimental Infection with a Type-2 PRRSV Strain. PLoS One. 2016 Oct 31;11(10):e0165450. doi: 10.1371/journal.pone.0165450. eCollection 2016. PubMed PMID: 27798650; PubMed Central PMCID: PMC5087905.


7. Schlink SN, Lager KM, Brockmeier SL, Loving CL, Miller LC, Vorwald AC, Yang HC, Kehrli ME Jr, Faaberg KS. Enhancement of innate immunity with granulocyte colony-stimulating factor did not mitigate disease in pigs infected with a highly pathogenic Chinese PRRSV strain. Vet Immunol Immunopathol. 2016 Oct 15;179:70-6.  doi: 10.1016/j.vetimm.2016.08.007. Epub 2016 Aug 10. PubMed PMID: 7590428.


8. Yu Z, Huang C, Zhang Q, Feng WH. Porcine reproductive and respiratory syndrome virus (PRRSV) induces IL-12p40 production through JNK-AP-1 and NF-κB signaling pathways. Virus Res. 2016 Oct 2;225:73-81. doi: 10.1016/j.virusres.2016.09.009. Epub 2016 Sep 20. PubMed PMID: 27663131.


9. Wang X, Yang X, Zhou R, Zhou L, Ge X, Guo X, Yang H. Genomic characterization and pathogenicity of a strain of type 1 porcine reproductive and respiratory syndrome virus. Virus Res. 2016 Oct 2;225:40-49. doi: 10.1016/j.virusres.2016.09.006. Epub 2016 Sep 13. PubMed PMID: 27619842.


10. Du L, Liu Y, Du Y, Wang H, Zhang M, Du Y, Feng WH. Porcine reproductive and respiratory syndrome virus (PRRSV) up-regulates IL-15 through PKCβ1-TAK1-NF-κB signaling pathway. Virology. 2016 Sep;496:166-174. doi: 10.1016/j.virol.2016.06.007. Epub 2016 Jun 16. PubMed PMID: 27318153.


11. Tabynov K, Sansyzbay A, Tulemissova Z, Tabynov K, Dhakal S, Samoltyrova A, Renukaradhya GJ, Mambetaliyev M. Inactivated porcine reproductive and respiratory syndrome virus vaccine adjuvanted with Montanide™ Gel 01 ST elicits virus-specific cross-protective inter-genotypic response in piglets. Vet Microbiol. 2016 Aug 30;192:81-89. doi: 10.1016/j.vetmic.2016.06.014. Epub 2016 Jul 1. PubMed PMID: 27527768.


12. Sun D, Khatun A, Kim WI, Cooper V, Cho YI, Wang C, Choi EJ, Yoon KJ. Attempts to enhance cross-protection against porcine reproductive and respiratory syndrome viruses using chimeric viruses containing structural genes from two antigenically distinct strains. Vaccine. 2016 Aug 5;34(36):4335-42. doi: 10.1016/j.vaccine.2016.06.069. Epub 2016 Jul 9. PubMed PMID: 27406935.


13. Workman AM, Smith TP, Osorio FA, Vu HL. Complete Genome Sequence of Highly Virulent Porcine Reproductive and Respiratory Syndrome Virus Variants That Recently Emerged in the United States. Genome Announc. 2016 Aug 4;4(4). pii: e00772-16. doi: 10.1128/genomeA.00772-16. PubMed PMID: 27491998; PubMed Central PMCID: PMC4974319.


14. Serão NV, Kemp RA, Mote BE, Willson P, Harding JC, Bishop SC, Plastow GS, Dekkers JC. Genetic and genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) in gilts and sows. Genet Sel Evol. 2016 Jul 14;48(1):51. doi: 10.1186/s12711-016-0230-0. PubMed PMID: 27417876; PubMed Central PMCID: PMC4944421.


15. Li L, Zheng Q, Zhang Y, Li P, Fu Y, Hou J, Xiao X. Antiviral activity of recombinant porcine surfactant protein A against porcine reproductive and respiratory syndrome virus in vitro. Arch Virol. 2016 Jul;161(7):1883-90. doi: 10.1007/s00705-016-2838-3. Epub 2016 Apr 21. PubMed PMID: 27101074.


16. Zhang L, Zhou L, Ge X, Guo X, Han J, Yang H. The Chinese highly pathogenic porcine reproductive and respiratory syndrome virus infection suppresses Th17 cells response in vivo. Vet Microbiol. 2016 Jun 30;189:75-85. doi: 10.1016/j.vetmic.2016.05.001. Epub 2016 May 3. PubMed PMID: 27259830.


17. Huang C, Du Y, Yu Z, Zhang Q, Liu Y, Tang J, Shi J, Feng WH. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors. Sci Rep. 2016 Jun 22;6:28497. doi: 10.1038/srep28497. PubMed PMID: 27329948; PubMed Central PMCID: PMC4916416.


18. Hess AS, Islam Z, Hess MK, Rowland RR, Lunney JK, Doeschl-Wilson A, Plastow GS, Dekkers JC. Comparison of host genetic factors influencing pig response to infection with two North American isolates of porcine reproductive and respiratory syndrome virus. Genet Sel Evol. 2016 Jun 20;48(1):43. doi: 10.1186/s12711-016-0222-0. PubMed PMID: 27324857; PubMed Central PMCID: PMC4915112.


19. Yuan S, Zhang N, Xu L, Zhou L, Ge X, Guo X, Yang H. Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus. PLoS One. 2016 Jun 16;11(6):e0156518. doi: 10.1371/journal.pone.0156518. eCollection 2016. PubMed PMID: 27310256; PubMed Central PMCID: PMC4911139.


20. Binjawadagi B, Lakshmanappa YS, Longchao Z, Dhakal S, Hiremath J, Ouyang K, Shyu DL, Arcos J, Pengcheng S, Gilbertie A, Zuckermann F, Torrelles JB, Jackwood  D, Fang Y, Renukaradhya GJ. Development of a porcine reproductive and respiratory syndrome virus-like-particle-based vaccine and evaluation of its immunogenicity in pigs. Arch Virol. 2016 Jun;161(6):1579-89. doi: 10.1007/s00705-016-2812-0. Epub 2016 Mar 23. PubMed PMID: 27008569.


21. Chen N, Trible BR, Kerrigan MA, Tian K, Rowland RR. ORF5 of porcine reproductive and respiratory syndrome virus (PRRSV) is a target of diversifying selection as infection progresses from acute infection to virus rebound. Infect Genet Evol. 2016 Jun;40:167-75. doi: 10.1016/j.meegid.2016.03.002. Epub 2016 Mar 4. PubMed PMID: 26961593.


22. Niederwerder MC, Jaing CJ, Thissen JB, Cino-Ozuna AG, McLoughlin KS, Rowland RR. Microbiome associations in pigs with the best and worst clinical outcomes following co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). Vet Microbiol. 2016 May 30;188:1-11. doi: 10.1016/j.vetmic.2016.03.008. Epub 2016 Mar 11. PubMed PMID: 27139023.


23. Wilkinson JM, Bao H, Ladinig A, Hong L, Stothard P, Lunney JK, Plastow GS, Harding JC. Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetus. BMC Genomics. 2016 May 20;17:383. doi: 10.1186/s12864-016-2720-4. PubMed PMID: 27207143; PubMed Central PMCID: PMC4875603.


24. Zhang L, Cui Z, Zhou L, Kang Y, Li L, Li J, Dai Y, Yu S, Li N. Developing a Triple Transgenic Cell Line for High-Efficiency Porcine Reproductive and Respiratory Syndrome Virus Infection. PLoS One. 2016 May 16;11(5):e0154238. doi:  10.1371/journal.pone.0154238. eCollection 2016. Erratum in: PLoS One. 2016 Jul 26;11(7):e0160325. PubMed PMID: 27182980; PubMed Central PMCID: PMC4868347.


25. Xiao Y, Ma Z, Wang R, Yang L, Nan Y, Zhang YJ. Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage infection. Vet Microbiol. 2016 May 1;187:1-7. doi: 10.1016/j.vetmic.2016.03.004. Epub 2016 Mar 7. PubMed PMID: 27066702.


26. Guo R, Katz BB, Tomich JM, Gallagher T, Fang Y. Porcine Reproductive and Respiratory Syndrome Virus Utilizes Nanotubes for Intercellular Spread. J Virol.  2016 Apr 29;90(10):5163-75. doi: 10.1128/JVI.00036-16. Print 2016 May 15. PubMed  PMID: 26984724; PubMed Central PMCID: PMC4859731.


27. Wilkinson JM, Ladinig A, Bao H, Kommadath A, Stothard P, Lunney JK, Harding JC, Plastow GS. Differences in Whole Blood Gene Expression Associated with Infection Time-Course and Extent of Fetal Mortality in a Reproductive Model of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection. PLoS One. 2016 Apr 19;11(4):e0153615. doi: 10.1371/journal.pone.0153615. eCollection 2016. PubMed PMID: 27093427; PubMed Central PMCID: PMC4836665.\


28. Khatun A, Shabir N, Seo BJ, Kim BS, Yoon KJ, Kim WI. The Attenuation Phenotype of a Ribavirin-Resistant Porcine Reproductive and Respiratory Syndrome  Virus Is Maintained during Sequential Passages in Pigs. J Virol. 2016 Apr 14;90(9):4454-68. doi: 10.1128/JVI.02836-15. Print 2016 May. PubMed PMID: 26889041; PubMed Central PMCID: PMC4836337.


29. Hu Y, Cong X, Chen L, Qi J, Wu X, Zhou M, Yoo D, Li F, Sun W, Wu J, Zhao X, Chen Z, Yu J, Du Y, Wang J. Synergy of TLR3 and 7 ligands significantly enhances  function of DCs to present inactivated PRRSV antigen through TRIF/MyD88-NF-κB signaling pathway. Sci Rep. 2016 Apr 5;6:23977. doi: 10.1038/srep23977. PubMed PMID: 27046485; PubMed Central PMCID: PMC4820752.


30. Cao QM, Subramaniam S, Ni YY, Cao D, Meng XJ. The non-structural protein Nsp2TF of porcine reproductive and respiratory syndrome virus down-regulates the  expression of Swine Leukocyte Antigen class I. Virology. 2016 Apr;491:115-24. doi: 10.1016/j.virol.2016.01.021. Epub 2016 Feb 16. PubMed PMID: 26895249.


31. Zhang J. Coinfection with type 1 and type 2 PRRSV. Vet Rec. 2016 Mar 19;178(12):288-90. doi: 10.1136/vr.i1505. PubMed PMID: 26993451. 


32. Ouyang K, Hiremath J, Binjawadagi B, Shyu DL, Dhakal S, Arcos J, Schleappi R, Holman L, Roof M, Torrelles JB, Renukaradhya GJ. Comparative analysis of routes of immunization of a live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in a heterologous virus challenge study. Vet Res. 2016 Mar 17;47:45. doi: 10.1186/s13567-016-0331-3. PubMed PMID: 26988085; PubMed Central PMCID: PMC4797253.


33. Schroyen M, Eisley C, Koltes JE, Fritz-Waters E, Choi I, Plastow GS, Guan L,  Stothard P, Bao H, Kommadath A, Reecy JM, Lunney JK, Rowland RR, Dekkers JC, Tuggle CK. Bioinformatic analyses in early host response to Porcine Reproductive  and Respiratory Syndrome virus (PRRSV) reveals pathway differences between pigs with alternate genotypes for a major host response QTL. BMC Genomics. 2016 Mar 8;17:196. doi: 10.1186/s12864-016-2547-z. PubMed PMID: 26951612; PubMed Central PMCID: PMC4782518.


34. Kuhn JH, Lauck M, Bailey AL, Shchetinin AM, Vishnevskaya TV, Bào Y, Ng TF, LeBreton M, Schneider BS, Gillis A, Tamoufe U, Diffo Jle D, Takuo JM, Kondov NO,  Coffey LL, Wolfe ND, Delwart E, Clawson AN,Postnikova E, Bollinger L, Lackemeyer MG, Radoshitzky SR, Palacios G, Wada J, Shevtsova ZV, Jahrling PB, Lapin BA, Deriabin PG, Dunowska M, Alkhovsky SV, Rogers J, Friedrich TC, O'Connor DH, Goldberg TL. Reorganization and expansion of the nidoviral family Arteriviridae. Arch Virol. 2016 Mar;161(3):755-68. doi: 10.1007/s00705-015-2672-z. Epub 2015 Nov 25. PubMed PMID: 26608064; PubMed Central PMCID: PMC5573231.


35. Zhang Q, Huang C, Yang Q, Gao L, Liu HC, Tang J, Feng WH. MicroRNA-30c Modulates Type I IFN Responses To Facilitate Porcine Reproductive and Respiratory Syndrome Virus Infection by Targeting JAK1. J Immunol. 2016 Mar 1;196(5):2272-82. doi: 10.4049/jimmunol.1502006. Epub 2016 Jan 29. PubMed PMID: 26826240.


36. Valdes-Donoso P, Jarvis LS, Wright D, Alvarez J, Perez AM. Measuring Progress on the Control of Porcine Reproductive and Respiratory Syndrome (PRRS) at a Regional Level: The Minnesota N212 Regional Control Project (Rcp) as a Working Example. PLoS One. 2016 Feb 19;11(2):e0149498. doi: 10.1371/journal.pone.0149498. eCollection 2016. PubMed PMID: 26895148; PubMed Central PMCID: PMC4760934.


37. Alkhamis MA, Perez AM, Murtaugh MP, Wang X, Morrison RB. Applications of Bayesian Phylodynamic Methods in a Recent U.S. Porcine Reproductive and Respiratory Syndrome Virus Outbreak. Front Microbiol. 2016 Feb 2;7:67. doi: 10.3389/fmicb.2016.00067. eCollection 2016. PubMed PMID: 26870024; PubMed Central PMCID: PMC4735353.


38. Piñeyro PE, Kenney SP, Giménez-Lirola LG, Opriessnig T, Tian D, Heffron CL, Meng XJ. Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus. Virus Res. 2016 Feb 2;213:100-108. doi: 10.1016/j.virusres.2015.11.005. Epub 2015 Nov 7. PubMed PMID: 26555162.


39. Wang X, Zhang H, Abel AM, Nelson E. Protein kinase R (PKR) plays a pro-viral  role in porcine reproductive and respiratory syndrome virus (PRRSV) replication by modulating viral gene transcription. Arch Virol. 2016 Feb;161(2):327-33. doi:  10.1007/s00705-015-2671-0. Epub 2015 Nov 7. PubMed PMID: 26547579.


40. Alvarez J, Valdes-Donoso P, Tousignant S, Alkhamis M, Morrison R, Perez A. Novel analytic tools for the study of porcine reproductive and respiratory syndrome virus (PRRSv) in endemic settings: lessons learned in the U.S. Porcine Health Manag. 2016 Jan 21;2:3. doi: 10.1186/s40813-016-0019-0. eCollection 2016.  Review. PubMed PMID: 28405429; PubMed Central PMCID: PMC5382381.


41. Li Y, Shyu DL, Shang P, Bai J, Ouyang K, Dhakal S, Hiremath J, Binjawadagi B, Renukaradhya GJ, Fang Y. Mutations in a Highly Conserved Motif of nsp1β Protein Attenuate the Innate Immune Suppression Function of Porcine Reproductive and Respiratory Syndrome Virus. J Virol. 2016 Jan 20;90(7):3584-99. doi: 10.1128/JVI.03069-15. PubMed PMID: 26792733; PubMed Central PMCID: PMC4794661.


42. Alonso C, Raynor PC, Davies PR, Morrison RB, Torremorell M. Evaluation of an electrostatic particle ionization technology for decreasing airborne pathogens in pigs. Aerobiologia (Bologna). 2016;32(3):405-419. Epub 2015 Dec 8. PubMed PMID: 27616810; PubMed Central PMCID: PMC4996881.


43. Lunney JK, Fang Y, Ladinig A, Chen N, Li Y, Rowland B, Renukaradhya GJ. Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Pathogenesis and Interaction with the Immune System. Annu Rev Anim Biosci. 2016;4:129-54. doi: 10.1146/annurev-animal-022114-111025. Epub 2015 Nov 20. Review. PubMed PMID: 26646630.


44. Tian D, Meng XJ. Amino acid residues Ala283 and His421 in the RNA-dependent RNA polymerase of porcine reproductive and respiratory syndrome virus play important roles in viral ribavirin sensitivity and quasispecies diversity. J Gen  Virol. 2016 Jan;97(1):53-9. doi: 10.1099/jgv.0.000316. Epub 2015 Oct 19. PubMed PMID: 26487085.


45. Whitworth KM, Rowland RR, Ewen CL, Trible BR, Kerrigan MA, Cino-Ozuna AG, Samuel MS, Lightner JE, McLaren DG, Mileham AJ, Wells KD, Prather RS. Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus. Nat  Biotechnol. 2016 Jan;34(1):20-2. doi: 10.1038/nbt.3434. Epub 2015 Dec 7. PubMed PMID: 26641533.

 

Porcine circovirus:

1. Xiao CT, Harmon KM, Halbur PG, Opriessnig T. PCV2d-2 is the predominant type of PCV2 DNA in pig samples collected in the U.S. during 2014-2016. Vet Microbiol. 2016 Dec 25;197:72-77. doi: 10.1016/j.vetmic.2016.11.009. Epub 2016 Nov 11. PubMed PMID: 27938686.


2. Rogers AJ, Huang YW, Heffron CL, Opriessnig T, Patterson AR, Meng XJ. Prevalence of the Novel Torque Teno Sus Virus Species k2b from Pigs in the United States and Lack of Association with Post-Weaning Multisystemic Wasting Syndrome or Mulberry Heart Disease. Transbound Emerg Dis. 2016 Nov 23. doi: 10.1111/tbed.12586. [Epub ahead of print] PubMed PMID: 27878979.


3. Phan TG, Giannitti F, Rossow S, Marthaler D, Knutson TP, Li L, Deng X, Resende T, Vannucci F, Delwart E. Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation. Virol J. 2016 Nov 11;13(1):184. doi: 10.1186/s12985-016-0642-z. Erratum in: Virol J. 2017 Apr 28;14 (1):87. PubMed PMID: 27835942; PubMed Central PMCID: PMC5105309.


4. Palinski R, Piñeyro P, Shang P, Yuan F, Guo R, Fang Y, Byers E, Hause BM. A Novel Porcine Circovirus Distantly Related to Known Circoviruses Is Associated with Porcine Dermatitis and Nephropathy Syndrome and Reproductive Failure. J Virol. 2016 Dec 16;91(1). pii: e01879-16. Print 2017 Jan 1. PubMed PMID: 27795441; PubMed Central PMCID: PMC5165205.


5. Matzinger SR, Opriessnig T, Xiao CT, Catanzaro N, Beach NM, Slade DE, Nitzel GP, Meng XJ. A chimeric virus created by DNA shuffling of the capsid genes of different subtypes of porcine circovirus type 2 (PCV2) in the backbone of the non-pathogenic PCV1 induces protective immunity against the predominant PCV2b and the emerging PCV2d in pigs. Virology. 2016 Nov;498:82-93. doi: 10.1016/j.virol.2016.08.011. Epub 2016 Aug 24. PubMed PMID: 27564544.


6. Shi X, Liu X, Wang Q, Das A, Ma G, Xu L, Sun Q, Peddireddi L, Jia W, Liu Y,  Anderson G, Bai J, Shi J. A multiplex real-time PCR panel assay for simultaneous  detection and differentiation of 12 common swine viruses. J Virol Methods. 2016 Oct;236:258-265. doi: 10.1016/j.jviromet.2016.08.005. Epub 2016 Aug 6. PubMed PMID: 27506582.


7. Dvorak CM, Yang Y, Haley C, Sharma N, Murtaugh MP. National reduction in porcine circovirus type 2 prevalence following introduction of vaccination. Vet Microbiol. 2016 Jun 30;189:86-90. doi: 10.1016/j.vetmic.2016.05.002. Epub 2016 May 3. PubMed PMID: 27259831.


8. Niederwerder MC, Jaing CJ, Thissen JB, Cino-Ozuna AG, McLoughlin KS, Rowland RR. Microbiome associations in pigs with the best and worst clinical outcomes following co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). Vet Microbiol. 2016 May 30;188:1-11. doi: 10.1016/j.vetmic.2016.03.008. Epub 2016 Mar 11. PubMed PMID: 27139023.


9. Davies B, Wang X, Dvorak CM, Marthaler D, Murtaugh MP. Diagnostic phylogenetics reveals a new Porcine circovirus 2 cluster. Virus Res. 2016 Jun 2;217:32-7. doi: 10.1016/j.virusres.2016.02.010. Epub 2016 Mar 3. PubMed PMID: 26948261.


10. Piñeyro PE, Kenney SP, Giménez-Lirola LG, Opriessnig T, Tian D, Heffron CL, Meng XJ. Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus. Virus Res. 2016 Feb 2;213:100-108. doi: 10.1016/j.virusres.2015.11.005. Epub 2015 Nov 7. PubMed PMID: 26555162.

 

Swine enteric coronaviruses:

1. Poonsuk K, Zhang J, Chen Q, Gonzalez W, da Silva Carrion LC, Sun Y, Ji J, Wang C, Main R, Zimmerman J, Giménez-Lirola L. Quantifying the effect of lactogenic antibody on porcine epidemic diarrhea virus infection in neonatal piglets. Vet Microbiol. 2016 Dec 25;197:83-92. doi: 10.1016/j.vetmic.2016.11.002. Epub 2016 Nov 11. PubMed PMID: 27938689.


2. Crawford K, Lager KM, Kulshreshtha V, Miller LC, Faaberg KS. Status of vaccines for porcine epidemic diarrhea virus in the United States and Canada. Virus Res. 2016 Dec 2;226:108-116. doi: 10.1016/j.virusres.2016.08.005. Epub 2016 Aug 18. Review. PubMed PMID: 27545066. 


3. Lin CM, Saif LJ, Marthaler D, Wang Q. Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains. Virus Res. 2016  Dec 2;226:20-39. doi: 10.1016/j.virusres.2016.05.023. Epub 2016 Jun 8. Review. PubMed PMID: 27288724.


4. Song Q, Stone S, Drebes D, Greiner LL, Dvorak CMT, Murtaugh MP. Characterization of anti-porcine epidemic diarrhea virus neutralizing activity in mammary secretions. Virus Res. 2016 Dec 2;226:85-92. doi: 10.1016/j.virusres.2016.06.002. Epub 2016 Jun 7. PubMed PMID: 27287711.


5. Langel SN, Paim FC, Lager KM, Vlasova AN, Saif LJ. Lactogenic immunity and vaccines for porcine epidemic diarrhea virus (PEDV): Historical and current concepts. Virus Res. 2016 Dec 2;226:93-107. doi: 10.1016/j.virusres.2016.05.016.  Epub 2016 May 19. Review. PubMed PMID: 27212686.


6. Zhang Q, Yoo D. Immune evasion of porcine enteric coronaviruses and viral modulation of antiviral innate signaling. Virus Res. 2016 Dec 2;226:128-141. doi: 10.1016/j.virusres.2016.05.015. Epub 2016 May 19. Review. PubMed PMID: 27212682. 


7. Diel DG, Lawson S, Okda F, Singrey A, Clement T, Fernandes MHV, Christopher-Hennings J, Nelson EA. Porcine epidemic diarrhea virus: An overview of current virological and serological diagnostic methods. Virus Res. 2016 Dec 2;226:60-70. doi: 10.1016/j.virusres.2016.05.013. Epub 2016 May 14. Review. PubMed PMID: 27189041.


8. Gerber PF, Lelli D, Zhang J, Strandbygaard B, Moreno A, Lavazza A, Perulli S,  Bøtner A, Comtet L, Roche M, Pourquier P, Wang C, Opriessnig T. Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains. Prev Vet Med. 2016 Dec 1;135:87-94. doi: 10.1016/j.prevetmed.2016.11.005. Epub 2016 Nov 8. PubMed PMID: 27931933.


9. Gerber PF, Xiao CT, Lager K, Crawford K, Kulshreshtha V, Cao D, Meng XJ, Opriessnig T. Increased frequency of porcine epidemic diarrhea virus shedding and lesions in suckling pigs compared to nursery pigs and protective immunity in nursery pigs after homologous re-challenge. Vet Res. 2016 Nov 21;47(1):118. PubMed PMID: 27871312; PubMed Central PMCID: PMC5118895.


10. Liu C, Ma Y, Yang Y, Zheng Y, Shang J, Zhou Y, Jiang S, Du L, Li J, Li F. Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases. J Biol Chem. 2016 Nov 18;291(47):24779-24786. Epub 2016 Oct 11. PubMed PMID: 27729455; PubMed Central PMCID: PMC5114425.


11. Niederwerder MC, Nietfeld JC, Bai J, Peddireddi L, Breazeale B, Anderson J, Kerrigan MA, An B, Oberst RD, Crawford K, Lager KM, Madson DM, Rowland RR, Anderson GA, Hesse RA. Tissue localization, shedding, virus carriage, antibody response, and aerosol transmission of Porcine epidemic diarrhea virus following inoculation of 4-week-old feeder pigs. J Vet Diagn Invest. 2016 Nov;28(6):671-678. Epub 2016 Oct 3. PubMed PMID: 27698163.


12. Hain KS, Joshi LR, Okda F, Nelson J, Singrey A, Lawson S, Martins M, Pillatzki A, Kutish GF, Nelson EA, Flores EF, Diel DG. Immunogenicity of a recombinant parapoxvirus expressing the spike protein of Porcine epidemic diarrhea virus. J Gen Virol. 2016 Oct;97(10):2719-2731. doi: 10.1099/jgv.0.000586. Epub 2016 Aug 24. PubMed PMID: 27558814.


13. Song Y, Singh P, Nelson E, Ramamoorthy S. A Computationally Designed Serological Assay for Porcine Epidemic Diarrhea Virus. J Clin Microbiol. 2016 Aug;54(8):2039-46. doi: 10.1128/JCM.00460-16. Epub 2016 May 25. PubMed PMID: 27225413; PubMed Central PMCID: PMC4963506.


14. Liu X, Wang Q. Reverse transcription-PCR assays for the differentiation of various US porcine epidemic diarrhea virus strains. J Virol Methods. 2016 Aug;234:137-41. doi: 10.1016/j.jviromet.2016.04.018. Epub 2016 Apr 28. PubMed PMID: 27134071.


15. Zhang J, Tsai YL, Lee PY, Chen Q, Zhang Y, Chiang CJ, Shen YH, Li FC, Chang HF, Gauger PC, Harmon KM, Wang HT. Evaluation of two singleplex reverse transcription-Insulated isothermal PCR tests and a duplex real-time RT-PCR test for the detection of porcine epidemic diarrhea virus and porcine deltacoronavirus. J Virol Methods. 2016 Aug;234:34-42. doi: 10.1016/j.jviromet.2016.03.016. Epub 2016 Apr 6. PubMed PMID: 27060624.


16. Wang L, Hayes J, Byrum B, Zhang Y. US variant porcine epidemic diarrhea virus: histological lesions and genetic characterization. Virus Genes. 2016 Aug;52(4):578-81. doi: 10.1007/s11262-016-1334-x. Epub 2016 Apr 8. PubMed PMID: 27059242.


17. Gao X, Li D, Zhao J, Xu F, Ge X, Guo X, Han J, Yang H, Zhou L. Complete Genome Sequence of Porcine Epidemic Diarrhea Virus from an Outbreak in a Vaccinated Farm in Shandong, China. Genome Announc. 2016 Jul 7;4(4). pii: e00619-16. doi: 10.1128/genomeA.00619-16. PubMed PMID: 27389267; PubMed Central PMCID: PMC4939784.


18. Trudeau MP, Verma H, Sampedro F, Urriola PE, Shurson GC, McKelvey J, Pillai SD, Goyal SM. Comparison of Thermal and Non-Thermal Processing of Swine Feed and  the Use of Selected Feed Additives on Inactivation of Porcine Epidemic Diarrhea Virus (PEDV). PLoS One. 2016 Jun 24;11(6):e0158128. doi: 10.1371/journal.pone.0158128. eCollection 2016. PubMed PMID: 27341670; PubMed Central PMCID: PMC4920390.


19. Bjustrom-Kraft J, Woodard K, Giménez-Lirola L, Rotolo M, Wang C, Sun Y, Lasley P, Zhang J, Baum D, Gauger P, Main R, Zimmerman J. Porcine epidemic diarrhea virus (PEDV) detection and antibody response in commercial growing pigs. BMC Vet Res. 2016 Jun 10;12:99. doi: 10.1186/s12917-016-0725-5. PubMed PMID: 27287624; PubMed Central PMCID: PMC4902975.


20. Chen Q, Gauger PC, Stafne MR, Thomas JT, Madson DM, Huang H, Zheng Y, Li G, Zhang J. Pathogenesis comparison between the United States porcine epidemic diarrhoea virus prototype and S-INDEL-variant strains in conventional neonatal piglets. J Gen Virol. 2016 May;97(5):1107-21. doi: 10.1099/jgv.0.000419. Epub 2016 Feb 3. PubMed PMID: 26841768.


21. Jarvis MC, Lam HC, Rovira A, Marthaler DG. Complete Genome Sequence of Porcine Epidemic Diarrhea Virus Strain COL/Cundinamarca/2014 from Colombia. Genome Announc. 2016 Apr 21;4(2). pii: e00239-16. doi: 10.1128/genomeA.00239-16.  PubMed PMID: 27103712; PubMed Central PMCID: PMC4841127.


22. Poonsuk K, Giménez-Lirola LG, Zhang J, Arruda P, Chen Q, Correa da Silva Carrion L, Magtoto R, Pineyro P, Sarmento L, Wang C, Sun Y, Madson D, Johnson J,  Yoon KJ, Zimmerman J, Main R. Does Circulating Antibody Play a Role in the Protection of Piglets against Porcine Epidemic Diarrhea Virus? PLoS One. 2016 Apr 6;11(4):e0153041. doi: 10.1371/journal.pone.0153041. eCollection 2016. PubMed PMID: 27050556; PubMed Central PMCID: PMC4822964.


23. Chen Q, Thomas JT, Giménez-Lirola LG, Hardham JM, Gao Q, Gerber PF,  Opriessnig T, Zheng Y, Li G, Gauger PC, Madson DM, Magstadt DR, Zhang J.  Evaluation of serological cross-reactivity and cross-neutralization between the United States porcine epidemic diarrhea virus prototype and S-INDEL-variant strains. BMC Vet Res. 2016 Apr 5;12:70. doi: 10.1186/s12917-016-0697-5. PubMed PMID: 27044253; PubMed Central PMCID: PMC4820917.


24. Perez AM, Alba A, Goede D, McCluskey B, Morrison R. Monitoring the Spread of  Swine Enteric  Coronavirus Diseases in the United States in the Absence of a Regulatory Framework. Front Vet Sci. 2016 Mar 14;3:18. doi: 10.3389/fvets.2016.00018. eCollection 2016. PubMed PMID: 27014703; PubMed Central PMCID: PMC4789556.


25. Dee S, Neill C, Singrey A, Clement T, Cochrane R, Jones C, Patterson G, Spronk G, Christopher-Hennings J, Nelson E. Modeling the transboundary risk of feed ingredients contaminated with porcine epidemic diarrhea virus. BMC Vet Res.  2016 Mar 12;12:51. doi: 10.1186/s12917-016-0674-z. PubMed PMID: 26968372; PubMed  Central PMCID: PMC4788872.


26. Schweer WP, Pearce SC, Burrough ER, Schwartz K, Yoon KJ, Sparks JC, Gabler NK. The effect of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus challenge on growing pigs II: Intestinal integrity and function. J Anim Sci. 2016 Feb;94(2):523-32. doi: 10.2527/jas.2015-9836. PubMed PMID: 27065122. 


27. Schweer WP, Schwartz K, Burrough ER, Yoon KJ, Sparks JC, Gabler NK. The effect of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus challenge on growing pigs I: Growth performance and digestibility. J Anim Sci. 2016 Feb;94(2):514-22. doi: 10.2527/jas.2015-9834. PubMed PMID: 27065121.


28. Zhang Q, Shi K, Yoo D. Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1. Virology. 2016 Feb;489:252-68. doi: 10.1016/j.virol.2015.12.010. Epub 2016 Jan 14. PubMed PMID: 26773386.


29. Beall A, Yount B, Lin CM, Hou Y, Wang Q, Saif L, Baric R. Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A. MBio. 2016 Jan 5;7(1):e01451-15. doi: 10.1128/mBio.01451-15. PubMed PMID: 26733065; PubMed Central PMCID: PMC4724997.


30. Alonso C, Raynor PC, Davies PR, Morrison RB, Torremorell M. Evaluation of an  electrostatic  particle ionization technology for decreasing airborne pathogens in pigs. Aerobiologia (Bologna). 2016;32(3):405-419. Epub 2015 Dec 8. PubMed PMID: 27616810; PubMed Central PMCID: PMC4996881.


31. Miller LC, Crawford KK, Lager KM, Kellner SG, Brockmeier SL. Evaluation of two real-time polymerase chain reaction assays for Porcine epidemic diarrhea virus (PEDV) to assess PEDV transmission in growing pigs. J Vet Diagn Invest. 2016 Jan;28(1):20-9. doi: 10.1177/1040638715621949. Epub 2015 Dec 23. PubMed PMID: 26699519.


32. Goede D, Morrison RB. Production impact & time to stability in sow herds infected with porcine epidemic diarrhea virus (PEDV). Prev Vet Med. 2016 Jan 1;123:202-207. doi: 10.1016/j.prevetmed.2015.11.010. Epub 2015 Dec 28. PubMed PMID: 26748596.


33. Jarvis MC, Lam HC, Zhang Y, Wang L, Hesse RA, Hause BM, Vlasova A, Wang Q, Zhang J, Nelson MI, Murtaugh MP, Marthaler D. Genomic and evolutionary inferences between American and global strains of porcine epidemic diarrhea virus. Prev Vet  Med. 2016 Jan 1;123:175-184. doi: 10.1016/j.prevetmed.2015.10.020. Epub 2015 Nov  10. PubMed PMID: 26611651.


34. Sasaki Y, Alvarez J, Sekiguchi S, Sueyoshi M, Otake S, Perez A. Epidemiological factors associated to spread of porcine epidemic diarrhea in Japan. Prev Vet Med. 2016 Jan 1;123:161-167. doi: 10.1016/j.prevetmed.2015.11.002. Epub 2015 Nov 7. PubMed PMID: 26588869.


35. Alvarez J, Goede D, Morrison R, Perez A. Spatial and temporal epidemiology of porcine epidemic diarrhea (PED) in the Midwest and Southeast regions of the United States. Prev Vet Med. 2016 Jan 1;123:155-160. doi: 10.1016/j.prevetmed.2015.11.003. Epub 2015 Nov 7. PubMed PMID: 26586344.


36. Madson DM, Arruda PH, Magstadt DR, Burrough ER, Hoang H, Sun D, Bower LP, Bhandari M, Gauger PC, Stevenson GW, Wilberts BL, Wang C, Zhang J, Yoon KJ. Characterization of Porcine Epidemic Diarrhea Virus Isolate US/Iowa/18984/2013 Infection in 1-Day-Old Cesarean-Derived Colostrum-Deprived Piglets. Vet Pathol. 2016 Jan;53(1):44-52. doi: 10.1177/0300985815591080. Epub 2015 Jun 25. PubMed PMID: 26113613.


37. Schumacher LL, Woodworth JC, Jones CK, Chen Q, Zhang J, Gauger PC, Stark CR, Main RG, Hesse RA, Tokach MD, Dritz SS. Evaluation of the minimum infectious dose of porcine epidemic diarrhea virus in virus-inoculated feed. Am J Vet Res. 2016 Oct;77(10):1108-13. doi: 10.2460/ajvr.77.10.1108. PubMed PMID: 27668582.


38. McCluskey BJ, Morrison R. Another emerging disease: Swine Enteric Coronaviruses. Prev Vet Med. 2016 Jan 1;123:154. doi: 10.1016/j.prevetmed.2015.12.001. PubMed PMID: 26773474. 

 

Influenza viruses:

1. Lee J, Henningson J, Ma J, Duff M, Lang Y, Li Y, Li Y, Nagy A, Sunwoo S, Bawa B, Yang J, Bai D, Richt JA, Ma W. Effects of PB1-F2 on the pathogenicity of H1N1  swine influenza virus in mice and pigs. J Gen Virol. 2016 Dec 23. doi: 10.1099/jgv.0.000695. [Epub ahead of print] PubMed PMID: 28008819.


2. Anderson TK, Macken CA, Lewis NS, Scheuermann RH, Van Reeth K, Brown IH, Swenson SL, Simon G, Saito T, Berhane Y, Ciacci-Zanella J, Pereda A, Davis CT, Donis RO, Webby RJ, Vincent AL. A Phylogeny-Based Global Nomenclature System and  Automated Annotation Tool for H1 Hemagglutinin Genes from Swine Influenza A Viruses. mSphere. 2016 Dec 14;1(6). pii: e00275-16. eCollection 2016 Nov-Dec. PubMed PMID: 27981236; PubMed Central PMCID:  PMC5156671.


3. Abente EJ, Kitikoon P, Lager KM, Gauger PC, Anderson TK, Vincent A. A highly pathogenic avian influenza virus H5N1 with 2009 pandemic H1N1 internal genes demonstrates increased replication and transmission in pigs. J Gen Virol. 2016 Dec 9. doi: 10.1099/jgv.0.000678. [Epub ahead of print] PubMed PMID: 27959778.  


4. Artiaga BL, Yang G, Hutchinson TE, Loeb JC, Richt JA, Lednicky JA, Salek-Ardakani S, Driver JP. Rapid control of pandemic H1N1 influenza by targeting NKT-cells. Sci Rep. 2016 Nov 29;6:37999. doi: 10.1038/srep37999. PubMed PMID: 27897246; PubMed Central PMCID: PMC5126553.


5. Nelson MI, Stucker KM, Schobel SA, Trovão NS, Das SR, Dugan VG, Nelson SW, Sreevatsan S, Killian ML, Nolting JM, Wentworth DE, Bowman AS. Introduction, Evolution, and Dissemination of Influenza A Viruses in Exhibition Swine in the United States during 2009 to 2013. J Virol. 2016 Nov 14;90(23):10963-10971. Print 2016 Dec 1. PubMed PMID: 27681134; PubMed Central PMCID: PMC5110178.


6. Schicker RS, Rossow J, Eckel S, Fisher N, Bidol S, Tatham L, Matthews-Greer J, Sohner K, Bowman AS, Avrill J, Forshey T, Blanton L, Davis CT, Schiltz J, Skorupski S, Berman L, Jang Y, Bresee JS, Lindstrom S, Trock SC, Wentworth D, Fry AM, de Fijter S, Signs K, DiOrio M, Olsen SJ, Biggerstaff M. Outbreak of Influenza A(H3N2) Variant Virus Infections Among Persons Attending Agricultural Fairs Housing Infected Swine - Michigan and Ohio, July-August 2016. MMWR Morb Mortal Wkly Rep. 2016 Oct 28;65(42):1157-1160. doi: 10.15585/mmwr.mm6542a1. PubMed PMID: 27787493.


7. Panyasing Y, Goodell C, Kittawornrat A, Wang C, Levis I, Desfresne L, Rauh R, Gauger PC, Zhang J,  Lin X, Azeem S, Ghorbani-Nezami S, Yoon KJ, Zimmerman J. Influenza A Virus Surveillance Based on Pre-Weaning Piglet Oral Fluid Samples. Transbound Emerg Dis. 2016 Oct;63(5):e328-38. doi: 10.1111/tbed.12307. Epub 2014  Dec 9. PubMed PMID: 25488821.


8. Abente EJ, Anderson TK, Rajao DS, Swenson S, Gauger PC, Vincent AL. The avian-origin H3N2 canine influenza virus that recently emerged in the United States has limited replication in swine. Influenza Other Respir Viruses. 2016 Sep;10(5):429-32. doi: 10.1111/irv.12395. Epub 2016 May 18. PubMed PMID: 27110913; PubMed Central PMCID: PMC4947940.


9. Bliss N, Nelson SW, Nolting JM, Bowman AS. Prevalence of Influenza A Virus in Exhibition Swine during Arrival at Agricultural Fairs. Zoonoses Public Health. 2016 Sep;63(6):477-85. doi: 10.1111/zph.12252. Epub 2016 Jan 11. PubMed PMID: 26750204.


10. Abente EJ, Santos J, Lewis NS, Gauger PC, Stratton J, Skepner E, Anderson TK, Rajao DS, Perez DR, Vincent AL. The Molecular Determinants of Antibody Recognition and Antigenic Drift in the H3 Hemagglutinin of Swine Influenza A Virus. J Virol. 2016 Aug 26;90(18):8266-80. doi: 10.1128/JVI.01002-16. Print 2016 Sep 15. PubMed PMID: 27384658; PubMed Central PMCID: PMC5008105.


11. Hernandez LA, Miller CL, Vaughn EM. Particle and subunit-based hemagglutinin vaccines provide protective efficacy against H1N1 influenza in pigs. Vet Microbiol. 2016 Aug 15;191:35-43. doi: 10.1016/j.vetmic.2016.05.011. Epub 2016 Jun 2. PubMed PMID: 27374905.


12. White SK, Ma W, McDaniel CJ, Gray GC, Lednicky JA. Serologic evidence of exposure to influenza D virus among persons with occupational contact with cattle. J Clin Virol. 2016 Aug;81:31-3. doi: 10.1016/j.jcv.2016.05.017. Epub 2016 May 31. PubMed PMID: 27294672.


13. Paccha B, Jones RM, Gibbs S, Kane MJ, Torremorell M, Neira-Ramirez V, Rabinowitz PM. Modeling risk of occupational zoonotic influenza infection in swine workers. J Occup Environ Hyg. 2016 Aug;13(8):577-87. doi: 10.1080/15459624.2016.1159688. PubMed PMID: 26950677.


14. Sandbulte MR, Gauger PC, Kitikoon P, Chen H, Perez DR, Roth JA, Vincent AL. Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type. Vaccine. 2016 Jul 19;34(33):3773-9. doi: 10.1016/j.vaccine.2016.06.001. Epub 2016 Jun 17. PubMed PMID: 27325350. 


15. Gutiérrez AH, Loving C, Moise L, Terry FE, Brockmeier SL, Hughes HR, Martin WD, De Groot AS. In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model. PLoS One. 2016 Jul 13;11(7):e0159237. doi: 10.1371/journal.pone.0159237. eCollection 2016. PubMed PMID: 27411061; PubMed Central PMCID: PMC4943726.


16. Balzli C, Lager K, Vincent A, Gauger P, Brockmeier S, Miller L, Richt JA, Ma  W, Suarez D, Swayne  DE. Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses. Influenza Other Respir Viruses. 2016 Jul;10(4):346-52. doi: 10.1111/irv.12386. Epub 2016 Apr 5. PubMed PMID: 26946338; PubMed Central PMCID:  PMC4910171. 


17. Rajão DS, Chen H, Perez DR, Sandbulte MR, Gauger PC, Loving CL, Shanks GD, Vincent A. Vaccine-associated enhanced respiratory disease is influenced by haemagglutinin and neuraminidase in whole inactivated influenza virus vaccines. J Gen Virol. 2016 Jul;97(7):1489-99. doi: 10.1099/jgv.0.000468. Epub 2016 Mar 31. PubMed PMID: 27031847.


18. Poulson RL, Tompkins SM, Berghaus RD, Brown JD, Stallknecht DE. Environmental Stability of Swine and Human Pandemic Influenza Viruses in Water under Variable Conditions of Temperature, Salinity, and pH. Appl Environ Microbiol. 2016 Jun 13;82(13):3721-6. doi: 10.1128/AEM.00133-16. Print 2016 Jul 1. PubMed PMID: 27084011; PubMed Central PMCID: PMC4907172.


19. Souza CK, Rajão DS, Loving CL, Gauger PC, Pérez DR, Vincent AL. Age at Vaccination and Timing of Infection Do Not Alter Vaccine-Associated Enhanced Respiratory Disease in Influenza A Virus-Infected Pigs. Clin Vaccine Immunol. 2016 Jun 6;23(6):470-82. doi: 10.1128/CVI.00563-15. Print 2016 Jun. PubMed PMID:  27030585; PubMed Central PMCID: PMC4895012. 


20. Kong W, Liu Q, Sun Y, Wang Y, Gao H, Liu L, Qin Z, He Q, Sun H, Pu J, Wang D, Guo X, Yang H, Chang KC, Shu Y, Liu J. Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs. Sci Rep. 2016 Jun 2;6:27067. doi: 10.1038/srep27067. PubMed PMID: 27252023; PubMed Central PMCID: PMC4890009.


21. Paccha B, Neira-Ramirez V, Gibbs S, Torremorell M, Rabinowitz PM. Swine Worker Precautions During Suspected Outbreaks of Influenza in Swine. J Environ Health. 2016 May;78(9):22-6; quiz 45. PubMed PMID: 27263180.


22. Hiremath J, Kang KI, Xia M, Elaish M, Binjawadagi B, Ouyang K, Dhakal S, Arcos J, Torrelles JB, Jiang X, Lee CW, Renukaradhya GJ. Entrapment of H1N1 Influenza Virus Derived Conserved Peptides in PLGA Nanoparticles Enhances T Cell  Response and Vaccine Efficacy in Pigs. PLoS One. 2016 Apr 19;11(4):e0151922. doi: 10.1371/journal.pone.0151922. eCollection 2016. PubMed PMID: 27093541; PubMed Central PMCID: PMC4836704.


23. Lewis NS, Russell CA, Langat P, Anderson TK, Berger K, Bielejec F, Burke DF,  Dudas G, Fonville JM, Fouchier RA, Kellam P, Koel BF, Lemey P, Nguyen T, Nuansrichy B, Peiris JM, Saito T, Simon G, Skepner E, Takemae N; ESNIP3 consortium, Webby RJ, Van Reeth K, Brookes SM, Larsen L, Watson SJ, Brown IH, Vincent AL. The global antigenic diversity of swine influenza A viruses. Elife. 2016 Apr 15;5:e12217. doi: 10.7554/eLife.12217. PubMed PMID: 27113719; PubMed Central PMCID: PMC4846380.


24. Dwivedi V, Manickam C, Dhakal S, Binjawadagi B, Ouyang K, Hiremath J, Khatri M, Hague JG, Lee CW, Renukaradhya GJ. Adjuvant effects of invariant NKT cell ligand potentiates the innate and adaptive immunity to an inactivated H1N1 swine  influenza virus vaccine in pigs. Vet Microbiol. 2016 Apr 15;186:157-63. doi: 10.1016/j.vetmic.2016.02.028. Epub 2016 Mar 2. PubMed PMID: 27016770.


25. Rajao DS, Sandbulte MR, Gauger PC, Kitikoon P, Platt R, Roth JA, Perez DR, Loving CL, Vincent AL. Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory  disease in weaned piglets. Virology. 2016 Apr;491:79-88. doi: 10.1016/j.virol.2016.01.015. Epub 2016 Feb 11. PubMed PMID: 26874588; PubMed Central PMCID: PMC4825855.


26. Krishna VD, Wu K, Perez AM, Wang JP. Giant Magnetoresistance-based Biosensor  for Detection of Influenza A Virus. Front Microbiol. 2016 Mar 29;7:400. doi: 10.3389/fmicb.2016.00400. eCollection 2016. PubMed PMID: 27065967; PubMed Central PMCID: PMC4809872.


27. Artiaga BL, Yang G, Hackmann TJ, Liu Q, Richt JA, Salek-Ardakani S, Castleman WL, Lednicky JA, Driver JP. α-Galactosylceramide protects swine against influenza infection when administered as a vaccine adjuvant. Sci Rep. 2016 Mar 23;6:23593.  doi: 10.1038/srep23593. PubMed PMID: 27004737; PubMed Central PMCID: PMC4804283.


28. Goodell CK, Prickett J, Kittawornrat A, Johnson J, Zhang J, Wang C, Zimmerman JJ. Evaluation of Screening Assays for the Detection of Influenza A Virus Serum Antibodies in Swine. Transbound Emerg Dis. 2016 Feb;63(1):24-35. doi: 10.1111/tbed.12214. Epub 2014 Feb 27. PubMed PMID: 24571447.


29. Bowman AS, Nolting JM, Workman JD, Cooper M, Fisher AE, Marsh B, Forshey T. The Inability to Screen Exhibition Swine for Influenza A Virus Using Body Temperature. Zoonoses Public Health. 2016 Feb;63(1):34-9. doi: 10.1111/zph.12201. Epub 2015 Apr 17. PubMed PMID: 25884907; PubMed Central PMCID: PMC4609228. 


30. Nelson MI, Wentworth DE, Das SR, Sreevatsan S, Killian ML, Nolting JM, Slemons RD, Bowman  AS. Evolutionary Dynamics of Influenza A Viruses in US  Exhibition Swine. J Infect Dis. 2016 Jan 15;213(2):173-82. doi: 10.1093/infdis/jiv399. Epub 2015 Aug 4. PubMed PMID: 26243317; PubMed Central PMCID: PMC4690152.  


31. Neira V, Rabinowitz P, Rendahl A, Paccha B, Gibbs SG, Torremorell M. Characterization of Viral Load, Viability and Persistence of Influenza A Virus in Air and on Surfaces of Swine Production Facilities. PLoS One. 2016 Jan 12;11(1):e0146616. doi: 10.1371/journal.pone.0146616. eCollection 2016. PubMed PMID: 26757362; PubMed Central PMCID: PMC4710569.  


32. Alonso C, Raynor PC, Davies PR, Morrison RB, Torremorell M. Evaluation of an  electrostatic particle ionization technology for decreasing airborne pathogens in pigs. Aerobiologia (Bologna). 2016;32(3):405-419. Epub 2015 Dec 8. PubMed PMID: 27616810; PubMed Central PMCID: PMC4996881.


33. Goodell CK, Zhang J, Strait E, Harmon K, Patnayak D, Otterson T, Culhane M, Christopher-Hennings J, Clement T, Leslie-Steen P, Hesse R, Anderson J, Skarbek K, Vincent A, Kitikoon P, Swenson S, Jenkins-Moore M, McGill J, Rauh R, Nelson W, O'Connell C, Shah R, Wang C, Main R, Zimmerman JJ. Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time reverse-transcription polymerase chain reaction and virus isolation. Can J Vet Res. 2016 Jan;80(1):12-20. PubMed PMID: 26733728; PubMed Central PMCID: PMC4686030.

 

Senecavirus:

1. Joshi LR, Fernandes MH, Clement T, Lawson S, Pillatzki A, Resende TP, Vannucci FA, Kutish GF, Nelson EA, Diel DG. Pathogenesis of Senecavirus A infection in finishing pigs. J Gen Virol. 2016 Dec;97(12):3267-3279. doi: 10.1099/jgv.0.000631. Epub 2016 Oct 14. PubMed PMID: 27902357. 


2. Chen Z, Yuan F, Li Y, Shang P, Schroeder R, Lechtenberg K, Henningson J, Hause B, Bai J, Rowland RRR, Clavijo A, Fang Y. Construction and characterization of a  full-length cDNA infectious clone of emerging porcine Senecavirus A. Virology. 2016 Oct;497:111-124. doi: 10.1016/j.virol.2016.07.003. Epub 2016 Jul 25. PubMed  PMID: 27459668.


3. Gimenez-Lirola LG, Rademacher C, Linhares D, Harmon K, Rotolo M, Sun Y, Baum DH, Zimmerman J, Piñeyro P. Serological and Molecular Detection of Senecavirus A  Associated with an Outbreak of Swine Idiopathic Vesicular Disease and Neonatal Mortality. J Clin Microbiol. 2016 Aug;54(8):2082-9. doi: 10.1128/JCM.00710-16. Epub 2016 May 25. PubMed PMID: 27225408; PubMed Central PMCID: PMC4963487. 


4. Montiel N, Buckley A, Guo B, Kulshreshtha V, VanGeelen A, Hoang H, Rademacher  C, Yoon KJ, Lager K. Vesicular Disease in 9-Week-Old Pigs Experimentally Infected with Senecavirus A. Emerg Infect Dis. 2016 Jul;22(7):1246-8. doi: 10.3201/eid2207.151863. PubMed PMID: 27315363; PubMed Central PMCID: PMC4918149.


5. Guo B, Piñeyro PE, Rademacher CJ, Zheng Y, Li G, Yuan J, Hoang H, Gauger PC, Madson DM, Schwartz KJ, Canning PE, Arruda BL, Cooper VL, Baum DH, Linhares DC, Main RG, Yoon KJ. Novel Senecavirus A in Swine with Vesicular Disease, United States, July 2015. Emerg Infect Dis. 2016 Jul;22(7):1325-7. doi: 10.3201/eid2207.151758. PubMed PMID: 27314645; PubMed Central PMCID: PMC4918180.


6. Canning P, Canon A, Bates JL, Gerardy K, Linhares DC, Piñeyro PE, Schwartz KJ, Yoon KJ, Rademacher CJ, Holtkamp D, Karriker L. Neonatal Mortality, Vesicular Lesions and Lameness Associated with Senecavirus A in a U.S. Sow Farm. Transbound Emerg Dis. 2016 Aug;63(4):373-8. doi: 10.1111/tbed.12516. Epub 2016 May 23. PubMed PMID: 27213868.


7. Hause BM, Myers O, Duff J, Hesse RA. Senecavirus A in Pigs, United States, 2015. Emerg Infect Dis. 2016 Jul;22(7):1323-5. doi: 10.3201/eid2207.151591. PubMed PMID: 27314580; PubMed Central PMCID: PMC4918151.


8. Wang L, Prarat M, Hayes J, Zhang Y. Detection and Genomic Characterization of  Senecavirus A, Ohio, USA, 2015. Emerg Infect Dis. 2016 Jul;22(7):1321-3. doi: 10.3201/eid2207.151897. PubMed PMID: 27314491; PubMed Central PMCID: PMC4918170. 


9. Joshi LR, Mohr KA, Clement T, Hain KS, Myers B, Yaros J, Nelson EA, Christopher-Hennings J, Gava D, Schaefer R, Caron L, Dee S, Diel DG. Detection of the Emerging Picornavirus Senecavirus A in Pigs, Mice, and Houseflies. J Clin Microbiol. 2016 Jun;54(6):1536-45. doi: 10.1128/JCM.03390-15. Epub 2016 Mar 30. PubMed PMID: 27030489; PubMed Central PMCID: PMC4879313.

 

Others:

12/03/2017

03/20/1970

Publications/funding sources for 2018 and over the past five years are detailed in the NC-229 renewal project proposal.